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Molecular physiology of absorbtive and secretory functions of amphibian skin

Autor: Larsen, EH, Sørensen, JB, Amstrup, J, Mejlvang, JP, Gudme, CN, Nielsen, MS, Willumsen, NJ, Å, Jespersen, Nielsen, R

Publikováno v: In Comparative Biochemistry and Physiology, Part A 1999 124 Supplement 1:S145-S145

Increased basement membrane turnover and strongly attenuated interstitial matrix turnover is a key pathological feature of haemophilia.

Autor: Manon-Jensen T; Nordic Bioscience A/S, Herlev, Denmark., Hua BL; Department of Haematology, Peking Union Medical College Hospital (PUMCH), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College (PUMC), Beijing, China., Olsen EHN; Novo Nordisk A/S, Maaloev, Denmark., Sun S; Nordic Bioscience A/S, Herlev, Denmark., Gudme CN; Novo Nordisk A/S, Maaloev, Denmark., Li J; Novo Nordisk Research Centre China, Beijing, China., Lei W; Novo Nordisk Research Centre China, Beijing, China., Vandahl B; Novo Nordisk A/S, Maaloev, Denmark., Roepstorff K; Novo Nordisk A/S, Maaloev, Denmark., Kjelgaard-Hansen M; Novo Nordisk A/S, Maaloev, Denmark., Zhao Y; Department of Haematology, Peking Union Medical College Hospital (PUMCH), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College (PUMC), Beijing, China., Karsdal MA; Nordic Bioscience A/S, Herlev, Denmark.

Publikováno v: Haemophilia : the official journal of the World Federation of Hemophilia [Haemophilia] 2017 Nov; Vol. 23 (6), pp. e515-e518. Date of Electronic Publication: 2017 Aug 29.

Post hoc assessment of the immunogenicity of bioengineered factor VIIa demonstrates the use of preclinical tools.

Autor: Lamberth K; Global Research, Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Måløv, Denmark. zuben.sauna@fda.hhs.gov kplm@novonordisk.com., Reedtz-Runge SL; Global Research, Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Måløv, Denmark., Simon J; Hemostasis Branch, Division of Plasma Protein Therapeutics, Office of Tissues and Advanced Therapeutics, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA., Klementyeva K; Hemostasis Branch, Division of Plasma Protein Therapeutics, Office of Tissues and Advanced Therapeutics, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA., Pandey GS; Hemostasis Branch, Division of Plasma Protein Therapeutics, Office of Tissues and Advanced Therapeutics, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA., Padkjær SB; Global Research, Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Måløv, Denmark., Pascal V; Global Research, Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Måløv, Denmark., León IR; Global Research, Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Måløv, Denmark., Gudme CN; Global Research, Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Måløv, Denmark., Buus S; Laboratory of Experimental Immunology, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark., Sauna ZE; Hemostasis Branch, Division of Plasma Protein Therapeutics, Office of Tissues and Advanced Therapeutics, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA. zuben.sauna@fda.hhs.gov kplm@novonordisk.com.

Publikováno v: Science translational medicine [Sci Transl Med] 2017 Jan 11; Vol. 9 (372).

A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models.

Autor: Stennicke HR; Novo Nordisk, Måløv, Denmark. hrse@novonordisk.com, Kjalke M, Karpf DM, Balling KW, Johansen PB, Elm T, Øvlisen K, Möller F, Holmberg HL, Gudme CN, Persson E, Hilden I, Pelzer H, Rahbek-Nielsen H, Jespersgaard C, Bogsnes A, Pedersen AA, Kristensen AK, Peschke B, Kappers W, Rode F, Thim L, Tranholm M, Ezban M, Olsen EH, Bjørn SE

Publikováno v: Blood [Blood] 2013 Mar 14; Vol. 121 (11), pp. 2108-16. Date of Electronic Publication: 2013 Jan 18.