Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Gudrun, Walenda"'
Autor:
Eric Seidel, Gudrun Walenda, Clemens Messerschmidt, Benedikt Obermayer, Mirko Peitzsch, Paal Wallace, Rohini Bahethi, Taekyeong Yoo, Murim Choi, Petra Schrade, Sebastian Bachmann, Gerhard Liebisch, Graeme Eisenhofer, Dieter Beule, Ute I Scholl
Publikováno v:
Endocrine Connections, Vol 9, Iss 2, Pp 122-134 (2020)
Mitotane is the only drug approved for the therapy of adrenocortical carcinoma (ACC). Its clinical use is limited by the occurrence of relapse during therapy. To investigate the underlying mechanisms in vitro, we here generated mitotane-resistant cel
Externí odkaz:
https://doaj.org/article/78a57dbb9b3648b6a37704ee4da16d0f
Autor:
Annika Etges, Nicole Hellmig, Gudrun Walenda, Bassam G. Haddad, Jan-Philipp Machtens, Thomas Morosan, Lars Christian Rump, Ute I. Scholl
Publikováno v:
Nephron. 146:418-428
Introduction: Pseudohypoaldosteronism type II (PHA II) is a Mendelian disorder, featuring hyperkalemic acidosis and low plasma renin levels, typically associated with hypertension. Mutations in WNK1, WNK4, CUL3, and KLHL3 cause PHA II, with dominant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79f89e7694c570ddef227aba65c09624
https://doi.org/10.1159/000521626
https://doi.org/10.1159/000521626
Autor:
Gudrun Walenda, Khalid Abnaof, Sylvia Joussen, Steffen Meurer, Hubert Smeets, Björn Rath, Kurt Hoffmann, Holger Fröhlich, Martin Zenke, Ralf Weiskirchen, Wolfgang Wagner
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77656 (2013)
Transforming growth factor-beta 1 (TGF-β1) stimulates a broad range of effects which are cell type dependent, and it has been suggested to induce cellular senescence. On the other hand, long-term culture of multipotent mesenchymal stromal cells (MSC
Externí odkaz:
https://doaj.org/article/9b268ca9a72e48c5add602321f05448b
Autor:
Michael Lohmann, Gudrun Walenda, Hatim Hemeda, Sylvia Joussen, Wolf Drescher, Stefan Jockenhoevel, Gabriele Hutschenreuter, Martin Zenke, Wolfgang Wagner
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37839 (2012)
The regenerative potential declines upon aging. This might be due to cell-intrinsic changes in stem and progenitor cells or to influences by the microenvironment. Mesenchymal stem cells (MSC) raise high hopes in regenerative medicine. They are usuall
Externí odkaz:
https://doaj.org/article/64f8faca285e4251aa72465b5446504d
Publikováno v:
Endocrinology. 157(8)
We recently demonstrated that a recurrent gain-of-function mutation in a T-type calcium channel, CACNA1H(M1549V), causes a novel Mendelian disorder featuring early-onset primary aldosteronism and hypertension. This variant was found independently in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c88ef2045554c5868f0779a428f255
https://pubmed.ncbi.nlm.nih.gov/27258646
https://pubmed.ncbi.nlm.nih.gov/27258646
Autor:
Hatim Hemeda, Gudrun Walenda, Bernd Hoffmann, Rudolf Merkel, Rebekka K. Schneider, Wolfgang Wagner
Publikováno v:
Tissue Engineering Part C: Methods. 18:924-934
Cell culture in regenerative medicine needs to facilitate efficient expansion according to good manufacturing practice requirements. Human platelet lysate (HPL) can be used as a substitute for fetal calf serum without the risk of xenogeneic immune re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9ff065a44627ce5597ceb73726e8d1
https://doi.org/10.1089/ten.tec.2011.0541
https://doi.org/10.1089/ten.tec.2011.0541
Autor:
Martin Zenke, Carina Adamzyk, Ruth Knüchel, Thomas Hieronymus, Mónica S. Ventura Ferreira, Wolfgang Wagner, Albrecht M. Müller, Sabine Neuss, Norina Labude, Gudrun Walenda, Willi Jahnen-Dechent, Daniela Piroth
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 7:944-954
Cord blood-derived haematopoietic stem cells (CB-HSCs) are an attractive source for transplantation in haematopoietic disorders. However, the yield of CB-HSCs per graft is limited and often insufficient, particularly for the treatment of adult patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87be735e43b2a79a5a90dd9179c7d52d
https://doi.org/10.1002/term.1486
https://doi.org/10.1002/term.1486
Autor:
Frank Staib, Tom Luedde, Anja Hohmeyer, Lars Zender, Gudrun Walenda, Frank Tacke, Tetyana Yevsa, Sergio A. Lira, Mihael Vucur, Carlo Schneider, Hermann E. Wasmuth, Andreas Teufel, Christian Trautwein, Henning W. Zimmermann, Sebastian Huss, Nikolaus Gassler
Publikováno v:
Gut. 61:1733-1743
Background Hepatocellular carcinoma (HCC) is a typical inflammation-associated cancer, but may also provoke antitumour immune responses whose significance and underlying mechanisms are incompletely understood. Objective To characterise immune respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da91baf31bf712a034f7270b61f4400
https://doi.org/10.1136/gutjnl-2011-301116
https://doi.org/10.1136/gutjnl-2011-301116
Autor:
Khalid Abnaof, Kurt Hoffmann, Holger Fröhlich, Nikhil Mallela, Steffen K. Meurer, Martin Zenke, Ralf Weiskirchen, Bert Smeets, Kristin Seré, Wolfgang Wagner, Qiong Lin, Gudrun Walenda
Publikováno v:
BMC systems biology 8, 55 (2014). doi:10.1186/1752-0509-8-55
BMC Systems Biology, 8:55. BioMed Central Ltd
BMC Systems Biology
BMC Systems Biology, 8:55. BioMed Central Ltd
BMC Systems Biology
BMC systems biology 8(1), 55 (2014). doi:10.1186/1752-0509-8-55
Published by BioMed Central, London
Published by BioMed Central, London
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42711268a9006639997330e56ca8d29a
Autor:
Wolf Drescher, Kristina Reck, Wolfgang Wagner, Tobias May, Tim H. Brümmendorf, Martin Zenke, Carmen M. Koch, Gudrun Walenda, Tomo Saric, Sylvia Joussen, Kaifeng Shao, Qiong Lin, Bertram Opalka, Patrick Ziegler
Pluripotent stem cells evade replicative senescence, whereas other primary cells lose their proliferation and differentiation potential after a limited number of cell divisions, and this is accompanied by specific senescence-associated DNA methylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b71fccb638d64c2e7ae6e9ed867d0017
https://www.ncbi.nlm.nih.gov/pubmed/23080539
https://www.ncbi.nlm.nih.gov/pubmed/23080539