Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gudrun Köhl"'
Autor:
Axel Kleespies, Gudrun Köhl, Michael Friedrich, Anderson J. Ryan, Alan Barge, Karl-Walter Jauch, Christiane J. Bruns
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 10, Pp 957-966 (2005)
ZD6126 is a novel vascular-targeting agent that acts by disrupting the tubulin cytoskeleton of an immature tumor endothelium, leading to an occlusion of tumor blood vessels and a subsequent tumor necrosis. We wanted to evaluate ZD6126 in primary and
Externí odkaz:
https://doaj.org/article/c82c0203142f4da0a62ad693c296856c
Autor:
Joachim Glaesner, Elisabeth Naschberger, Christina Hackl, Andreas Hiergeist, Stefan Fichtner-Feigl, Rebecca Kesselring, André Gessner, Susanne Merkl, Michael Stürzl, Caroline Theresa Seebauer, Markus F. Neurath, Gudrun Köhl, HJ Schlitt, Roland S. Croner, Anja K. Wege, Stefan M. Brunner, Helmut Neumann, Edward K. Geissler
Publikováno v:
Cancer Cell. 29:684-696
Colorectal cancer (CRC) is associated with loss of epithelial barrier integrity, which facilitates the interaction of the immunological microenvironment with the luminal microbiome, eliciting tumor-supportive inflammation. An important regulator of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1cd3d4cfc1baa7a566b7b39c078d893
https://doi.org/10.1016/j.ccell.2016.03.014
https://doi.org/10.1016/j.ccell.2016.03.014
Autor:
Marina Kreutz, Stephan Schreml, Gudrun Köhl, Matthias Fante, Katharina T. Weiß, Mark Berneburg, Julia Schreml, Frank Haubner, Sonja Haverkampf
Publikováno v:
Experimental dermatology. 26(2)
Dysregulation of pH is a feature of both tumor growth and tissue repair. In tumors, microenvironmental changes, like in lactate metabolism, lead to altered intra- and extracellular pH (pHi , pHe ) and vice versa. In wounds, barrier disruption results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2fac4aa983167b6486c5e39df0a986e
https://pubmed.ncbi.nlm.nih.gov/27623507
https://pubmed.ncbi.nlm.nih.gov/27623507
Autor:
P von Breitenbuch, Edward K. Geissler, Markus Steinbauer, Markus Guba, Karl-Walter Jauch, Gudrun Köhl
Publikováno v:
Surgery. 138:882-887
Background Resection of liver neoplasms is believed to promote growth of residual intrahepatic neoplastic cells. As the effects of radiofrequency thermoablation (RFA) are still unknown, we aimed to compare the influence of RFA versus liver resection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb98d5b846bb525d5952b6837af5cf2b
https://doi.org/10.1016/j.surg.2005.05.006
https://doi.org/10.1016/j.surg.2005.05.006
Autor:
Anderson J. Ryan, Karl-Walter Jauch, Christiane J. Bruns, Gudrun Köhl, Axel Kleespies, Alan Barge, Michael Friedrich
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 10, Pp 957-966 (2005)
ZD6126 is a novel vascular-targeting agent that acts by disrupting the tubulin cytoskeleton of an immature tumor endothelium, leading to an occlusion of tumor blood vessels and a subsequent tumor necrosis. We wanted to evaluate ZD6126 in primary and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436d95964f645b67a5c9d1614bd287a1
Autor:
Karl-Walter Jauch, Markus Steinbauer, Grigore Cernaianu, Michaela Cetto, Werner Falk, Gudrun Köhl, Edward K. Geissler, Leoni A. Kunz-Schughart, Markus Guba
Publikováno v:
Clinical and Experimental Metastasis. 20:135-141
To develop effective therapeutic strategies aimed at treating tumor metastasis, critical steps in this process must be better understood. For this purpose we have established a new model to visualize and quantify early metastasis. Murine CT-26 colon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01c6df9543a5f32e6571de9e6963171e
https://doi.org/10.1023/a:1022618909921
https://doi.org/10.1023/a:1022618909921
Publikováno v:
Anticancer research. 30(10)
Beyond their primary field of application some well-established drugs exhibit antitumour effects in a variety of cancers. The aim of this study was to investigate the effects of the COX2 inhibitor celecoxib and the mTOR antagonist rapamycin on angios
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4345426bb0dd5dc31c56e71b844f2b7c
https://pubmed.ncbi.nlm.nih.gov/21036716
https://pubmed.ncbi.nlm.nih.gov/21036716
Autor:
Ivan Ischenko, Alan Barge, M. Yezhelyev, Claudius Conrad, Karl-Walter Jauch, Christiane J. Bruns, Anderson J. Ryan, Stephen R. Wedge, Markus Guba, Edward K. Geissler, Gudrun Köhl, Ulrich Wiegand
Publikováno v:
Anti-cancer drugs. 18(5)
ZD6474 is a novel, orally available inhibitor of vascular endothelial growth factor receptor kinase insert domain receptor/flk-1 tyrosine kinase activity with additional activity against the epidermal growth factor receptor-1 tyrosine kinase. The aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a06ef35724eb2374ec865472f0d111
https://pubmed.ncbi.nlm.nih.gov/17414626
https://pubmed.ncbi.nlm.nih.gov/17414626
Autor:
M. Guba, Gudrun Köhl, Edward K. Geissler, M. Yezhelyev, K.-W. Jauch, C. J. Bruns, H. Seeliger
Publikováno v:
Chirurgisches Forum 2005 ISBN: 3540248889
Despite current chemotherapies pancreatic cancer steadfastly remains refractory to treatment. Here we tested a new approach of combining antiangiogenic and standard cytotoxic therapy in a metastatic human pancreatic cancer nude mouse model. Nude athy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::064b16b40ca17987243e46fd1ee75e50
https://doi.org/10.1007/3-540-26560-0_46
https://doi.org/10.1007/3-540-26560-0_46
Rapamycin verhindert Abstossung und Tumorwachstum in einem Tumor-Transplantations-Modell in der Maus
Autor:
S. Richter, C Graeb, Gudrun Köhl, Marcus N. Scherer, Markus Guba, K. W. Jauch, A. Krömer, J. Andrassy, Edward K. Geissler
Publikováno v:
Deutsche Gesellschaft für Chirurgie ISBN: 9783540200277
Immunosuppressive therapy in transplantation remains rather unspecific with known side effects of a generally suppressed immune system. Studies provided clear evidence for an increased susceptibility for infections and also cancer in the immunosuppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8f30a90de531f53eef6cb1ab4e6d12a
https://doi.org/10.1007/978-3-642-18547-2_3
https://doi.org/10.1007/978-3-642-18547-2_3