SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis.

Autor: Breunig K, Lei X, Montalbano M, Guardia GDA, Ostadrahimi S, Alers V, Kosti A, Chiou J, Klein N, Vinarov C, Wang L, Li M, Song W, Kraus WL, Libich DS, Tiziani S, Weintraub ST, Galante PAF, Penalva LOF

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 12. Date of Electronic Publication: 2024 Oct 12.

Identification of a novel alternative splicing isoform of the Hippo kinase STK3/MST2 with impaired kinase and cell growth suppressing activities.

Autor: Rodrigues AM; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil., Paula Zen Petisco Fiore A; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.; Department of Biology, New York University, New York, NY, USA., Guardia GDA; Centro de Oncologia Molecular, Hospital Sírio-Libanês, São Paulo, Brazil., Tomasin R; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil., Azevedo Reis Teixeira A; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil., Giordano RJ; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil., Schechtman D; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil., Pagano M; Department of Biochemistry and Molecular Pharmacology, Howard Hughes Medical Institute, New York University Grossman School of Medicine, New York, NY, USA., Galante PAF; Centro de Oncologia Molecular, Hospital Sírio-Libanês, São Paulo, Brazil., Bruni-Cardoso A; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil. brunicar@iq.usp.

Publikováno v: Oncogene [Oncogene] 2024 Sep; Vol. 43 (39), pp. 2938-2950. Date of Electronic Publication: 2024 Aug 22.

Impact of the thyroid hormone T3 and its nuclear receptor TRα1 on colon cancer stem cell phenotypes and response to chemotherapies.

Autor: Giolito MV; Université de Strasbourg, INSERM, IRFAC/UMR-S1113, FMTS, 67200, Strasbourg, France.; Pole of Pharmacology and Therapeutics (FATH), Institut de Recherche Experimentale et Clinique (IREC), UCLouvain, Avenue Hippocrate 57, B1.57.04, B-1200, Brussels, Belgium., Bodoirat S; Université de Strasbourg, INSERM, IRFAC/UMR-S1113, FMTS, 67200, Strasbourg, France., La Rosa T; Stem-Cell and Brain Research Institute, U1208 INSERM, USC1361 INRA, 69675, Bron, France., Reslinger M; Université de Strasbourg, INSERM, IRFAC/UMR-S1113, FMTS, 67200, Strasbourg, France.; Université de Strasbourg, CNRS, INSERM, IGBMC UMR 7104-UMR-S 1258, Illkirch, France., Guardia GDA; Centro de Oncologia Molecular, Hospital Sírio-Libanês, São Paulo, Brazil., Mourtada J; Université de Strasbourg, INSERM, IRFAC/UMR-S1113, FMTS, 67200, Strasbourg, France., Claret L; Université de Strasbourg, INSERM, IRFAC/UMR-S1113, FMTS, 67200, Strasbourg, France.; Université de Strasbourg, CNRS, INSERM, IGBMC UMR 7104-UMR-S 1258, Illkirch, France., Joung A; Université de Strasbourg, INSERM, IRFAC/UMR-S1113, FMTS, 67200, Strasbourg, France.; Laboratoire de Biologie Tumorale, Institut de Cancérologie Strasbourg Europe, Strasbourg, France., Galante PAF; Centro de Oncologia Molecular, Hospital Sírio-Libanês, São Paulo, Brazil., Penalva LOF; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Plateroti M; Université de Strasbourg, INSERM, IRFAC/UMR-S1113, FMTS, 67200, Strasbourg, France. michelina.plateroti@igbmc.fr.; Université de Strasbourg, CNRS, INSERM, IGBMC UMR 7104-UMR-S 1258, Illkirch, France. michelina.plateroti@igbmc.fr.

Publikováno v: Cell death & disease [Cell Death Dis] 2024 May 01; Vol. 15 (5), pp. 306. Date of Electronic Publication: 2024 May 01.

Tissue-resident glial cells associate with tumoral vasculature and promote cancer progression.

Autor: Rocha BGS; Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Picoli CC; Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Gonçalves BOP; Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Silva WN; Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Costa AC; Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Moraes MM; Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Costa PAC; Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Santos GSP; Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Almeida MR; Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Silva LM; Department of Cell Biology, Ezequiel Dias Foundation, Belo Horizonte, MG, Brazil., Singh Y; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Falchetti M; Department of Microbiology and Immunology, Federal University of Santa Catarina, Florianópolis, Brazil., Guardia GDA; Centro de Oncologia Molecular, Hospital Sirio-Libanes, Sao Paulo, SP, Brazil., Guimarães PPG; Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Russo RC; Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Resende RR; Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Pinto MCX; Institute of Biological Sciences, Federal University of Goiás, Goiânia, GO, Brazil., Amorim JH; Center of Biological Sciences and Health, Federal University of Western Bahia, Barreiras, BA, Brazil., Azevedo VAC; Department of Genetics, Ecology and Evolution, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Kanashiro A; Department of Dermatology, University of Wisconsin-Madison, Medical Sciences Center, Rm 4385, 1300 University Avenue, Madison, WI, 53706, USA., Nakaya HI; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Rocha EL; Department of Microbiology and Immunology, Federal University of Santa Catarina, Florianópolis, Brazil., Galante PAF; Centro de Oncologia Molecular, Hospital Sirio-Libanes, Sao Paulo, SP, Brazil., Mintz A; Department of Radiology, Columbia University Medical Center, New York, NY, USA., Frenette PS; Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York, NY, USA.; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY, USA.; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA., Birbrair A; Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. birbrair@wisc.edu.; Department of Dermatology, University of Wisconsin-Madison, Medical Sciences Center, Rm 4385, 1300 University Avenue, Madison, WI, 53706, USA. birbrair@wisc.edu.; Department of Radiology, Columbia University Medical Center, New York, NY, USA. birbrair@wisc.edu.

Publikováno v: Angiogenesis [Angiogenesis] 2023 Feb; Vol. 26 (1), pp. 129-166. Date of Electronic Publication: 2022 Oct 01.

ELF4 is a critical component of a miRNA-transcription factor network and is a bridge regulator of glioblastoma receptor signaling and lipid dynamics.

Autor: Kosti A; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas,USA.; Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA., Chiou J; Department of Nutritional Sciences, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, Austin, Texas, USA., Guardia GDA; Centro de Oncologia Molecular, Hospital Sirio-Libanes, São Paulo, Brazil., Lei X; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas,USA.; Department of Nutritional Sciences, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, Austin, Texas, USA., Balinda H; Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas,USA., Landry T; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas,USA., Lu X; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas,USA.; Department of Nutritional Sciences, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, Austin, Texas, USA., Qiao M; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas,USA., Gilbert A; Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA., Brenner A; Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas,USA., Galante PAF; Centro de Oncologia Molecular, Hospital Sirio-Libanes, São Paulo, Brazil.; Departamento de Bioquimica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil., Tiziani S; Department of Nutritional Sciences, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, Austin, Texas, USA., Penalva LOF; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas,USA.; Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.

Publikováno v: Neuro-oncology [Neuro Oncol] 2023 Mar 14; Vol. 25 (3), pp. 459-470.