Intervention in autism based on Early Start Denver Model in a multiethnic immigrant setting—experiences of preschool staff involved in its implementation

Autor: Petra Linnsand, Gudrun Nygren, Jonas Hermansson, Christopher Gillberg, Emilia Carlsson

Publikováno v: Frontiers in Child and Adolescent Psychiatry, Vol 3 (2024)

BackgroundEarly interventions for young children with autism have been shown to enhance developmental outcomes. However, opportunities for targeted interventions in autism, both in care and preschool, are often lacking, particularly in immigrant comm

Externí odkaz: https://doaj.org/article/a21469bfefb74b678da3061cc3196b67

Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders.

Autor: Claire S Leblond, Jutta Heinrich, Richard Delorme, Christian Proepper, Catalina Betancur, Guillaume Huguet, Marina Konyukh, Pauline Chaste, Elodie Ey, Maria Rastam, Henrik Anckarsäter, Gudrun Nygren, I Carina Gillberg, Jonas Melke, Roberto Toro, Beatrice Regnault, Fabien Fauchereau, Oriane Mercati, Nathalie Lemière, David Skuse, Martin Poot, Richard Holt, Anthony P Monaco, Irma Järvelä, Katri Kantojärvi, Raija Vanhala, Sarah Curran, David A Collier, Patrick Bolton, Andreas Chiocchetti, Sabine M Klauck, Fritz Poustka, Christine M Freitag, Regina Waltes, Marnie Kopp, Eftichia Duketis, Elena Bacchelli, Fiorella Minopoli, Liliana Ruta, Agatino Battaglia, Luigi Mazzone, Elena Maestrini, Ana F Sequeira, Barbara Oliveira, Astrid Vicente, Guiomar Oliveira, Dalila Pinto, Stephen W Scherer, Diana Zelenika, Marc Delepine, Mark Lathrop, Dominique Bonneau, Vincent Guinchat, Françoise Devillard, Brigitte Assouline, Marie-Christine Mouren, Marion Leboyer, Christopher Gillberg, Tobias M Boeckers, Thomas Bourgeron

Publikováno v: PLoS Genetics, Vol 8, Iss 2, p e1002521 (2012)

Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders with a complex inheritance pattern. While many rare variants in synaptic proteins have been identified in patients with ASD, little is known about their effects

Externí odkaz: https://doaj.org/article/03767000fd224a4884ce09193bcfd6c7

Identification of pathway-biased and deleterious melatonin receptor mutants in autism spectrum disorders and in the general population.

Autor: Pauline Chaste, Nathalie Clement, Oriane Mercati, Jean-Luc Guillaume, Richard Delorme, Hany Goubran Botros, Cécile Pagan, Samuel Périvier, Isabelle Scheid, Gudrun Nygren, Henrik Anckarsäter, Maria Rastam, Ola Ståhlberg, Carina Gillberg, Emilie Serrano, Nathalie Lemière, Jean Marie Launay, Marie Christine Mouren-Simeoni, Marion Leboyer, Christopher Gillberg, Ralf Jockers, Thomas Bourgeron

Publikováno v: PLoS ONE, Vol 5, Iss 7, p e11495 (2010)

Melatonin is a powerful antioxidant and a synchronizer of many physiological processes. Alteration of the melatonin pathway has been reported in circadian disorders, diabetes and autism spectrum disorders (ASD). However, very little is known about th

Externí odkaz: https://doaj.org/article/db5bfbc334f143c8acb3c470126be6b5

A High Prevalence of Autism Spectrum Disorder in Preschool Children in an Immigrant, Multiethnic Population in Sweden: Challenges for Health Care

Autor: Petra Linnsand, Åsa Nilses, Gudrun Nygren, Christopher Gillberg, Bibbi Hagberg

Publikováno v: Journal of Autism and Developmental Disorders

This study examines the prevalence of autism spectrum disorder (ASD) in preschool children in an immigrant population. Possible risk factors for ASD and individual needs for the children and their families are described, as well as implications for h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be47157d41289383238672238460ca45
https://doi.org/10.1007/s10803-020-04563-8

Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism

Autor: Jochen C. Meier, Terence Neil Dear, Richard Delorme, Pascal Legendre, Jing Bai, Coralie Fassier, Gudrun Nygren, Elsa Delaby, Marion Leboyer, Marion Pilorge, S. De Gois, Jamilé Hazan, H. Le Corronc, H. Cheval, A. Potey, Satoru Otani, Vincent Guinchat, Brigitte Assouline, Maya Topf, Sophie Gautron, Catalina Betancur, Bruno Giros, Françoise Devillard, Christopher Gillberg, Victoria M. James, Maria Råstam, Robert J. Harvey

Publikováno v: Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2016, 21 (7), pp.936-945 ⟨10.1038/mp.2015.139⟩
Molecular Psychiatry, 2016, 21 (7), pp.936-945 ⟨10.1038/mp.2015.139⟩

International audience; Autism spectrum disorder (ASD) is a common neurodevelopmental condition characterized by marked genetic heterogeneity. Recent studies of rare structural and sequence variants have identified hundreds of loci involved in ASD, b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d24e751cdb6d7e3469339518d2e7e13
https://www.hal.inserm.fr/inserm-01211157