Systemic versus free antibiotic delivery in preventing acute exogenous implant related infection in a rat model

Autor: Conrado Aparicio, Ramon B. Gustilo, Mats Bue, Andrew H. Schmidt, Richard F. Kyle, Ole Halfdan Larsen, Glen Hansen, Dean T. Tsukayama, Arick Sabin, Gudrun Mirick Mueller, Joan E. Bechtold, Scott B. Marston, Alexandra R. Armstrong, Bruce R. Lindgren

Publikováno v: Marston, S, Mueller, G M, Sabin, A, Hansen, G T, Lindgren, B, Aparicio, C, Armstrong, A R, Larsen, O H, Schmidt, A, Kyle, R, Gustilo, R, Tsukayama, D, Bechtold, J & Bue, M 2022, ' Systemic versus Free Antibiotic Delivery in Preventing Acute Exogenous Implant Related Infection in a Rat Model ', Journal of Orthopaedic Research, vol. 40, no. 2, pp. 429-438 . https://doi.org/10.1002/jor.25052

We studied systemic ceftriaxone, and free/local tobramycin and doxycycline in a controlled rat model representing a generic acute exogenous joint infection. We hypothesized that evidence of infection (quantitative colony forming units [CFU], qualitat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c77ead22978bc055c741cda41b1798
https://pubmed.ncbi.nlm.nih.gov/33913540