Multiomic Analysis Reveals Disruption of Cholesterol Homeostasis by Cannabidiol in Human Cell Lines.

Autor: Guard SE; Department of Molecular, Cellular & Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA., Chapnick DA; Department of Biochemistry, University of Colorado Boulder, Boulder, Colorado, USA., Poss ZC; Department of Molecular, Cellular & Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA., Ebmeier CC; Department of Molecular, Cellular & Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA., Jacobsen J; Department of Molecular, Cellular & Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA., Nemkov T; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, Colorado, USA., Ball KA; Department of Molecular, Cellular & Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA., Webb KJ; Department of Molecular, Cellular & Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA., Simpson HL; Department of Molecular, Cellular & Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA., Coleman S; Department of Molecular, Cellular & Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA., Bunker E; Department of Biochemistry, University of Colorado Boulder, Boulder, Colorado, USA., Ramirez A; Department of Biochemistry, University of Colorado Boulder, Boulder, Colorado, USA., Reisz JA; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, Colorado, USA., Sievers R; Department of Chemistry and Cooperative Institute for Research in Environmental Sciences, University of Colorado Boulder, Boulder, Colorado, USA., Stowell MHB; Department of Molecular, Cellular & Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA., D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, Colorado, USA., Liu X; Department of Biochemistry, University of Colorado Boulder, Boulder, Colorado, USA., Old WM; Department of Molecular, Cellular & Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA. Electronic address: william.old@colorado.edu.

Publikováno v: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2022 Oct; Vol. 21 (10), pp. 100262. Date of Electronic Publication: 2022 Jun 24.

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.

Autor: Guard SE; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, USA., Poss ZC; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, USA., Ebmeier CC; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, USA., Pagratis M; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, USA., Simpson H; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, USA., Taatjes DJ; Department of Biochemistry, University of Colorado, Boulder, CO, USA., Old WM; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, USA. William.Old@colorado.edu.; Linda Crnic Institute for Down Syndrome, University of Colorado School of Medicine, Aurora, CO, USA. William.Old@colorado.edu.

Publikováno v: Scientific reports [Sci Rep] 2019 Apr 25; Vol. 9 (1), pp. 6539. Date of Electronic Publication: 2019 Apr 25.