Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gudrun Engels"'
Autor:
Bernardo S. Franklin, Christine Schmitt-Mabmunyo, Marco A. Ataide, Wolfgang Kastenmüller, Gudrun Engels, Juan F. Rodriguez-Alcazar, Natalio Garbi, Eicke Latz
Publikováno v:
The journal of immunology 202(2), 550-558 (2018). doi:10.4049/jimmunol.1800107
Charcot–Leyden crystals (CLCs) are Galectin-10 protein crystals that can form after eosinophils degranulate. CLCs can appear and persist in tissues from patients with eosinophilic disorders, such as asthma, allergic reactions, and fungal and helmin
Autor:
Jasmin E. Hanke, Karsten Hiller, Jan Gehlen, Eicke Latz, Axel Imhof, Maike Kreutzenbeck, Gudrun Engels, Florian Hoss, Magdalini Serefidou, Carl-Christian Kolbe, Matthew Mangan, Anette Christ, Romina Kaiser, Maximilian Rothe, Timo Hess, Mario A. Lauterbach, Susanne V. Schmidt
Publikováno v:
Immunity 51(6), 997-1011.e7 (2019). doi:10.1016/j.immuni.2019.11.009
Toll-like receptor (TLR) activation induces inflammatory responses in macrophages by activating temporally defined transcriptional cascades. Whether concurrent changes in the cellular metabolism that occur upon TLR activation influence the quality of
Autor:
Simone Hornemann, Gudrun Engels, Philip M. Hansbro, Matthew Mangan, Christoph Brenker, Terje Espevik, Martin Fricke, Ashraf Al-Amoudi, Bernardo S. Franklin, Andrew G. Jarnicki, Dominic De Nardo, Adriano Aguzzi, Bernadette Jones, Ann Marshak-Rothstein, Patricia Busto, Eicke Latz, Brian G. Monks, Sandra R Mirandola, Lukas Bossaller, Sebastian Zimmer, Andrea Stutz, Mark Nordhoff, Wolfgang Kastenmüller, Jacqueline M Ratter, Reinhold E. Schmidt
Publikováno v:
NATURE IMMUNOLOGY
Nature Immunology
Nature immunology 15(8), 727-737 (2014). doi:10.1038/ni.2913
Nature Immunology
Nature immunology 15(8), 727-737 (2014). doi:10.1038/ni.2913
Microbes or danger signals trigger inflammasome sensors, which induce polymerization of the adaptor ASC and the assembly of ASC specks. ASC specks recruit and activate caspase-1, which induces maturation of the cytokine interleukin 1β (IL-1β) and p
Autor:
Christian E. Elger, Susanne Schoch, Michael Majores, Albert J. Becker, Wolfgang Hartmann, Volker Schick, Gudrun Engels, Johannes Schramm
Publikováno v:
Brain Pathol
Balloon cells of distinct focal cortical dysplasias type IIb (FCD(IIb)) and giant cells of cortical tubers in tuberous sclerosis (TSC) constitute neuropathological hallmarks and cytological similarities. In TSC, frequent mutations in the TSC1 or TSC2
Autor:
Michael Majores, Gudrun Engels, Albert J. Becker, Marec von Lehe, Julia Snoei, Horst Urbach, Jana Fassunke
Publikováno v:
Neuropathology : official journal of the Japanese Society of Neuropathology. 29(2)
Leptomeningeal spread is a casual but conspicuous finding in both low- and high-grade gliomas. We hypothesized a compromised integrity of the glia limitans-basal lamina complex due to glycosylation defects by loss of protein-o-mannosyltransferase-1 (
Autor:
Matthias Simon, Volker Schick, Sylvia Spitoni, Ingmar Blümcke, Gudrun Engels, Christiane B. Knobbe, Christian E. Elger, Arend Koch, Albert J. Becker, Michael Majores
Publikováno v:
Acta neuropathologica. 112(6)
Focal cortical dysplasias (FCD) with Taylor-type balloon cells (FCD(IIb)) are frequently observed in biopsy specimens of patients with pharmacoresistant focal epilepsies. The molecular pathogenesis of FCD(IIb), which lack familial inheritance, is onl
Autor:
Christian E. Elger, Johannes Schramm, Gudrun Engels, Albert J. Becker, Michael Majores, Jana Fassunke, Ingmar Blümcke, Volker Schick
Publikováno v:
Acta neuropathologica. 110(6)
Glioneuronal lesions are frequently observed in biopsy specimens obtained from patients with pharmacoresistant epilepsies, comprising focal cortical dysplasias (FCD) and gangliogliomas. Recent findings point to the phosphoinositide 3-kinase (PI3K) pa
Publikováno v:
Scoliosis, Vol 2, Iss Suppl 1, p S29 (2007)
It is well documented that congenital scoliosis patientssuffering defects of segmentation, like unilateral unseg-mented bars, need early surgical treatment, as the deform-ity will malignantly progress [1]. Other similar caseshaving defects of formati