Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Gudmundur H, Gudmundsson"'
Autor:
Xinmeng Liao, Yawen Lan, Wentao Wang, Jinjin Zhang, Rui Shao, Zhan Yin, Gudmundur H. Gudmundsson, Peter Bergman, Kangsen Mai, Qinghui Ai, Min Wan
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTAlthough evidence has shown that vitamin D (VD) influences gut homeostasis, limited knowledge is available how VD regulates intestinal immunity against bacterial infection. In the present study, cyp2r1 mutant zebrafish, lacking the capacity t
Externí odkaz:
https://doaj.org/article/1b693eba75194e52aa296d1bb0de5421
Autor:
Iwona T. Myszor, Snaevar Sigurdsson, Alexia Ros Viktorsdottir, Birgitta Agerberth, Eeva-Liisa Eskelinen, Margret Helga Ogmundsdottir, Gudmundur H. Gudmundsson
Publikováno v:
Journal of Innate Immunity, Pp 1-16 (2022)
Aroylated phenylenediamines (APDs) are novel modulators of innate immunity with respect to enhancing the expression of antimicrobial peptides and maintaining epithelial barrier integrity. Here, we present a new study on induction of autophagy in huma
Externí odkaz:
https://doaj.org/article/9b0312b339784470bde7471b75cf1e7d
Autor:
Xinmeng Liao, Yawen Lan, Rui Shao, Jiayu Liu, Shufei Liang, Zhan Yin, Gudmundur H. Gudmundsson, Peter Bergman, Min Wan
Publikováno v:
Journal of Innate Immunity, Pp 1-14 (2021)
Vitamin D (VD) is a major regulator of calcium metabolism in many living organisms. In addition, VD plays a key role in regulating innate and adaptive immunity in vertebrates. Neutrophils constitute an important part of the first line of defense agai
Externí odkaz:
https://doaj.org/article/547819283e9443539c9f2a1edbcebd4e
Autor:
Ari Jon Arason, Jon Petur Joelsson, Bryndis Valdimarsdottir, Snaevar Sigurdsson, Alexander Gudjonsson, Skarphedinn Halldorsson, Freyr Johannsson, Ottar Rolfsson, Fredrik Lehmann, Saevar Ingthorsson, Paulina Cherek, Gudmundur H. Gudmundsson, Fridrik R. Gardarsson, Clive P. Page, Olafur Baldursson, Thorarinn Gudjonsson, Jennifer A. Kricker
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-19 (2019)
Abstract Background Azithromycin (Azm) is a macrolide recognized for its disease-modifying effects and reduction in exacerbation of chronic airway diseases. It is not clear whether the beneficial effects of Azm are due to its anti-microbial activity
Externí odkaz:
https://doaj.org/article/c8da4be92fa246189c8660fe3fd024d1
Autor:
Iwona T. Myszor, Zahida Parveen, Håkan Ottosson, Peter Bergman, Birgitta Agerberth, Roger Strömberg, Gudmundur H. Gudmundsson
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Abstract Aroylated phenylenediamines (APDs) are novel inducers of innate immunity enhancing cathelicidin gene expression in human bronchial epithelial cell lines. Here we present two newly developed APDs and aimed at defining the response and signali
Externí odkaz:
https://doaj.org/article/c34430d9332c4c8481c652a6656d4119
Autor:
Peter Bergman, Rubhana Raqib, Rokeya Sultana Rekha, Birgitta Agerberth, Gudmundur H. Gudmundsson
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The innate immune system constitutes the first line of defense against invading pathogens, regulating the normal microbiota and contributes to homeostasis. Today we have obtained detailed knowledge on receptors, signaling pathways, and effector molec
Externí odkaz:
https://doaj.org/article/c4e2baccab3b4b0ea0dcb73e6073c34e
Autor:
Rokeya Sultana Rekha, Akhirunnesa Mily, Tajnin Sultana, Ahsanul Haq, Sultan Ahmed, S. M. Mostafa Kamal, Annemarie van Schadewijk, Pieter S. Hiemstra, Gudmundur H. Gudmundsson, Birgitta Agerberth, Rubhana Raqib
Publikováno v:
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background We have previously shown that 8 weeks’ treatment with phenylbutyrate (PBA) (500mgx2/day) with or without vitamin D3 (vitD3) (5000 IU/day) as host-directed therapy (HDT) accelerated clinical recovery, sputum culture conversion an
Externí odkaz:
https://doaj.org/article/13ff43c95026410299f75ffb75fa81f2
Autor:
Li-Long Pan, Yuan-Yuan Deng, Ruxing Wang, Chengfei Wu, Jiahong Li, Wenying Niu, Qin Yang, Madhav Bhatia, Gudmundur H. Gudmundsson, Birgitta Agerberth, Julien Diana, Jia Sun
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Acute pancreatitis (AP) is one common clinical acute abdominal disease, for which specific pharmacological or nutritional therapies remain elusive. Lactose, a macronutrient and an inducer of host innate immune responses, possesses immune modulatory f
Externí odkaz:
https://doaj.org/article/276da0c978ae484088e07adc6b23deaa
Autor:
Yawen Lan, Xinmeng Liao, Peter Bergman, Rui Shao, Zhan Yin, Jiayu Liu, Shufei Liang, Gudmundur H. Gudmundsson, Min Wan
Publikováno v:
Journal of Innate Immunity. 14:229-242
Vitamin D (VD) is a major regulator of calcium metabolism in many living organisms. In addition, VD plays a key role in regulating innate and adaptive immunity in vertebrates. Neutrophils constitute an important part of the first line of defense agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b58eaadd3ce9ab63585034cd1de9be9
https://doi.org/10.1159/000519183
https://doi.org/10.1159/000519183
Autor:
Protim Sarker, Akhirunnesa Mily, Abdullah Al Mamun, Shah Jalal, Peter Bergman, Rubhana Raqib, Gudmundur H. Gudmundsson, Birgitta Agerberth
Publikováno v:
Antibiotics, Vol 3, Iss 3, Pp 353-374 (2014)
Antibiotics exert several effects on host cells including regulation of immune components. Antimicrobial peptides (AMPs), e.g., cathelicidins and defensins display multiple functions in innate immunity. In colonic mucosa, cathelicidins are induced by
Externí odkaz:
https://doaj.org/article/219adfcfa308408987771a7adb6addde