Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Gui‐Juan Cheng"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract C2′-halogenation has been recognized as an essential modification to enhance the drug-like properties of nucleotide analogs. The direct C2ʹ-halogenation of the nucleotide 2′-deoxyadenosine-5′-monophosphate (dAMP) has recently been ach
Externí odkaz:
https://doaj.org/article/defdba2edc92446ba67f1332e1ccf5d6
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2086-2099 (2023)
In epigenetic mechanisms, DNA methyltransferase 3 alpha (DNMT3A) acts as an initiator for DNA methylation and prevents the downstream genes from expressing. Perturbations of DNMT3A functions may cause uncontrolled gene expression, resulting in pathog
Externí odkaz:
https://doaj.org/article/9ee43aba44564e899fdeff204da3bea4
Publikováno v:
JACS Au, Vol 2, Iss 3, Pp 745-761 (2022)
Externí odkaz:
https://doaj.org/article/3e758f4fe7864cae8ad879531002aaf3
Mechanistic insights into reductive deamination with hydrosilanes catalyzed by B(C6F5)3: A DFT study
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Selective defunctionalization of synthetic intermediates is a valuable approach in organic synthesis. Here, we present a theoretical study on the recently developed B(C6F5)3/hydrosilane-mediated reductive deamination reaction of primary amines. Our c
Externí odkaz:
https://doaj.org/article/81354c6410374ef69e7c7a425bf1f2c3
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Selective oxidation is one of the most important and challenging transformations in both academic research and chemical industry. Recently, a highly selective and efficient way to synthesize biologically active γ-hydroxy-α,β-unsaturated m
Externí odkaz:
https://doaj.org/article/773a688c7a5140b8a8ed307fc898bedd
Publikováno v:
ACS Catalysis. 13:1863-1874
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a86bd83fa384ef26abddedac00c70cfd
https://doi.org/10.1021/acscatal.2c06046
https://doi.org/10.1021/acscatal.2c06046
Publikováno v:
ACS Catalysis. 12:14582-14591
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa00405ce20c3748fb9bb5e119806fb4
https://doi.org/10.1021/acscatal.2c04211
https://doi.org/10.1021/acscatal.2c04211
Publikováno v:
Angewandte Chemie International Edition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a06aa57080137a24cf4389ff357b1bb
https://doi.org/10.1002/anie.202304543
https://doi.org/10.1002/anie.202304543
Autor:
Hsi-Yuan Huang, Yang-Chi-Dung Lin, Shidong Cui, Yixian Huang, Yun Tang, Jiatong Xu, Jiayang Bao, Yulin Li, Jia Wen, Huali Zuo, Weijuan Wang, Jing Li, Jie Ni, Yini Ruan, Liping Li, Yidan Chen, Yueyang Xie, Zihao Zhu, Xiaoxuan Cai, Xinyi Chen, Lantian Yao, Yigang Chen, Yijun Luo, Shupeng LuXu, Mengqi Luo, Chih-Min Chiu, Kun Ma, Lizhe Zhu, Gui-Juan Cheng, Chen Bai, Ying-Chih Chiang, Liping Wang, Fengxiang Wei, Tzong-Yi Lee, Hsien-Da Huang
Publikováno v:
Nucleic Acids Research
MicroRNAs (miRNAs) are noncoding RNAs with 18–26 nucleotides; they pair with target mRNAs to regulate gene expression and produce significant changes in various physiological and pathological processes. In recent years, the interaction between miRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3ac440514ee7725cf9049cdfa9a120
https://doi.org/10.1093/nar/gkab1079
https://doi.org/10.1093/nar/gkab1079
Publikováno v:
ACS Catalysis. 11:7578-7583
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eaab6cfd441c62017cc7143c37ce5f0
https://doi.org/10.1021/acscatal.1c01971
https://doi.org/10.1021/acscatal.1c01971