Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Gudrun Huper"'
Autor:
Craig B Bennett, Tammy J Westmoreland, Carmel S Verrier, Carrie A B Blanchette, Tiffany L Sabin, Hemali P Phatnani, Yuliya V Mishina, Gudrun Huper, Alice L Selim, Ernest R Madison, Dominique D Bailey, Adebola I Falae, Alvaro Galli, John A Olson, Arno L Greenleaf, Jeffrey R Marks
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1448 (2008)
BRCA1 has been implicated in numerous DNA repair pathways that maintain genome integrity, however the function responsible for its tumor suppressor activity in breast cancer remains obscure. To identify the most highly conserved of the many BRCA1 fun
Externí odkaz:
https://doaj.org/article/4bc481118f46427cb111886447c1d4de
Autor:
Jeffrey R. Marks, Gudrun Huper
Supplementary Data from Isogenic Normal Basal and Luminal Mammary Epithelial Isolated by a Novel Method Show a Differential Response to Ionizing Radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12eb3d950016666f5c60a5fef4184038
https://doi.org/10.1158/0008-5472.22370948
https://doi.org/10.1158/0008-5472.22370948
Autor:
Gudrun Huper, Jeffrey R. Marks
Publikováno v:
Cancer Research. 67:2990-3001
Epithelial cells within the normal breast duct seem to be the primary target for neoplastic transformation events that eventually produce breast cancer. Normal epithelial cells are easily isolated and propagated using standard techniques. However, th
Autor:
H. Frank, Liselotte Pister, Gerhard Hunsmann, Volker Moennig, R. W. Green, Joel H. Shaper, Dani P. Bolognesi, Gudrun Huper, Jens Lange, Werner Schäfer, Ronald B. Luftig, A. Demsey
New features in the architecture of mammalian type C viruses, in particular knoblike surface projections and hexagonally arranged subunits on the core shell could be demonstrated by electron microscopy, taking advantage of newly developed preparation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adf35c9635d9e3933d523e4d7a5b87ac
https://doi.org/10.1159/000397568
https://doi.org/10.1159/000397568
Publikováno v:
Oncogene. 24:2705-2714
Treatment of the breast cancer cell line, MDAMB468 with the DNA methylation inhibitor, 5-azacytidine (5-AzaC) results in growth arrest, whereas the growth of the normal breast epithelial line DU99 (telomerase immortalized) is relatively unaffected. C
Autor:
Wilfred Saito, Tammy J. Westmoreland, Craig B. Bennett, John A. Olson, Jeffrey R. Marks, Gudrun Huper
Publikováno v:
Journal of Surgical Research. 113:62-73
Background Heterologous expression of the tumor suppressor BRCA1 in the yeast Saccharomyces cerevisiae is lethal. To identify potential new BRCA1-interacting gene targets, we characterized highly conserved ionizing radiation (IR) sensitive gene delet
Publikováno v:
Breast Cancer Research and Treatment. 34:253-263
Ductal carcinoma in situ (intraductal carcinoma) of the breast is a commonly recognized and curable clinical entity. Patients with intraductal carcinoma are at risk to develop invasive breast cancer presumably due to a transition from the noninvasive
Autor:
Margaret A. Deutsch, William J. Fulkerson, Wayne M. Samuelson, Jeffrey C. Pence, Gudrun Huper, Richard K. Dodge, K B S Lyndon Jordan Iii, M M T Billie-Jo Kerns, Robert C. Bast, Charles A. Plate, J. Dirk Iglehart, Walter G. Wolfe
Publikováno v:
Cancer. 70:1115-1123
The monoclonal antibody 4B5 binds to a mucin-like antigen elaborated by respiratory epithelium of patients with non-small cell bronchogenic carcinoma. Several immunoassay formats were used to determine the presence of the antigen in lavage specimens.
Autor:
Nicholas M. Brown, Timothy T. Stenzel, Jerry Henslee, Gudrun Huper, Paula N Friedman, Jeffrey R. Marks
Publikováno v:
Breast Cancer Research and Treatment. 97
Genes that are expressed in a highly tissue- or disease-specific manner provide possible targets for therapeutics, early detection of cancer, and monitoring of disease burden during and after treatment. Further, genes of this type that code for secre
Publikováno v:
Molecular cancer research : MCR. 2(8)
TAFII70, a member of the basal transcription complex implicated in p53-mediated transcription, is synthesized as several alternately spliced variants. The predominant forms found in normal and neoplastic breast epithelial cells are shown to be 72 kDa