Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Gui J. Yu"'
Autor:
Choong L. Yoo, Baoxue Yang, Brandi M. Hudson, Mark J. Kurth, Gui J. Yu, Huy Nguyen, Dean J. Tantillo, Alan S. Verkman, Michael W. Lodewyk, Puay Wah Phuan, Deanna Montgomery, Alex L. Bagdasarian, Keith C. Coffman
Publikováno v:
Journal of Medicinal Chemistry
Conformationally constrained bithiazoles were previously found to have improved efficacy over nonconstrained bithiazoles for correction of defective cellular processing of the ΔF508 mutant cystic fibrosis transmembrane conductance regulator (CFTR) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41d6e8404d5899fdc52c2ea8d8d05ff
https://doi.org/10.1021/jm5007885
https://doi.org/10.1021/jm5007885
Autor:
James C. Fettinger, Thomas C. Sparks, Gui J. Yu, Lori I. Robins, Mark J. Kurth, Beth A. Lorsbach, Satori Iwamoto
A collection of ninety-one 3-(arylthiomethyl)isoxazole-4,5-dicarboxamides were prepared starting from dimethyl 3-(chloromethyl)isoxazole-4,5-dicarboxylate. The thioether moieties in these compounds were subsequently oxidized to give the corresponding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6236adf7c717bf1e257d743039e707a9
https://europepmc.org/articles/PMC2847632/
https://europepmc.org/articles/PMC2847632/
