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Autor:
Narvaez, AJ, Ber, S, Crooks, A, Emery, A, Hardwick, B, Guarino Almeida, E, Huggins, DJ, Perera, D, Roberts-Thomson, M, Azzarelli, R, Hood, FE, Prior, IA, Walker, DW, Boyce, R, Boyle, RG, Barker, SP, Torrance, CJ, McKenzie, GJ, Venkitaraman, AR
Mutations activating KRAS underlie many forms of cancer, but are refractory to therapeutic targeting. Here, we develop Poloppin, an inhibitor of protein-protein interactions via the Polo-box domain (PBD) of the mitotic Polo-like kinases (PLKs), in mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::beb31fa33546d5692971bfee36b6f8e2
Autor:
Guarino Almeida E; The Medical Research Council Cancer Unit, University of Cambridge, Hills Road, Cambridge CB2 0XZ, UK., Renaudin X; The Medical Research Council Cancer Unit, University of Cambridge, Hills Road, Cambridge CB2 0XZ, UK., Venkitaraman AR; The Medical Research Council Cancer Unit, University of Cambridge, Hills Road, Cambridge CB2 0XZ, UK.
Publikováno v:
Nucleic acids research [Nucleic Acids Res] 2020 Aug 20; Vol. 48 (14), pp. 7844-7855.
Autor:
Palles C; Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Cazier JB, Howarth KM, Domingo E, Jones AM, Broderick P, Kemp Z, Spain SL, Guarino E, Salguero I, Sherborne A, Chubb D, Carvajal-Carmona LG, Ma Y, Kaur K, Dobbins S, Barclay E, Gorman M, Martin L, Kovac MB, Humphray S, Lucassen A, Holmes CC, Bentley D, Donnelly P, Taylor J, Petridis C, Roylance R, Sawyer EJ, Kerr DJ, Clark S, Grimes J, Kearsey SE, Thomas HJ, McVean G, Houlston RS, Tomlinson I
Publikováno v:
Nature genetics [Nat Genet] 2013 Feb; Vol. 45 (2), pp. 136-44. Date of Electronic Publication: 2012 Dec 23.