STING induces HOIP-mediated synthesis of M1 ubiquitin chains to stimulate NFκB signaling.

Autor: Fischer TD; Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health; Bethesda, MD, USA., Bunker EN; Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health; Bethesda, MD, USA., Zhu PP; Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health; Bethesda, MD, USA., Guerroué FL; Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health; Bethesda, MD, USA., Hadjian M; Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health; Bethesda, MD, USA., Dominguez-Martin E; Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health; Bethesda, MD, USA., Scavone F; Department of Biochemistry and Molecular Biology, Colorado State University; Fort Collins, CO, USA., Cohen R; Department of Biochemistry and Molecular Biology, Colorado State University; Fort Collins, CO, USA., Yao T; Department of Biochemistry and Molecular Biology, Colorado State University; Fort Collins, CO, USA., Wang Y; Mass Spectrometry, National Institute of Dental and Craniofacial Research, National Institutes of Health; Bethesda, MD, USA., Werner A; Stem Cell Biochemistry Unit, National Institute of Dental and Craniofacial Research, National Institutes of Health; Bethesda, MD, USA., Youle RJ; Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health; Bethesda, MD, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 01. Date of Electronic Publication: 2024 Oct 01.