Multicenter clinical evaluation of alinity m HCV assay performance

Autor: Stéphane Chevaliez, Francesco Onelia, Monia Pacenti, Emily Goldstein, Juan-Carlos Galán, Laura Martínez-García, Alba Vilas, Allison Glass, Leana Maree, Maria Krügel, Robert Ehret, Heribert Knechten, Patrick Braun, Gudrun Naeth, Sara Bonanzinga, Kathy Jackson, Klara Abravaya, Jens Dhein, Shihai Huang, Ajith M. Joseph, Danijela Lucic, Natalia Marlowe, Michael J. Palm, Karin Pfeifer, Dan Toolsie, Birgit Reinhardt, Martin Obermeier, Rory Gunson

Publikováno v: Journal of Clinical Virology
Journal of Clinical Virology, Elsevier, 2020, 129, pp.104531-. ⟨10.1016/j.jcv.2020.104531⟩
Journal of Clinical Virology, 2020, 129, pp.104531-. ⟨10.1016/j.jcv.2020.104531⟩

International audience; Background: Nucleic acid testing is essential for the detection and quantification of HCV RNA in the diagnosis of HCV infection and treatment monitoring. The Alinity m HCV assay was recently developed by Abbott Molecular for r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6df7f9b4a812f7af3d5658254d699d8
https://hal.archives-ouvertes.fr/hal-03491380

Multicenter Evaluation of Two Next-Generation HIV-1 Quantitation Assays, Aptima Quant Dx and Cobas 6800, in Comparison to the RealTi m e HIV-1 Reference Assay

Autor: Carsten Tiemann, Jörg Fuhrmann, Robert Ehret, Gunnar Schalasta, Martin Daumer, Heribert Knechten, Christian Noah, Martin Obermeier, Frank Wiesmann, Patrick Braun, Eva Wolf, Gudrun Naeth, Rolf Kaiser

Publikováno v: Journal of Clinical Microbiology

High accuracy and precision at the lower end of quantification are crucial requirements of a modern HIV viral load (VL) assay, since some clinically relevant thresholds are located at 50 and 200 copies/ml. In this study, we compared the performance o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b26d212da705857509a41771b2bcc3d
https://doi.org/10.1128/jcm.00292-18

Variation analysis of six HCV viral load assays using low viremic HCV samples in the range of the clinical decision points for HCV protease inhibitors

Autor: Annemarie Berger, Patrick Braun, Christoph Sarrazin, Rolf Kaiser, Frank Wiesmann, Robert Ehret, Gudrun Naeth, Heribert Knechten

Publikováno v: Medical Microbiology and Immunology

In the range of clinical decision points for response-guided therapy of HCV, there is still insufficient data concerning the conformity of quantification results obtained by different assays and their correlation with the HPS/CTM v2 assay which was u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31a765864b75577beaeb41e7ffa1eac
https://pubmed.ncbi.nlm.nih.gov/25398515

Comparison of HIV-1 viral load assay performance in immunological stable patients with low or undetectable viremia

Autor: Robert Ehret, Patrick Braun, Annemarie Berger, Gudrun Naeth, Heribert Knechten, Frank Wiesmann

Publikováno v: Medical microbiology and immunology. 202(1)

The goal of antiretroviral therapy is reduction in morbidity and mortality via suppression of human immunodeficiency virus (HIV) viral load (VL) to undetectable levels. VL assay sensitivity has improved over time, but the reproducibility and clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40738324e1d99333f726aa175d3ca1b
https://pubmed.ncbi.nlm.nih.gov/22699843

Evaluation of two assays for the quantification of HIV and HCV in clinical routine

Autor: Gudrun Naeth, Heribert Knechten, Patrick Braun, B. Haase, Frank Wiesmann

Publikováno v: Journal of Clinical Virology. 70:S92

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c9d5a0ec7c4c9887afdaaaa231b7835
https://doi.org/10.1016/j.jcv.2015.07.214