Zobrazeno 1 - 10
of 600
pro vyhledávání: '"Gui, Gao"'
Autor:
Jianqing Lin, Xinfu Yan, Zara Chung, Chong Wai Liew, Abbas El Sahili, Evgeniya V. Pechnikova, Peter R. Preiser, Zbynek Bozdech, Yong-Gui Gao, Julien Lescar
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract In the absence of an efficacious vaccine, chemotherapy remains crucial to prevent and treat malaria. Given its key role in haemoglobin degradation, falcilysin constitutes an attractive target. Here, we reveal the mechanism of enzymatic inhib
Externí odkaz:
https://doaj.org/article/884a7bfcc9134996806c5745785f14a6
Autor:
Guang-Lei Ma, Wan-Qiu Liu, Huawei Huang, Xin-Fu Yan, Wei Shen, Surawit Visitsatthawong, Kridsadakorn Prakinee, Hoa Tran, Xiaohui Fan, Yong-Gui Gao, Pimchai Chaiyen, Jian Li, Zhao-Xun Liang
Publikováno v:
JACS Au, Vol 4, Iss 8, Pp 2925-2935 (2024)
Externí odkaz:
https://doaj.org/article/719a4b5be29445a1bfb02fb5c3b81cc7
Autor:
Justis P. Ehlers, MD, Allen Hu, MD, David Boyer, MD, Scott W. Cousins, MD, Nadia K. Waheed, MD, Philip J. Rosenfeld, MD, PhD, David Brown, MD, Peter K. Kaiser, MD, Anthony Abbruscato, PharmD, Gui Gao, PhD, Jeffrey Heier, MD, Prema Abraham, Christopher Devine, Anita Schadlu, George Novalis, Derek Y. Kunimoto, John Parchue, Suk Jin Moon, Zachary Segal, Dennis Marcus, Paul Hahn, Eric Suan, Michael Lee, Victor Gonzalez, Michael A. Samuel, Sunil Patel, Patrick Williams, Brian B. Berger, Henry Kwong, Dante Pieramici, Eric W. Schneider, Yevgeniy Shildkrot, Mathew T. Witmer, Nathan Steinle, Carmelina Gordon, Daniel Learned, Patrick Higgins, Guruprasad Pattar, Vijay Khetpal, Robin Ross, Mark R. Barakat, Sun Young Lee Sjatkowski, David Lally, Troy Becker
Publikováno v:
Ophthalmology Science, Vol 5, Iss 1, Pp 100628- (2025)
Objective: This study evaluated the safety and efficacy of elamipretide in dry age-related macular degeneration (AMD) with noncentral geographic atrophy (GA). Design: ReCLAIM-2 was a prospective, phase II, randomized, placebo-controlled, double-maske
Externí odkaz:
https://doaj.org/article/7164fb5412894bafbf1cb11d512f531f
Autor:
Pazhanichamy Kalailingam, Khalilatul‐Hanisah Mohd‐Kahliab, SoFong Cam Ngan, Ranjith Iyappan, Evelin Melekh, Tian Lu, Gan Wei Zien, Bhargy Sharma, Tiannan Guo, Adam J MacNeil, Rebecca EK MacPherson, Evangelia Litsa Tsiani, Deborah D O'Leary, Kah Leong Lim, I Hsin Su, Yong‐Gui Gao, A Mark Richards, Raj N Kalaria, Christopher P Chen, Neil E McCarthy, Siu Kwan Sze
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-16 (2023)
Abstract Aging results from the accumulation of molecular damage that impairs normal biochemical processes. We previously reported that age‐linked damage to amino acid sequence NGR (Asn‐Gly‐Arg) results in “gain‐of‐function” conformatio
Externí odkaz:
https://doaj.org/article/0e78e068254840989c041da6a4477442
Publikováno v:
气体物理, Vol 8, Iss 5, Pp 61-69 (2023)
The effect of the turbine exhaust pipe on flow structure and aerodynamic heating of the rocket base was investigated by numerical simulation of the four-nozzle liquid rocket with and without turbine exhaust pipe. Based on the three-dimensional multi-
Externí odkaz:
https://doaj.org/article/30ea7396487543b39224d9048c593380
Autor:
Xi Shen, Zixiang Yang, Zihan Li, Dan Xiong, Jinxing Liao, Weimei He, Danyu Shen, Xiaolong Shao, Ben Niu, Yongxing He, Yong‐Gui Gao, Guoliang Qian
Publikováno v:
mLife, Vol 2, Iss 3, Pp 295-307 (2023)
Abstract To remain competitive, proteobacteria use various contact‐dependent weapon systems to defend against microbial competitors. The bacterial‐killing type IV secretion system (T4SS) is one such powerful weapon. It commonly controls the killi
Externí odkaz:
https://doaj.org/article/99cda5f750344fdbbd055c8d4d2ef9a6
Autor:
Zhibin Liang, Qiqi Lin, Qingwei Wang, Luhao Huang, Huidi Liu, Zurong Shi, Zining Cui, Xiaofan Zhou, Yong-Gui Gao, Jianuan Zhou, Lian-Hui Zhang, Yizhen Deng
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Envelope stress responses (ESRs) are critical for adaptive resistance of Gram-negative bacteria to envelope-targeting antimicrobial agents. However, ESRs are poorly defined in a large number of well-known plant and human pathogens
Externí odkaz:
https://doaj.org/article/d5b9f400597b407484a6d6670d0f68ff
Publikováno v:
Remote Sensing, Vol 16, Iss 9, p 1533 (2024)
Synthetic Aperture Radar (SAR) has the advantage of continuous observation throughout the day and in all weather conditions, and is used in a wide range of military and civil applications. Among these, the detection of ships at sea is an important re
Externí odkaz:
https://doaj.org/article/12f8775ead7c41e8bf4a7fc6cf488de6
Publikováno v:
Brain Research Bulletin, Vol 187, Iss , Pp 169-180 (2022)
Background: Postoperative cognitive decline (POCD) is a common complication after surgery and anesthesia among the elderly. Yet the potential mechanism of POCD remains ambiguous, with limited therapeutic measures currently available. Ketamine has bee
Externí odkaz:
https://doaj.org/article/e038b28c6c9f443e9dd59685503f5b63
Publikováno v:
Zhongguo dizhi zaihai yu fangzhi xuebao, Vol 33, Iss 3, Pp 94-105 (2022)
Landslide is a kind of natural geological disaster with strong destructive power, long-term effective time-series deformation monitoring of landslide prone areas is an important way to prevent and mitigate disasters, and the application of time-serie
Externí odkaz:
https://doaj.org/article/84d9f842bad5451ab64fa6eccf7c43df