The associations of cholesterol metabolism and plasma plant sterols with all-cause and cardiovascular mortality[S]

Autor: Guenther Silbernagel, Guenter Fauler, Michael M. Hoffmann, Dieter Lütjohann, Bernhard R. Winkelmann, Bernhard O. Boehm, Winfried März

Publikováno v: Journal of Lipid Research, Vol 51, Iss 8, Pp 2384-2393 (2010)

Moderately elevated levels of plasma plant sterols have been suspected to be causally involved in atherosclerosis. The aim of this study was to investigate whether plant sterols and other markers of sterol metabolism predicted all-cause and cardiovas

Externí odkaz: https://doaj.org/article/c3c8338a639a46aea99f4af8b1920848

Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemias⃞

Autor: Adelheid Kratzer, Marlene Buchebner, Thomas Pfeifer, Tatjana M. Becker, Georg Uray, Makoto Miyazaki, Shinobu Miyazaki-Anzai, Birgit Ebner, Prakash G. Chandak, Rajendra S. Kadam, Emine Calayir, Nora Rathke, Helmut Ahammer, Branislav Radovic, Michael Trauner, Gerald Hoefler, Uday B. Kompella, Guenter Fauler, Moshe Levi, Sanja Levak-Frank, Gerhard M. Kostner, Dagmar Kratky

Publikováno v: Journal of Lipid Research, Vol 50, Iss 2, Pp 312-326 (2009)

Liver X receptors (LXRs) are important regulators of cholesterol and lipid metabolism. LXR agonists have been shown to limit the cellular cholesterol content by inducing reverse cholesterol transport, increasing bile acid production, and inhibiting i

Externí odkaz: https://doaj.org/article/6a1e1a9cda944a8a9646f076b4b3f93a

Condensation of delta-1-piperideine-6-carboxylate with ortho-aminobenzaldehyde allows its simple, fast, and inexpensive quantification in the urine of patients with antiquitin deficiency

Autor: Bernd Jilma, Thomas Boehm, Barbara Plecko, Karin Petroczi, Holger Hubmann, Déborah Mathis, E.A. Struys, Kristaps Klavins, Guenter Fauler

Publikováno v: Boehm, T, Hubmann, H, Petroczi, K, Mathis, D, Klavins, K, Fauler, G, Plecko, B, Struys, E & Jilma, B 2020, ' Condensation of delta-1-piperideine-6-carboxylate with ortho-aminobenzaldehyde allows its simple, fast, and inexpensive quantification in the urine of patients with antiquitin deficiency ', Journal of Inherited Metabolic Disease, vol. 43, no. 4, pp. 891-900 . https://doi.org/10.1002/jimd.12214
Journal of Inherited Metabolic Disease
Journal of Inherited Metabolic Disease, 43(4), 891-900. Springer Netherlands

Antiquitin (ATQ) deficiency leads to tissue, plasma, and urinary accumulation of alpha‐aminoadipic semialdehyde (AASA) and its Schiff base delta‐1‐piperideine‐6‐carboxylate (P6C). Although genetic testing of ALDH7A1 is the most definitive d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5230eabdd53708a727f0334326088f
https://research.vumc.nl/en/publications/6e5b13db-e887-4266-93aa-19de91303b8a

Neuroblastoma causes alterations of the intestinal microbiome, gut hormones, inflammatory cytokines, and bile acid composition

Autor: Christoph, Castellani, Georg, Singer, Margarita, Kaiser, Thomas, Kaiser, Jianfeng, Huang, Daniela, Sperl, Karl, Kashofer, Guenter, Fauler, Barbara, Guertl-Lackner, Gerald, Höfler, Holger, Till

Publikováno v: Pediatric bloodcancer. 64(8)

To assess the effect of neuroblastoma (NB) on the intestinal microbiome, metabolism, and inflammatory parameters in a murine model.Athymic Hsd:Fox1nu mice received subperitoneal implantation of human NB cells (MHH-NB11) (tumor group, TG) or culture m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::231ef0d2497e2510118593f363b2b498
https://pubmed.ncbi.nlm.nih.gov/28074537

Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia

Autor: Georg Uray, Branislav Radovic, Thomas Pfeifer, Nora Rathke, Uday B. Kompella, Rajendra S. Kadam, Dagmar Kratky, Makoto Miyazaki, Sanja Levak-Frank, Gerhard M. Kostner, Shinobu Miyazaki-Anzai, Birgit Ebner, Helmut Ahammer, Prakash G. Chandak, Gerald Hoefler, Emine Calayir, Adelheid Kratzer, Guenter Fauler, Marlene Buchebner, Moshe Levi, Michael Trauner, Tatjana Becker

Publikováno v: Journal of Lipid Research, Vol 50, Iss 2, Pp 312-326 (2009)
Journal of Lipid Research

Liver X receptors (LXRs) are important regulators of cholesterol and lipid metabolism. LXR agonists have been shown to limit the cellular cholesterol content by inducing reverse cholesterol transport, increasing bile acid production, and inhibiting i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004f673b0acd7d9a7c29a98d3b1791df
https://doi.org/10.1194/jlr.m800376-jlr200