Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Guanzhang Li"'
Autor:
Min Wu, Tingting Wang, Nan Ji, Ting Lu, Ran Yuan, Lingxiang Wu, Junxia Zhang, Mengyuan Li, Penghui Cao, Jiarui Zhao, Guanzhang Li, Jianyu Li, Yu Li, Yujie Tang, Zhengliang Gao, Xiuxing Wang, Wen Cheng, Ming Ge, Gang Cui, Rui Li, Anhua Wu, Yongping You, Wei Zhang, Qianghu Wang, Jian Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Glioblastoma (GBM) is the most common brain tumor and remains incurable. Primary GBM cultures are widely used tools for drug screening, but there is a lack of genomic and pharmacological characterization for these primary GBM cultures. Here,
Externí odkaz:
https://doaj.org/article/7bb838305ea74eeda6edfce6d4224acf
Autor:
Xiaoteng Cui, Jixing Zhao, Guanzhang Li, Chao Yang, Shixue Yang, Qi Zhan, Junhu Zhou, Yunfei Wang, Menglin Xiao, Biao Hong, Kaikai Yi, Fei Tong, Yanli Tan, Hu Wang, Qixue Wang, Tao Jiang, Chuan Fang, Chunsheng Kang
Publikováno v:
Cancer Communications, Vol 43, Iss 12, Pp 1326-1353 (2023)
Abstract Background Metabolism reprogramming plays a vital role in glioblastoma (GBM) progression and recurrence by producing enough energy for highly proliferating tumor cells. In addition, metabolic reprogramming is crucial for tumor growth and imm
Externí odkaz:
https://doaj.org/article/00cb3e09a93e47169bf92b48fab6f99a
Autor:
You Zhai, Yicong Du, Guanzhang Li, Mingchen Yu, Huimin Hu, Changqing Pan, Di Wang, Zhongfang Shi, Xu Yan, Xuesong Li, Tao Jiang, Wei Zhang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract Chimeric antigen receptor (CAR) T-cell therapy has demonstrated clinical response in treating both hematologic malignancies and solid tumors. Although instances of rapid tumor remissions have been observed in animal models and clinical trial
Externí odkaz:
https://doaj.org/article/6e9d1092f49a44b8a0598fb35f2b5bf1
Autor:
Yanfei Wei, Guanzhang Li, Jing Feng, Fan Wu, Zheng Zhao, Zhaoshi Bao, Wei Zhang, Xiaodong Su, Jiuyi Li, Xueling Qi, Zejun Duan, Yunqiu Zhang, Sandra Ferreyra Vega, Asgeir Store Jakola, Yingyu Sun, Helena Carén, Tao Jiang, Xiaolong Fan
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-19 (2023)
Abstract Background Roughly 50% of adult gliomas harbor isocitrate dehydrogenase (IDH) mutations. According to the 2021 WHO classification guideline, these gliomas are diagnosed as astrocytomas, harboring no 1p19q co-deletion, or oligodendrogliomas,
Externí odkaz:
https://doaj.org/article/e0de94ca76e2461c84fa07fbcceeb6fd
Autor:
Chen Wang, Di Wang, Changqing Pan, Jiazheng Zhang, Cheng Cheng, You Zhai, Mingchen Yu, Zhiliang Wang, Guanzhang Li, Wei Zhang
Publikováno v:
Chinese Neurosurgical Journal, Vol 8, Iss 1, Pp 1-6 (2022)
Abstract Background Diagnosis and treatment of patients with glioblastoma (GBM) who are also diagnosed with primary non-central nervous system (CNS) tumors remain a challenge, yet little is known about the clinical characteristics and prognosis of th
Externí odkaz:
https://doaj.org/article/66c6504ed34c4cca9858a7172428214f
Autor:
Zheng Zhao, Ke-Nan Zhang, Zhiyan Sun, Changlin Yang, Qiangwei Wang, Guanzhang Li, Zhiliang Wang, Fan Zeng, Ruichao Chai, Zenghui Qian, Zheng Wang, Yanwei Liu, Wenping Ma, Fan Wu, Tao Jiang
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-8 (2022)
Measurement(s) glioma Technology Type(s) Whole Exome Sequencing Sample Characteristic - Organism Homo sapiens
Externí odkaz:
https://doaj.org/article/8a64322bea98490594ae1f6ca30d8eb0
Autor:
Kenan Zhang, Xing Liu, Guanzhang Li, Xin Chang, Shouwei Li, Jing Chen, Zheng Zhao, Jiguang Wang, Tao Jiang, Ruichao Chai
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 10, Pp 1460-1476 (2022)
Objective: We aimed to summarize the clinicopathological characteristics and prognostic features of various molecular subtypes of diffuse gliomas (DGs) in the Chinese population. Methods: In total, 1,418 patients diagnosed with DG between 2011 and 20
Externí odkaz:
https://doaj.org/article/03908d260a134c6f8e42b2d3ecce6698
Autor:
Yanwei Liu, Huiyuan Chen, Guanzhang Li, Jing Zhang, Kun Yao, Chenxing Wu, Shouwei Li, Xiaoguang Qiu
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 10, Pp 1477-1486 (2022)
Objective: IDH-mutant lower-grade gliomas (LGGs, grade 2 or 3) eventually transform into secondary grade 4 astrocytomas (sAIDHmut/G4). Here, we sought to describe the transformation time, risk factors, and outcomes in malignant transformation of IDH-
Externí odkaz:
https://doaj.org/article/da7ca752161c4d66915622d91f1cb1b5
Autor:
Zhiliang Wang, Wen Cheng, Zheng Zhao, Zheng Wang, Chuanbao Zhang, Guanzhang Li, Anhua Wu, Tao Jiang
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 4, Pp 533-550 (2022)
Objective: Lower grade gliomas (LGGs), classified as World Health Organization (WHO) grade II and grade III gliomas, comprise a heterogeneous group with a median survival time ranging from 4–13 years. Accurate prediction of the survival times of LG
Externí odkaz:
https://doaj.org/article/507db5bcd1a94a7e9a65971b94d85e4b
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Triggering receptor expressed on myeloid cells 2 (TREM2) is expressed in myeloid cells of the central nervous system (CNS), which mediate the immunological response in a variety of diseases. Uncertain is the function of TREM2 in glioma and tumor immu
Externí odkaz:
https://doaj.org/article/ac7e30e8a7d74329a2db9062b61ffd77