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Interleukin-32α inactivates JAK2/STAT3 signaling and reverses interleukin-6-induced epithelial–mesenchymal transition, invasion, and metastasis in pancreatic cancer cells

Autor: Mengtao Zhou, Heyi You, Zongjing Chen, Bicheng Chen, Hongwei Sun, Jiadong Su, Silu Wang, Jingfeng Chen, Guanyu Chu

Publikováno v: OncoTargets and therapy

Jingfeng Chen,1,2,* Silu Wang,1,* Jiadong Su,1 Guanyu Chu,1 Heyi You,1 Zongjing Chen,1 Hongwei Sun,1 Bicheng Chen,1,3 Mengtao Zhou1 1Department of Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 2Department of Surgery,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae23307a837e4cd75ccb603fbd84106c
https://doi.org/10.2147/ott.s103581

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Luteolin inhibits angiogenesis of the M2‑like TAMs via the downregulation of hypoxia inducible factor‑1α and the STAT3 signalling pathway under hypoxia

Autor: Chunwu Zhang, Zhenxu Zhou, Bicheng Chen, Hongru Kong, Xuehai Chen, Binbo Fang, Minmin Wu, Guanyu Chu

Publikováno v: Molecular medicine reports. 18(3)

The imbalance between angiogenic inducers and inhibitors appears to be a critical factor in tumour pathogenesis. Angiogenesis serves a key role in the occurrence, invasion and metastasis of tumours. Macrophages are a major cellular component of human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c71a27cffcdfac19e2763992abc1fd8
https://pubmed.ncbi.nlm.nih.gov/30015852

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