Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Gudan Xu"'
Autor:
Liyuan Kong, Gudan Xu, Xiaoqin Liu, Jingwen Wang, Zenglin Tang, You-Sheng Cai, Kun Shen, Weixin Tao, Yu Zheng, Zixin Deng, Neil P.J. Price, Wenqing Chen
Publikováno v:
iScience, Vol 22, Iss , Pp 430-440 (2019)
Summary: Minimycin (MIN) is a C-nucleoside antibiotic structurally related to pseudouridine, and indigoidine is a naturally occurring blue pigment produced by diverse bacteria. Although MIN and indigoidine have been known for decades, the logic under
Externí odkaz:
https://doaj.org/article/464197e4a7954be3b7f3ed4145ef57cf
Autor:
Weixin Tao, Neil P. J. Price, Liyuan Kong, Xiaoqin Liu, Kun Shen, Tang Zenglin, Gudan Xu, Yu Zheng, You-Sheng Cai, Zixin Deng, Wenqing Chen, Jingwen Wang
Publikováno v:
iScience, Vol 22, Iss, Pp 430-440 (2019)
iScience
iScience
Summary Minimycin (MIN) is a C-nucleoside antibiotic structurally related to pseudouridine, and indigoidine is a naturally occurring blue pigment produced by diverse bacteria. Although MIN and indigoidine have been known for decades, the logic underl
Autor:
Pan Wu, Xiaoxia Chen, Jianzhao Qi, Wenqing Chen, Jian Zhu, Yaojie Gao, Gui Wang, Yong-Quan Li, Gudan Xu, Hongmin Ma, Zixin Deng, Tingting Wang, Dan Wan
Publikováno v:
Cell Chemical Biology. 24:171-181
Summary Pentostatin (PTN, deoxycoformycin) and arabinofuranosyladenine (Ara-A, vidarabine) are purine nucleoside antibiotics used clinically to treat hematological cancers and human DNA virus infections, respectively. PTN has a 1,3-diazepine ring, an
Autor:
Xiaochen Zhu, Yongxing Lei, Zixin Deng, Yaojie Gao, Baofu Xu, Wenqing Chen, Nisha He, Youli Xiao, Jianzhao Qi, Pan Wu, Gudan Xu, Gong-Li Tang
Publikováno v:
Chemical Science. 8:444-451
Unique bicyclic octosyl uronic acid nucleosides include ezomycin, malayamycin, and octosyl acid (OA). They are structurally characterized by OA, an unusual 8-carbon furanosyl nucleoside core proposed to be the precursor to polyoxin and nikkomycin. De
Autor:
Meng Zhang, Wenting Zhou, Peichao Zhang, Rong Gong, Gudan Xu, Yaojie Gao, Neil P. J. Price, You-Sheng Cai, Wenqing Chen, Hengjiang Cong, Zixin Deng, Xiangzhao Mao
Publikováno v:
Appl Environ Microbiol
Formycin A (FOR-A) and pyrazofurin A (PRF-A) are purine-relatedC-nucleoside antibiotics, in which ribose and a pyrazole-derived base are linked by aC-glycosidic bond, however, the logic underlying the biosynthesis of these molecules has remained larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a45658615db49feee295b452797286
https://doi.org/10.1101/728154
https://doi.org/10.1101/728154
Autor:
Rong Gong, Gudan Xu, Yaojie Gao, Zixin Deng, Ming Jiang, Liyuan Kong, Neil P. J. Price, Liudong Xu, Kui Hong, Youcai Hu, You-Sheng Cai, Wenqing Chen, Peng Liu
Publikováno v:
Applied and Environmental Microbiology. 84
Purine nucleoside antibiotic pairs, concomitantly produced by a single strain, are an important group of microbial natural products. Here, we report a target-directed genome mining approach to elucidate the biosynthesis of the purine nucleoside antib
Publikováno v:
Applied and Environmental Microbiology. 83
2′-Chloropentostatin (2′-Cl PTN, 2′-chloro-2′-deoxycoformycin) and 2′-amino-2′-deoxyadenosine (2′-amino dA) are two adenosine-derived nucleoside antibiotics coproduced by Actinomadura sp. strain ATCC 39365. 2′-Cl PTN is a potent adeno
Publikováno v:
Applied and environmental microbiology. 83(10)
2′-Chloropentostatin (2′-Cl PTN, 2′-chloro-2′-deoxycoformycin) and 2′-amino-2′-deoxyadenosine (2′-amino dA) are two adenosine-derived nucleoside antibiotics coproduced by Actinomadura sp. strain ATCC 39365. 2′-Cl PTN is a potent adeno
Autor:
Nisha, He, Pan, Wu, Yongxing, Lei, Baofu, Xu, Xiaochen, Zhu, Gudan, Xu, Yaojie, Gao, Jianzhao, Qi, Zixin, Deng, Gongli, Tang, Wenqing, Chen, Youli, Xiao
Publikováno v:
Chemical Science
This work provides, for the first time, significant in vitro evidence for the biosynthetic origins of octosyl acid through free radical and dephosphorylation enzymatic reactions.
Unique bicyclic octosyl uronic acid nucleosides include ezomycin,
Unique bicyclic octosyl uronic acid nucleosides include ezomycin,
Autor:
Gudan Xu1, Liyuan Kong1,2, Rong Gong1, Liudong Xu3, Yaojie Gao3, Ming Jiang3, You-Sheng Cai1, Kui Hong1, Youcai Hu2, Peng Liu1, Zixin Deng1,3, Price, Neil P. J.4, Wenqing Chen1,2,3 wqchen@whu.edu.cn
Publikováno v:
Applied & Environmental Microbiology. Nov2018, Vol. 84 Issue 22, p1-16. 16p.