Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gudrun Johannesdottir"'
Autor:
Adalgeir, Arason, Bjarni A, Agnarsson, Gudrun, Johannesdottir, Oskar Th, Johannsson, Bylgja, Hilmarsdottir, Inga, Reynisdottir, Rosa B, Barkardottir
Publikováno v:
Genes
Mutations in BRCA1 result in predisposal to breast and ovarian cancers, but many variants exist with unknown clinical significance (VUS). One is BRCA1 c.4096+3A>G, which affects production of the full-length BRCA1 transcript, while augmenting transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1940fce6d79134d471755014d959d32
https://pubmed.ncbi.nlm.nih.gov/31683985
https://pubmed.ncbi.nlm.nih.gov/31683985
Autor:
Rosa B. Barkardottir, Gudrun Johannesdottir, Bjarni A. Agnarsson, Bylgja Hilmarsdottir, Adalgeir Arason, Óskar Þór Jóhannsson, Inga Reynisdottir
Publikováno v:
Genes, Vol 10, Iss 11, p 882 (2019)
Publisher's version (útgefin grein).
Mutations in BRCA1 result in predisposal to breast and ovarian cancers, but many variants exist with unknown clinical significance (VUS). One is BRCA1 c.4096+3A>G, which affects production of the full-length
Mutations in BRCA1 result in predisposal to breast and ovarian cancers, but many variants exist with unknown clinical significance (VUS). One is BRCA1 c.4096+3A>G, which affects production of the full-length
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638e3ce2b42266c469fa62404a75072f
https://doi.org/10.3390/genes10110882
https://doi.org/10.3390/genes10110882
Autor:
Haukur Gunnarsson, Thorbjorg Einarsdottir, Heli Nevanlinna, Åke Borg, Markus Ringnér, Rosa B. Barkardottir, Oskar Thor Johannsson, Johan Staaf, Johan Vallon-Christersson, Kristrun Olafsdottir, Adalgeir Arason, Göran Jönsson, Inga Reynisdottir, Berglind Osk Einarsdottir, Gudrun Johannesdottir, Rainer Fagerholm, Bjarni A. Agnarsson
Publikováno v:
Cancer Medicine
Cancer Medicine; 2(4), pp 437-446 (2013)
Cancer Medicine; 2(4), pp 437-446 (2013)
Amplification of 8p12-p11 is relatively common in breast cancer and several genes within the region have been suggested to affect breast tumor progression. The aim of the study was to map the amplified 8p12-p11 region in a large set of breast tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff2d3d3d6bd4043fb55e95c0f9314f8
http://europepmc.org/articles/PMC3799278
http://europepmc.org/articles/PMC3799278
Autor:
Heli Nevanlinna, Valgardur Egilsson, Gudrun Johannesdottir, Rosa B. Barkardottir, Adalgeir Arason, Bjarni A. Agnarsson, Hrefna Johannsdottir, Päivi Heikkilä, Håkan Olsson, Göran Jönsson, Oskar T. Johannsson, Åke Borg, Hannaleena Eerola
Publikováno v:
International Journal of Cancer. 119:1052-1060
Comparative genomic hybridization (CGH) analysis has shown that chromosome 5q deletions are the most frequent aberration in breast tumors from BRCA1 mutation carriers. To map the location of putative 5q tumor suppressor gene(s), 26 microsatellite mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ccce4cd5ae68c0d04efa2ab601ddff
https://doi.org/10.1002/ijc.21934
https://doi.org/10.1002/ijc.21934
Autor:
Robert Winqvist, Rosa B. Barkardottir, Bjarni A. Agnarsson, Aki Mustonen, Gudrun Johannesdottir, Oskar T. Johannsson, Kristján Jónasson, Beatrice Melin, Tuomas Heikkinen, Carl Blomqvist, Heli Nevanlinna, Haukur Gunnarsson, Adalgeir Arason, Kristiina Aittomäki, Göran Jönsson, Elizabeth M. Gillanders, Pål Møller, Åke Borg, Katri Pylkäs, Pär-Ola Bendahl
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research; 12(4) (2010)
Breast Cancer Research; 12(4) (2010)
Introduction: A significant proportion of high-risk breast cancer families are not explained by mutations in known genes. Recent genome-wide searches (GWS) have not revealed any single major locus reminiscent of BRCA1 and BRCA2, indicating that still
