Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Gudrun Fredrikson"'
Publikováno v:
FEBS Letters. 285:139-144
cDNAs encoding rat adipose tissue hormone-sensitive lipase were expressed in COS cells, under the control of the SV40 promoter to half the level in rat adipocytes, the richest native source of the enzyme. A cDNA lacking most of the long 5′-untransl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295a78cb49bbef96ed977eba91331189
https://doi.org/10.1016/0014-5793(91)80744-n
https://doi.org/10.1016/0014-5793(91)80744-n
Publikováno v:
Lipids. 25:254-259
Enzymatically active, detergent-solubilized purified hormone-sensitive lipase (HSL) was incorporated into phosphatidylcholine (PC) vesicles, using a detergent-dialysis procedure with small PC vesicles, obtained by sonication, as phospholipid source a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbdc815e41a7b845c62f6f541b1fe2b2
https://doi.org/10.1007/bf02544384
https://doi.org/10.1007/bf02544384
Autor:
Frank Sundler, Hindrik Mulder, Cecilia Holm, Anna Maria Hoffmann, Anders Bergh, Lena Stenson Holst, Gudrun Fredrikson
Publikováno v:
FEBS letters. 355(2)
Using in situ hybridization, hormone-sensitive lipase was found to be expressed in a stage-dependent manner in Sertoli cells of rat testis. No expression was found in Leydig cells but expression in spermatids could not be excluded. These results sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183304651b919fff2fda6026518cf5dc
https://pubmed.ncbi.nlm.nih.gov/7982484
https://pubmed.ncbi.nlm.nih.gov/7982484
Publikováno v:
FEBS Letters. 111:125-130
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f7620f4d2151533cd0984fcb169c63
https://doi.org/10.1016/0014-5793(80)80776-9
https://doi.org/10.1016/0014-5793(80)80776-9
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 876:288-293
The respective roles of monoacylglycerol lipase and hormone-sensitive lipase in the sequential hydrolysis of adipose tissue triacylglycerols have been examined. An adipose tissue preparation, containing both lipases in approximately the same proporti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc16b3916d6ef1750aa9e8d3f9a5ac86
https://doi.org/10.1016/0005-2760(86)90286-9
https://doi.org/10.1016/0005-2760(86)90286-9
Publikováno v:
Biochemical and Biophysical Research Communications. 148:99-105
A polyclonal rabbit antibody was used to detect hormone-sensitive lipase in rat organs other than white adipose tissue. Inhibition of tissue diacylglycerol lipase activity by the anti-hormone-sensitive lipase, and by NaF, Hg2+ and diisopropyl fluorop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef536918c99fa9a799fff8199edfc736
https://doi.org/10.1016/0006-291x(87)91081-3
https://doi.org/10.1016/0006-291x(87)91081-3
Publikováno v:
European Journal of Biochemistry. 125:245-249
Several properties of the cytosolic cholesterol ester hydrolase from bovine adrenal cortex were investigated and those properties were compared directly with those of the well-characterised hormone-sensitive lipase, the rate-limiting enzyme in adipos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6054ce97106e4be7d19b9f0a8f475dda
https://doi.org/10.1111/j.1432-1033.1982.tb06675.x
https://doi.org/10.1111/j.1432-1033.1982.tb06675.x
Autor:
Tova Rahn, Martin Ridderstråle, Vincent C. Manganiello, Per Belfrage, Hans Tornqvist, Gudrun Fredrikson, Eva Degerman
Publikováno v:
FEBS Letters. (2-3):314-318
Incubation of rat adipocytes with wortmannin, a potent and selective phosphatidylinositol 3-kinase (PI 3-kinase) inhibitor, completely blocked the antilipolytic action of insulin (IC50≈ 100 nM), the insulin-induced activation and phosphorylation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0f490e08795a411f6ab58ec6544b69
Publikováno v:
FEBS Letters. (2-3):234-238
The consensus pentapeptide GXSXG is found in virtually all lipases/esterases and generally contains the active site serine. The primary sequence of hormone-sensitive lipase contains a single copy of this pentapeptide, surrounding Ser-423. We have ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618ce246ad29fc654f4627ebdc0b6551
