Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Gui‐Feng Zhou"'
Autor:
Li Song, Qiu‐Ling Pan, Gui‐Feng Zhou, Sheng‐Wei Liu, Bing‐Lin Zhu, Pei‐Jia Lin, Xiao‐Tong Hu, Jing‐Si Zha, Yan Long, Biao Luo, Jian Chen, Ying Tang, Jing Tang, Xiao‐Jiao Xiang, Xiao‐Yong Xie, Xiao‐Juan Deng, Guo‐Jun Chen
Publikováno v:
Advanced Science, Vol 11, Iss 11, Pp n/a-n/a (2024)
Abstract It is long been suggested that one‐carbon metabolism (OCM) is associated with Alzheimer's disease (AD), whereas the potential mechanisms remain poorly understood. Taking advantage of chemical biology, that mitochondrial serine hydroxymethy
Externí odkaz:
https://doaj.org/article/05748bcfdf2b4138810dae2b4810b884
Autor:
Jian Chen, Biao Luo, Bi-Rou Zhong, Kun-Yi Li, Qi-Xin Wen, Li Song, Xiao-Jiao Xiang, Gui-Feng Zhou, Li-Tian Hu, Xiao-Juan Deng, Yuan-Lin Ma, Guo-Jun Chen
Publikováno v:
Genes and Diseases, Vol 8, Iss 6, Pp 867-881 (2021)
Sulfuretin is a flavonoid that protects cell from damage induced by reactive oxygen species and inflammation. In this study, we investigated the role of sulfuretin in the processing of amyloid precursor protein (APP), in association with the two cata
Externí odkaz:
https://doaj.org/article/67b39b39ae2a43ac81a57e12a858650c
Autor:
Biao Luo, Jian Chen, Gui‐Feng Zhou, Xiao‐Yong Xie, Jing Tang, Qi‐Xin Wen, Li Song, Shi‐Qi Xie, Yan Long, Guo‐Jun Chen, Xiao‐Tong Hu
Publikováno v:
CNS Neuroscience & Therapeutics. 29:1300-1311
Autor:
Gui-Feng Zhou, Jing Tang, Yuan-Lin Ma, Xian Fu, Jun-Yan Liu, Ren-Zhi Yang, Hong-Sheng Zhang, Xiang-Hai Cai, Jing-Wen Wang, Xiao-Yong Xie, Li Song, Biao Luo, Jian Chen, Long Chen, Xiao-Juan Deng, Guo-Jun Chen
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Exploring the potential lead compounds for Alzheimer’s disease (AD) remains one of the challenging tasks. Here, we report that the plant extract conophylline (CNP) impeded amyloidogenesis by preferentially inhibiting BACE1 translation via the 5′
Autor:
Li-Tian Hu, Xiao-Yong Xie, Gui-Feng Zhou, Qi-Xin Wen, Li Song, Biao Luo, Xiao-Juan Deng, Qiu-Ling Pan, Guo-Jun Chen
Publikováno v:
Journal of Alzheimer's disease : JAD. 91(1)
Background: Accumulation of hyperphosphorylated Tau (pTau) contributes to the formation of neurofibrillary tangles in Alzheimer’s disease (AD), and targeting Tau/pTau metabolism has emerged as a therapeutic approach. We have previously reported tha
Autor:
Qi‐Xin Wen, Biao Luo, Xiao‐Yong Xie, Gui‐Feng Zhou, Jian Chen, Li Song, Yue Liu, Shi‐Qi Xie, Long Chen, Kun‐Yi Li, Xiao‐Jiao Xiang, Guo‐Jun Chen
Publikováno v:
Traffic (Copenhagen, Denmark)REFERENCES.
AP2S1 is the sigma 2 subunit of adaptor protein 2 (AP2) that is essential for endocytosis. In this study, we investigated the potential role of AP2S1 in intracellular processing of amyloid precursor protein (APP), which contributes to the pathogenesi
Autor:
Long Chen, Lu Wang, Gui-Feng Zhou, Yue Liu, Xue Chen, Xiao-Yong Xie, Qi-Xin Wen, Chen-Lu Li, Jie Yang, Guo-Jun Chen
Publikováno v:
Neuroscience Letters. 808:137265
Autor:
Bi-Rou Zhong, Guojun Chen, Li Song, Biao Luo, Yuanlin Ma, Li-Tian Hu, Gui-Feng Zhou, Qi-Xin Wen, Xiao-Juan Deng, Kun-Yi Li, Xiao-Jiao Xiang, Jian Chen
Publikováno v:
Journal of Neurochemistry. 157:1351-1365
Thioredoxin-2 (TXN2) is a mitochondrial protein and represents one of the intrinsic antioxidant enzymes. It has long been recognized that mitochondrial dysfunction and oxidative stress contribute to the pathogenesis of Alzheimer's disease (AD). We hy
Publikováno v:
Journal of Iron and Steel Research International. 26:1199-1208
The hydrogen-induced delayed cracking (HIDC) behaviors of two types of 1500 MPa grade hot stamping steels (HSSs) have been investigated by the method of slow strain rate tensile test and hydrogen permeation, where one is manufactured by compact strip