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e409eacd8c6a7f4f8ec9543940c321
http://lup.lub.lu.se/record/1831215
http://lup.lub.lu.se/record/1831215
Autor:
Rosa B. Barkardottir, Adalgeir Arason, Haukur Gunnarsson, Bjarni A. Agnarsson, Oskar T. Johannsson, Elizabeth M. Gillanders, Gudrun Johannesdottir
Publikováno v:
Journal of Negative Results in Biomedicine
Several mutations in the PALB2 gene (partner and localizer of BRCA2) have been associated with an increased risk of breast cancer, including a founder mutation, 1592delT, reported in Finnish breast cancer families. Although most often the risk is mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992be5ee8f50b36b17a90981d69897cc
https://doi.org/10.1186/1477-5751-7-5
https://doi.org/10.1186/1477-5751-7-5
Autor:
Adalgeir Arason, Johanna Schleutker, Hannele Erkko, Tarja Ikonen, Bjarni A. Agnarsson, Mads Thomassen, Anne-Marie Gerdes, Robert Winqvist, Torben A Kruse, Rosa B. Barkardottir, Katrin Rapakko, Gudrun Johannesdottir, Thomas Vognbjerg Sydenham, Mervi Grip, Åke Borg, Katja Backenhorn, Katri Pylkäs, Pål Møller, Sanna-Maria Karppinen, Juha Kere, Lauri A. Aaltonen, Kirsi Syrjäkoski, Anne Kallioniemi
Publikováno v:
Journal of medical genetics. 43(11)
Background: BARD1 was originally identified as a BRCA1-interacting protein but has also been described in tumour-suppressive functions independent of BRCA1. Several studies have indicated that the BARD1 gene is a potential target for germline changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484b525afcd7739b25ed247329954017
https://pubmed.ncbi.nlm.nih.gov/16825437
https://pubmed.ncbi.nlm.nih.gov/16825437
Autor:
Hrefna K, Johannsdottir, Gudrun, Johannesdottir, Bjarni A, Agnarsson, Hannaleena, Eerola, Adalgeir, Arason, Oskar T H, Johannsson, Päivi, Heikkilä, Valgardur, Egilsson, Hakan, Olsson, Ake, Borg, Heli, Nevanlinna, Rosa B, Barkardottir
Publikováno v:
Anticancer research. 24(5A)
Chromosomal aberrations in breast tumors from BRCA1 and BRCA2 germ-line mutation carriers are considerably more frequent than what is seen in sporadic breast tumors. According to Comparative Genomic Hybridisation analysis (CGH), deletions on chromoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dfa03d040d4121d3fe888b0780e14329
https://pubmed.ncbi.nlm.nih.gov/15521105
https://pubmed.ncbi.nlm.nih.gov/15521105
Autor:
Joan E. Bailey-Wilson, Jeffrey R. Smith, Adalgeir Arason, Kristrun R. Benediktsdottir, Jon Thor Bergthorsson, Gudrun Johannesdottir, Bjarni A. Agnarsson, Elizabeth M. Gillanders, Rosa B. Barkardottir, Jeff Trent
Publikováno v:
Scopus-Elsevier
Putative prostate cancer susceptibility loci have recently been identified by genetic linkage analysis on chromosomes 1q24–25 (HPC1), 1q44.2–43 (PCaP), and Xq27–28 (HPCX). In order to estimate the genetic linkage in Icelandic prostate cancer fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2bda344296d75945f5805afa0eeec6
https://pubmed.ncbi.nlm.nih.gov/11129338
https://pubmed.ncbi.nlm.nih.gov/11129338
Autor:
Gudrun Johannesdottir, Jon G. Jonasson, Rosa B. Barkardottir, Bjarni A. Agnarsson, I.B Björnsdottir, J Hallgrimsson, G Eiriksdottir, Julius Gudmundsson, H Sigurdsson, Sigurdur Ingvarsson, V. Egilsson
Publikováno v:
European journal of cancer (Oxford, England : 1990). 34(13)
Several chromosome regions exhibit loss of heterozygosity (LOH) in human breast carcinoma and are thought to harbour tumour suppressor genes (TSG). At chromosome 13q, two TSGs have been identified, RB1 at 13q14 and BRCA2 at 13q12-q13. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744c4cb92720cf40d488ea3337908baa
https://pubmed.ncbi.nlm.nih.gov/10070314
https://pubmed.ncbi.nlm.nih.gov/10070314