How individual participant data meta-analyses have influenced trial design, conduct, and analysis

Autor: Tierney, J.F., Pignon, J.P., Gueffyier, F., Clarke, M., Askie, L., Vale, C.L., Burdett, S., Rovers, M.M.

Publikováno v: Journal of Clinical Epidemiology, 68, 11, pp. 1325-35
Journal of Clinical Epidemiology, 68, 1325-35

Contains fulltext : 152302.pdf (Publisher’s version ) (Open Access) OBJECTIVES: To demonstrate how individual participant data (IPD) meta-analyses have impacted directly on the design and conduct of trials and highlight other advantages IPD might o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f15062ffce5628a04d767ed9e7ee14ea
https://hdl.handle.net/2066/152302

How individual participant data meta-analyses have influenced trial design, conduct, and analysis.

Autor: Tierney JF; MRC Clinical Trials Unit at UCL, Aviation House, 125 Kingsway, London WC2B 6NH, UK. Electronic address: jayne.tierney@ucl.ac.uk., Pignon JP; LNCC plateforme de méta-analyse en oncologie, Service de Biostatistique et d'Epidemiologie, Gustave-Roussy, Villejuif, France., Gueffyier F; Université Claude Bernard Lyon 1/Université de Lyon, 69365 Lyon Cedex 07, Lyon, France; Service de Pharmacologie Clinique, Hospices Civils de Lyon, Bron cedex, France., Clarke M; All-Ireland Hub for Trials Methodology Research, Queen's University Belfast, University Road, Belfast BT7 1NN, Northern Ireland, UK., Askie L; NHMRC Clinical Trials Centre, ABN 15 211 513 464, Locked Bag 77, Camperdown, NSW 1450 Australia., Vale CL; MRC Clinical Trials Unit at UCL, Aviation House, 125 Kingsway, London WC2B 6NH, UK., Burdett S; MRC Clinical Trials Unit at UCL, Aviation House, 125 Kingsway, London WC2B 6NH, UK.

Publikováno v: Journal of clinical epidemiology [J Clin Epidemiol] 2015 Nov; Vol. 68 (11), pp. 1325-35. Date of Electronic Publication: 2015 Jun 03.