Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Guennadi Kozlov"'
Autor:
Guennadi Kozlov, Jianning Jiang, Tyler Rutherford, Anne M. Noronha, Christopher J. Wilds, Kalle Gehring
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 7-16 (2024)
La-related proteins (LARPs) are a family of RNA-binding proteins that share a conserved La motif (LaM) domain. LARP1 plays a role in regulating ribosomal protein synthesis and stabilizing mRNAs and has a unique structure without an RNA binding RRM do
Externí odkaz:
https://doaj.org/article/6b6546ccc14b42b59f428ad7279add2a
Autor:
Luba Mahbub, Guennadi Kozlov, Pengyu Zong, Emma L Lee, Sandra Tetteh, Thushara Nethramangalath, Caroline Knorn, Jianning Jiang, Ashkan Shahsavan, Lixia Yue, Loren Runnels, Kalle Gehring
Publikováno v:
eLife, Vol 12 (2023)
Cystathionine-β-synthase (CBS)-pair domain divalent metal cation transport mediators (CNNMs) are an evolutionarily conserved family of magnesium transporters. They promote efflux of Mg2+ ions on their own and influx of divalent cations when expresse
Externí odkaz:
https://doaj.org/article/936846b136cd4ffd8569d36738791439
Autor:
Yu Seby Chen, Guennadi Kozlov, Brandon E. Moeller, Ahmed Rohaim, Rayan Fakih, Benoît Roux, John E. Burke, Kalle Gehring
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
CNNM/CorB proteins are a conserved family of membrane proteins associated with Mg2+ transport. Here, structures of an archaeal CorB protein in apo state and with Mg2+-ATP bound and accompanying biophysical experiments suggest direct Mg2+ transport by
Externí odkaz:
https://doaj.org/article/9173b3bf4c7d453b84ee3eb1b8577812
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract The phosphatases of regenerating liver (PRLs) are involved in tumorigenesis and metastatic cancer yet their cellular function remains unclear. Recent reports have shown PRL phosphatases bind tightly to the CNNM family of membrane proteins to
Externí odkaz:
https://doaj.org/article/0fb93675d99f4329802dc664671cbeb7
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0166643 (2016)
Salmonella Typhimurium GtgE is an effector protein contributing to the virulence of this pathogen. It was shown to possess highly selective proteolytic activity against a subset of Rab proteins that helps in evasion of Salmonella-containing vacuole (
Externí odkaz:
https://doaj.org/article/8a18386c49084101897ab2d629267d0a
Autor:
Xinlu Li, Marie Ménade, Guennadi Kozlov, Zheping Hu, Zheng Dai, Peter S McPherson, Bernard Brais, Kalle Gehring
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137298 (2015)
Sacsin is a large protein implicated in the neurodevelopmental and neurodegenerative disease autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), which features the loss of Purkinje neurons in the cerebellum. Although the domain archit
Externí odkaz:
https://doaj.org/article/8c0d8932f2fa4e679f381f9e71dac2b2
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-1 (2017)
A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper
Externí odkaz:
https://doaj.org/article/447c938499dd41cd8e9f8da85f7b9141
Autor:
Brigitte Ritter, Sebastian Murphy, Hatem Dokainish, Martine Girard, Manasa V Gudheti, Guennadi Kozlov, Marilene Halin, Jacynthe Philie, Erik M Jorgensen, Kalle Gehring, Peter S McPherson
Publikováno v:
PLoS Biology, Vol 11, Iss 10, p e1001670 (2013)
AP-2 is the core-organizing element in clathrin-mediated endocytosis. During the formation of clathrin-coated vesicles, clathrin and endocytic accessory proteins interact with AP-2 in a temporally and spatially controlled manner, yet it remains elusi
Externí odkaz:
https://doaj.org/article/83c6795f781d4dc4a2e3098549248965
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62021 (2013)
Protein disulfide isomerases comprise a large family of enzymes responsible for catalyzing the proper oxidation and folding of newly synthesized proteins in the endoplasmic reticulum (ER). Protein disulfide isomerase-related (PDIR) protein (also know
Externí odkaz:
https://doaj.org/article/bf6f78ade2154f57bcb92051dd8de185
Autor:
Tatiana Domitrovic, Guennadi Kozlov, João Claudio Gonçalves Freire, Claudio Akio Masuda, Marcius da Silva Almeida, Mónica Montero-Lomeli, Georgia Correa Atella, Edna Matta-Camacho, Kalle Gehring, Eleonora Kurtenbach
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11163 (2010)
The genome of Saccharomyces cerevisiae is arguably the best studied eukaryotic genome, and yet, it contains approximately 1000 genes that are still relatively uncharacterized. As the majority of these ORFs have no homologs with characterized sequence
Externí odkaz:
https://doaj.org/article/c5b8cf9dc65a48058925a8b9d9f949b0