Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Gudrun Hefner"'
Autor:
Luzie Eichentopf, Christoph Hiemke, Andreas Conca, Jan Engelmann, Manfred Gerlach, Ursula Havemann-Reinecke, Gudrun Hefner, Vincenzo Florio, Maxim Kuzin, Klaus Lieb, Margareta Reis, Thomas G. Riemer, Alessandro Serretti, Georgios Schoretsanitis, Gerald Zernig, Gerhard Gründer, Xenia M. Hart
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
IntroductionA titration within a certain therapeutic reference range presupposes a relationship between the blood concentration and the therapeutic effect of a drug. However, this has not been systematically investigated for escitalopram. Furthermore
Externí odkaz:
https://doaj.org/article/d11abfae948b48b08146a8a3d4e2d368
Autor:
Michael Marschollek, Harald Binder, Klaus Kaier, Jan Wolff, Gudrun Hefner, Claus Normann, Katharina Domschke, Christoph Hiemke, Ansgar Klimke
Publikováno v:
BMJ Open, Vol 11, Iss 4 (2021)
Objectives The aim was to use routine data available at a patient’s admission to the hospital to predict polypharmacy and drug–drug interactions (DDI) and to evaluate the prediction performance with regard to its usefulness to support the efficie
Externí odkaz:
https://doaj.org/article/517321b71d3b46e3a9d6c0cfeaed0620
Autor:
Jan Wolff, Pamela Reißner, Gudrun Hefner, Claus Normann, Klaus Kaier, Harald Binder, Christoph Hiemke, Sermin Toto, Katharina Domschke, Michael Marschollek, Ansgar Klimke
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0255192 (2021)
IntroductionThe aim of this study was to describe the number and type of drugs used to treat depressive disorders in inpatient psychiatry and to analyse the determinants of potential drug-drug interactions (pDDI) and potentially inappropriate medicat
Externí odkaz:
https://doaj.org/article/b223070b369c4631a898dc5665c88fd9
Autor:
Nicole Moschny, Gudrun Hefner, Renate Grohmann, Gabriel Eckermann, Hannah B Maier, Johanna Seifert, Johannes Heck, Flverly Francis, Stefan Bleich, Sermin Toto, Catharina Meissner
Publikováno v:
Pharmaceuticals, Vol 14, Iss 6, p 514 (2021)
Both inflammation and smoking can influence a drug’s pharmacokinetic properties, i.e., its liberation, absorption, distribution, metabolism, and elimination. Depending on, e.g., pharmacogenetics, these changes may alter treatment response or cause
Externí odkaz:
https://doaj.org/article/be9fd6700ae04b21ba7933fa738d480d
Publikováno v:
Journal of Clinical Psychopharmacology. 42:317-320
Publikováno v:
Journal of neural transmission (Vienna, Austria : 1996). 129(11)
Off-label drug prescribing in psychiatry is increasing. Many psychotropic drugs are approved for psychopathologic syndromes rather than based on international standard diagnostic classification systems which might facilitate the clinical decision for
Autor:
Sermin Toto, Ansgar Klimke, Sibylle C. Roll, Jan Wolff, Martina Hahn, Gudrun Hefner, Christoph Hiemke
Publikováno v:
Journal of Neural Transmission. 128:263-272
Due to the high number of psychotropic drugs with anticholinergic potential, patients taking psychotropic drugs are at high risk for anticholinergic adverse drug reactions (ADRs). The aim of this study was to analyze the prevalence and type of pharma
Autor:
Sermin Toto, Ansgar Klimke, Gudrun Hefner, Sibylle C. Roll, Christoph Hiemke, Martina Hahn, Jan Wolff
Publikováno v:
Journal of Neural Transmission. 128:243-252
At least 170 approved drugs are linked to QT prolongation, which can lead to serious adverse drug reactions (ADRs), such as Torsade de Pointes (TdP). The aim of this study was to analyze the prevalence and type of pharmacodynamic drug–drug interact
Autor:
Ansgar Klimke, Christoph Hiemke, Sermin Toto, Martina Hahn, Sibylle C. Roll, Jan Wolff, Gudrun Hefner
Publikováno v:
European Journal of Clinical Pharmacology. 77:331-339
Many psychotropic drugs are listed as potentially inappropriate medication (PIM) in the older population. Potentially inappropriate means that prescription of those drugs in older adults may cause significant harm. The objective of this study was to
Autor:
Julia C. Stingl, Georgios Schoretsanitis, Manfred Gerlach, Bernd Schoppek, Gabriela Zurek, Werner Steimer, Jose de Leon, Niels Bergemann, Alois Saria, E. Jaquenoud-Sirot, Andreas Conca, Karin Egberts, Markus J. Schwarz, Thomas Messer, Matthias Müller, Manfred Uhr, Sven Ulrich, Ursula Havemann-Reinecke, Carlos López-Jaramillo, Michael Paulzen, Pierre Baumann, Gerhard Gründer, Stefan Unterecker, Margarete Silva Gracia, Benedikt Stegmann, E Haen, Ger Janssen, Christine Greiner, Peter Riederer, Gudrun Hefner, Gerd Laux, Ana M. Díaz-Zuluaga, R. Waschgler, Rainald Mössner, Gerald Zernig, Renate Helmer, Gabriel Eckermann, Bruno Pfuhlmann, Hans-Willi Clement, Christoph Hiemke, Katharina Domschke
Publikováno v:
Psiquiatría Biológica. 27:83-95
Resumen Objetivo La Monitorizacion Terapeutica de Drogas (llamada en ingles TDM: therapeutic drug monitoring) combina la cuantificacion de las concentraciones de medicamentos en la sangre, la interpretacion farmacologica y las directrices de tratamie