Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gudrun Wahlström"'
Autor:
Olli Metsälä, Gudrun Wahlström, Pekka Taimen, Pirkko-Liisa Kellokumpu-Lehtinen, Johanna Schleutker
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1052 (2023)
Prostate cancer affects millions of men globally. The prostate cancer-associated gene ANO7 is downregulated in advanced prostate cancer, whereas benign tissue and low-grade cancer display varying expression levels. In this study, we assess the spatia
Externí odkaz:
https://doaj.org/article/ae8d275287724f63b618bc978a674155
Autor:
Heli K J Pessa, Dario Greco, Jouni Kvist, Gudrun Wahlström, Tapio I Heino, Petri Auvinen, Mikko J Frilander
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13215 (2010)
BackgroundThe U12-type spliceosome is responsible for the removal of a subset of introns from eukaryotic mRNAs. U12-type introns are spliced less efficiently than normal U2-type introns, which suggests a rate-limiting role in gene expression. The Dro
Externí odkaz:
https://doaj.org/article/260a911fd23640368f83c04f90b671be
Autor:
Gudrun Wahlström, Samuel Heron, Matias Knuuttila, Elina Kaikkonen, Nea Tulonen, Olli Metsälä, Christoffer Löf, Otto Ettala, Peter J Boström, Pekka Taimen, Matti Poutanen, Johanna Schleutker
Publikováno v:
Human Molecular Genetics. 31:2063-2077
Prostate cancer is among the most common cancers in men, with a large fraction of the individual risk attributable to heritable factors. A majority of the diagnosed cases does not lead to a lethal disease, and hence biological markers that can distin
Autor:
Elina, Kaikkonen, Tommi, Rantapero, Qin, Zhang, Pekka, Taimen, Virpi, Laitinen, Markku, Kallajoki, Dhanaprakash, Jambulingam, Otto, Ettala, Juha, Knaapila, Peter J, Boström, Gudrun, Wahlström, Csilla, Sipeky, Juha-Pekka, Pursiheimo, Teuvo, Tammela, Pirkko-Liisa, Kellokumpu-Lehtinen, Vidal, Fey, Lovise, Maehle, Fredrik, Wiklund, Gong-Hong, Wei, Johanna, Schleutker
Publikováno v:
International Journal of Cancer
Prostate cancer is one of the most common and heritable human cancers. Our aim was to find germline biomarkers that can predict disease outcome. We previously detected predisposing signals at 2q37, the location of the prostate specific ANO7 gene. To
Publikováno v:
Mechanisms of Development. 121:1377-1391
The single copy Drosophila alpha-actinin gene is alternatively spliced to generate three different isoforms that are expressed in larval muscle, adult muscle and non-muscle cells, respectively. We have generated novel alpha-actinin alleles, which spe
Autor:
Xiaojuan Meng, Meelis Kolmer, Mika Tirronen, Gudrun Wahlström, Christophe Roos, Tiina Immonen, Reinhard Predel, Tapio I. Heino, Hannu Sariola, Nisse Kalkkinen
Publikováno v:
Mechanisms of Development. 117:5-13
In a genomic screen we isolated the Drosophila gene hugin (hug, cytology 87C1-2) by cross-hybridisation to a human glial cell line-derived neurotrophic factor cDNA. Upon cDNA sequence analysis and in vitro expression assays, the hugin gene was found
Autor:
Gudrun Wahlström, Tapio I. Heino, Pieta K. Mattila, Pekka Lappalainen, Maria K. Vartiainen, Lumi Yamamoto
Publikováno v:
The Journal of Cell Biology
The actin cytoskeleton is essential for cellular remodeling and many developmental and morphological processes. Twinfilin is a ubiquitous actin monomer–binding protein whose biological function has remained unclear. We discovered and cloned the Dro
Autor:
Terhi Karpanen, Tapio I. Heino, Kari Alitalo, Gudrun Wahlström, Christophe Roos, Mari-Anne Pulkkinen, Ulf Eriksson
Publikováno v:
Mechanisms of Development. 109:69-77
Several signalling pathways have been defined by studies of genes originally characterised in Drosophila. However, some mammalian signalling systems have so far escaped discovery in the fly. Here, we describe the identification and characterisation o
Autor:
F A Rainey, Per E. J. Saris, Mirja Salkinoja-Salonen, Gudrun Wahlström, Tuija S.M. Pirttijärvi
Publikováno v:
Journal of Industrial Microbiology & Biotechnology. 26:107-114
The properties of Bacillus coagulans and of other bacilli that contaminate paper and paperboard manufacturing processes were investigated under simulated industrial conditions. Nisin (0.05 to 0.125 μ2g ml−1) blocked growth of indigenous bacilli th
Publikováno v:
DNA Sequence. 9:245-261
The sequences of the left end of the nisin-sucrose transposon Tn5481 in Lactococcus la& subsp. Zuctis NS, the adjacent 1.5 kb chromosomal region upstream of the junction site as well as a 5.0 kb region downstream of the nisZBTCIPRKFEG enes wnstreamwi