Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gudrun Pfaffinger"'
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Helicobacter pylori is a Gram-negative bacterial carcinogenic pathogen that infects the stomachs of half of the human population. It is a natural mutator due to a deficient DNA mismatch repair pathway and is naturally competent for transform
Externí odkaz:
https://doaj.org/article/c33911a13f4b41d782f37a716eebbc58
Autor:
Florent Ailloud, Xavier Didelot, Sabrina Woltemate, Gudrun Pfaffinger, Jörg Overmann, Ruth Christiane Bader, Christian Schulz, Peter Malfertheiner, Sebastian Suerbaum
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Helicobacter pylori, a bacterial pathogen that infects human stomachs, has high genetic diversity across hosts. Here, Ailloud et al. reveal genetic structuring of H. pylori populations among different stomach regions of individual hosts and find sign
Externí odkaz:
https://doaj.org/article/9a3e48a0d62246e483c72c41e2e85902
Autor:
Eva Rothmeier, Gudrun Pfaffinger, Christine Hoffmann, Christopher F Harrison, Heinrich Grabmayr, Urska Repnik, Mandy Hannemann, Stefan Wölke, Andreas Bausch, Gareth Griffiths, Annette Müller-Taubenberger, Aymelt Itzen, Hubert Hilbi
Publikováno v:
PLoS Pathogens, Vol 9, Iss 9, p e1003598 (2013)
The causative agent of Legionnaires' disease, Legionella pneumophila, uses the Icm/Dot type IV secretion system (T4SS) to form in phagocytes a distinct "Legionella-containing vacuole" (LCV), which intercepts endosomal and secretory vesicle traffickin
Externí odkaz:
https://doaj.org/article/d07c7a3b704a42c68c0a2d751c0ab39e
Autor:
Gudrun Pfaffinger, Jörg Overmann, Christian Schulz, Sabrina Woltemate, Ruth Christiane Bader, Florent Ailloud, Sebastian Suerbaum, Xavier Didelot, Peter Malfertheiner
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The human pathogen Helicobacter pylori displays extensive genetic diversity. While H. pylori is known to evolve during infection, population dynamics inside the gastric environment have not been extensively investigated. Here we obtained gastric biop
Autor:
Bernhard Holzmann, Rudolf Haase, Klaus Ruckdeschel, Georg Häcker, Andreas Sing, Gudrun Pfaffinger, Jürgen Heesemann, Heike Weighardt
Publikováno v:
The Journal of Immunology. 173:3320-3328
TLRs are important sensors of the innate immune system that serve to identify conserved microbial components to mount a protective immune response. They furthermore control the survival of the challenged cell by governing the induction of pro- and an
Autor:
Andreas Otto, Ivo Finsel, Christine Hoffmann, Eva Rothmeier, Hubert Hilbi, Gudrun Pfaffinger, Dörte Becher, Michael Hecker
Publikováno v:
Cellular Microbiology.
Summary The opportunistic pathogen Legionella pneumophila employs the Icm/Dot type IV secretion system and ∼300 different effector proteins to replicate in macrophages and amoebae in a distinct ‘Legionella-containing vacuole’ (LCV). LCVs from i
Autor:
Christine, Hoffmann, Ivo, Finsel, Andreas, Otto, Gudrun, Pfaffinger, Eva, Rothmeier, Michael, Hecker, Dörte, Becher, Hubert, Hilbi
Publikováno v:
Cellular microbiology. 16(7)
The opportunistic pathogen Legionella pneumophila employs the Icm/Dot type IV secretion system and ∼300 different effector proteins to replicate in macrophages and amoebae in a distinct 'Legionella-containing vacuole' (LCV). LCVs from infected RAW
Autor:
Gudrun Pfaffinger, Heinrich Grabmayr, Eva Rothmeier, Aymelt Itzen, Stefan Wölke, Mandy Hannemann, Gareth Griffiths, Hubert Hilbi, Andreas R. Bausch, Urska Repnik, Christopher F. Harrison, Annette Müller-Taubenberger, Christine Hoffmann
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 9, Iss 9, p e1003598 (2013)
PLoS Pathogens, Vol 9, Iss 9, p e1003598 (2013)
The causative agent of Legionnaires' disease, Legionella pneumophila, uses the Icm/Dot type IV secretion system (T4SS) to form in phagocytes a distinct “Legionella-containing vacuole” (LCV), which intercepts endosomal and secretory vesicle traffi
Autor:
Konrad Trülzsch, Gerhardt Zenner, Kathleen Richter, Klaus Ruckdeschel, Gudrun Pfaffinger, Jürgen Heesemann, Martin Aepfelbacher
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 176(10)
Pathogenic Yersinia spp. neutralize host defense mechanisms by engaging a type III protein secretion system that translocates several Yersinia outer proteins (Yops) into the host cell. Although the modulation of the cellular responses by individual Y
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 175(12)
Pathogenic Yersinia spp. use a panel of virulence proteins that antagonize signal transduction processes in infected cells to undermine host defense mechanisms. One of these proteins, Yersinia enterocolitica outer protein P (YopP), down-regulates the