Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Guey Yueh Shi"'
Autor:
Yi-Kai Hong, Yu-Chen Lin, Tsung-Lin Cheng, Chao-Han Lai, Yi-Han Chang, Yu-Lun Huang, Chia-Yi Hung, Chen-Han Wu, Kuo-Shu Hung, Ya-Chu Ku, Yen-Ting Ho, Ming-Jer Tang, Shu-Wha Lin, Guey-Yueh Shi, John A. McGrath, Hua-Lin Wu, Chao-Kai Hsu
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-25 (2024)
Abstract Background Pathologic scars, including keloids and hypertrophic scars, represent a common form of exaggerated cutaneous scarring that is difficult to prevent or treat effectively. Additionally, the pathobiology of pathologic scars remains po
Externí odkaz:
https://doaj.org/article/0668ee67d3c444a6ab6d5c3bd3c22df6
Autor:
Gang-Hui Lee, Chia-Lin Chang, Wen-Tai Chiu, Tsun-Hsien Hsiao, Po-Yuan Chen, Kuan-Chieh Wang, Cheng-Hsiang Kuo, Bing-Hung Chen, Guey-Yueh Shi, Hua-Lin Wu, Tzu-Fun Fu
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-20 (2019)
Abstract Background Thrombomodulin (TM), an integral membrane protein, has long been known for its anticoagulant activity. Recent studies showed that TM displays multifaceted activities, including the involvement in cell adhesion and collective cell
Externí odkaz:
https://doaj.org/article/1c02c41bb5e4435eb241c51bf69da9a2
Autor:
Vincent Chunpeng Pai, I-Chung Lo, Yan wun Huang, I-Ching Tsai, Hui-Pin Cheng, Guey-Yueh Shi, Hua-Lin Wu, Meei Jyh Jiang
Publikováno v:
Journal of Biomedical Science, Vol 25, Iss 1, Pp 1-12 (2018)
Abstract Background Thrombomodulin (TM), a transmembrane glycoprotein highly expressed in endothelial cells (ECs), is a potent anticoagulant maintaining circulation homeostasis. Under inflammatory states, TM expression is drastically reduced in ECs w
Externí odkaz:
https://doaj.org/article/b2abd6391b7d4a5d8647ad3e328d8b7e
Autor:
Po-Sheng Chen, Kuan-Chieh Wang, Ting-Hsing Chao, Hsing-Chun Chung, Shi-Ya Tseng, Chawn-Yau Luo, Guey-Yueh Shi, Hua-Lin Wu, Yi-Heng Li
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Stress-induced alteration in endothelial cells (ECs) integrity precedes the development of atherosclerosis. Previous studies showed that the soluble recombinant thrombomodulin (rTM) not only increases ECs proliferation but also exerts anti-a
Externí odkaz:
https://doaj.org/article/8e8dabad06ad4d79a6b1dbca4e9c35df
Autor:
Gang Hui Lee, Po Ku Chen, Cheng Hsiang Kuo, Hua Lin Wu, Yi Hsun Huang, Ming Jer Tang, Guey Yueh Shi, Edward M. Conway
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41:1657-1671
Objective: VEGF (vascular endothelial growth factor) plays a critical role in physiological and pathological angiogenesis. Endothelial 3D podosomes (3DPs) are a type of F-actin-rich membrane microdomain, predominantly found in endothelial tip cells c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158dc65eb631cfe613506bb138b9d302
https://doi.org/10.1161/atvbaha.121.315931
https://doi.org/10.1161/atvbaha.121.315931
Autor:
Chao-Han Lai, Kuan-Chieh Wang, Fang-Tzu Lee, Hung-Wen Tsai, Chih-Yuan Ma, Tsung-Lin Cheng, Bi-Ing Chang, Yu-Jen Yang, Guey-Yueh Shi, Hua-Lin Wu
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146565 (2016)
Toll-like receptor (TLR) family plays a key role in innate immunity and various inflammatory responses. TLR4, one of the well-characterized pattern-recognition receptors, can be activated by endogenous damage-associated molecular pattern molecules su
Externí odkaz:
https://doaj.org/article/03e2820578674d28b5f8c1549945456c
Autor:
Yi-Hsun Huang, Ching-Chang I, Cheng-Hsiang Kuo, Yun-Yan Hsu, Fang-Tzu Lee, Guey-Yueh Shi, Sung-Huei Tseng, Hua-Lin Wu
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122491 (2015)
To determine the role of thrombomodulin (TM) in corneal epithelial wound healing, and to investigate whether recombinant TM epidermal growth factor-like domain plus serine/threonine-rich domain (rTMD23) has therapeutic potential in corneal epithelial
Externí odkaz:
https://doaj.org/article/ed4f17d909f3429dbb93968e56d33c67
Lewisy promotes migration of oral cancer cells by glycosylation of epidermal growth factor receptor.
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120162 (2015)
Aberrant glycosylation changes normal cellular functions and represents a specific hallmark of cancer. Lewisy (Ley) carbohydrate upregulation has been reported in a variety of cancers, including oral squamous cell carcinoma (OSCC). A high level of Le
Externí odkaz:
https://doaj.org/article/cdbf6f02f58c44e7a5a3730129f17a3c
Autor:
Ying Li Lin, Ting-Hsing Chao, Hua Lin Wu, Po Sheng Chen, Kuan Chieh Wang, Hsing Chun Chung, Ting Yu Huang, Yi-Heng Li, Shih Ya Tseng, Chawn Yau Luo, Guey Yueh Shi
Publikováno v:
Atherosclerosis. 287:54-63
Background and aims Thrombomodulin (TM) is an endothelial cell membrane-bound anticoagulant protein expressed in normal arteries. After vascular injury, medial and neointimal smooth muscle cells (SMCs) exhibit large amounts of TM. The purpose of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df2bdc764210512285ab49ebbc1e4bd
https://doi.org/10.1016/j.atherosclerosis.2019.05.019
https://doi.org/10.1016/j.atherosclerosis.2019.05.019
Autor:
Tsung-Lin Cheng, Chao-Han Lai, Shinn-Jong Jiang, Jui-Hsiang Hung, Shi-Kai Liu, Bi-Ing Chang, Guey-Yueh Shi, Hua-Lin Wu
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
Anoikis resistance allows metastatic tumor cells to survive in a homeless environment. Activation of epithelial growth factor receptor (EGFR) signaling is one of the key mechanisms for metastatic tumor cells to resist anoikis, yet the regulation mech
Externí odkaz:
https://doaj.org/article/435b8a5c33964d7c8a28b5aaff3963a5