Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Guck T. Ooi"'
Publikováno v:
Molecular and Cellular Endocrinology. 436:68-77
This study tested the hypothesis that inhibins act in an autocrine manner on Leydig cells using a pre-pubertal Leydig cell line, TM3, as a model of immature Leydig cells. The expression of Inha, Inhba, and Inhbb in TM3 cells was determined by RT-PCR
Autor:
Yoko Murata, Rosario Dominguez Crespo Hirata, Lidio Gonçalves Lima Neto, Dikran Armaganijan, Marcos Paulo Pereira, Earl W. Ferguson, Sun H. Paik, Elizabete Silva dos Santos, Rui F. Ramos, Marcelo Ferraz Sampaio, Carla Prisinzano Pastorelli, Mario Hiroyuki Hirata, André Ducati Luchessi, Vivian Nogueira Silbiger, Guck T. Ooi, Eric K.M. Ueda
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
BackgroundThe aim of this study was to identify novel candidate biomarker proteins differentially expressed in the plasma of patients with early stage acute myocardial infarction (AMI) using SELDI-TOF-MS as a high throughput screening technology.Meth
Publikováno v:
Molecular and Cellular Endocrinology. 307:149-156
Betaglycan is an inhibin-binding protein co-receptor, the forced expression of which confers inhibin responsiveness on cells previously non-responsive to inhibin. The present study determines whether removal of betaglycan expression in otherwise inhi
Publikováno v:
Human Reproduction. 22:3241-3248
A nucleotide substitution in the inhibin alpha subunit (INHA 769GA, A257T) has been associated with premature ovarian failure (POF). We hypothesize this mutation causes a reduction in inhibin bioactivity, removing its suppression on the pituitary FSH
Autor:
Ruth Escalona, Guck T. Ooi, Gregory E. Rice, Nicole L. Dellios, I. Ross Young, Helena C. Parkington, Jonathan J. Hirst, Hannah K. Palliser
Publikováno v:
Biology of Reproduction. 72:937-943
Prostaglandins (PGs) play a pivotal role in the initiation and progression of term and preterm labor. Uterine activity is stimulated primarily by PGE(2) and PGF(2alpha) acting on prostaglandin E (EP) and prostaglandin F (FP) receptors, respectively.
Autor:
Nicole L. Dellios, Ruth Escalona, Hannah K. Palliser, Gregory E. Rice, Guck T. Ooi, Jonathan J. Hirst, IR Young
Publikováno v:
Journal of Endocrinology. 180:469-477
The differential production of prostaglandin (PG) F(2 alpha) and PGE(2) within the uterine compartment may play a role in controlling myometrial contraction. We hypothesized that the enzymes downstream of PG endoperoxide synthase-2 (PGHS-2) determine
Autor:
Guiying Nie, Ying Li, Hiroyuki Minoura, Jock K. Findlay, Lois A. Salamonsen, Leigh Batten, Guck T. Ooi
Publikováno v:
Molecular Human Reproduction. 9:279-290
This paper characterizes a novel gene, previously identified as uniquely regulated at implantation in mouse uterus. We cloned its full mRNA sequence encoding a serine protease possessing an IGF-binding domain and named it pregnancy-related serine pro
Autor:
Liza O'Donnell, Peter G. Stanton, Guck T. Ooi, Robert I McLachlan, David Robertson, Kyriakos Pratis
Publikováno v:
Journal of Endocrinology. 176:393-403
Testosterone is metabolised to the more potent androgen, dihydrotestosterone, by the 5alpha-reductase (5alphaR) enzyme. We previously showed that 5alpha-reduced androgens are important for maintaining androgen action on rat spermatogenesis when testi
Publikováno v:
Molecular Endocrinology. 16:2754-2763
Activin stimulates expression of GnRH receptor (GnRHR) and FSH beta-subunit in gonadotropes. Inhibin antagonizes activin actions on the gonadotropes, but its molecular mechanism of action remains poorly understood. It has been suggested that inhibin
Autor:
Shoshana Yakar, Clifford J. Rosen, Wesley G. Beamer, Cheryl L. Ackert-Bicknell, Yiping Wu, Jun-Li Liu, Guck T. Ooi, Jennifer Setser, Jan Frystyk, Yves R. Boisclair, Derek LeRoith
Publikováno v:
Journal of Clinical Investigation. 110:771-781