Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Guanylyltransferase activity"'
Publikováno v:
Molecular Plant Pathology
Rice black‐streaked dwarf virus (RBSDV) (species Rice black‐streaked dwarf virus, genus Fijivirus, family Reoviridae) is the causal agent of rice black‐streaked dwarf and maize rough dwarf diseases, which occur in intermittent epidemics in East
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8855ac377f4db88f9dc1642a317be1
https://doi.org/10.1111/mpp.12946
https://doi.org/10.1111/mpp.12946
SARS-CoV-2 is a positive-sense RNA virus that is responsible for the ongoing Coronavirus Disease 2019 (COVID-19) pandemic, which continues to cause significant morbidity, mortality and economic strain. SARS-CoV-2 can cause severe respiratory disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9fd256e9e7a993701917e6343d02592
https://doi.org/10.1101/2021.03.17.435913
https://doi.org/10.1101/2021.03.17.435913
Autor:
Ashanti O. Matlock, Jane E. Jackman, Avraham Shaag, Katherine Labbé, Krishna J. Patel, Chaim Jalas, Yael Elbaz-Alon, Orly Elpeleg, Simon Edvardson
Publikováno v:
neurogenetics. 17:219-225
Autosomal-recessive cerebellar atrophy is usually associated with inactivating mutations and early-onset presentation. The underlying molecular diagnosis suggests the involvement of neuronal survival pathways, but many mechanisms are still lacking an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9605ea0d1f73f6191897c190e442cc89
https://doi.org/10.1007/s10048-016-0487-z
https://doi.org/10.1007/s10048-016-0487-z
Autor:
Yan Gao, Liming Yan, Tao Wang, Luke W. Guddat, Haofeng Wang, Zhiyong Lou, Yingjian Li, Quan Wang, Zhenyu Liu, Ying Zhang, Litao Zheng, Zihe Rao, Yucen Huang, Yunxiang Yang, Mingyu Li, Shan Gao, Yu Chen, Ji Ge
Publikováno v:
Cell
Transcription of SARS-CoV-2 mRNA requires sequential reactions facilitated by the replication and transcription complex (RTC). Here, we present a structural snapshot of SARS-CoV-2 RTC as it transitions toward cap structure synthesis. We determine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee89e55318224d34db3ffbe67f60fa68
https://doi.org/10.1016/j.cell.2020.11.016
https://doi.org/10.1016/j.cell.2020.11.016
Autor:
Tao Qiu, Cindy L. Luongo
Publikováno v:
Virology. 316(2):313-324
Grass carp reovirus, a segmented double-stranded RNA virus, is a member of the genus aquareovirus in the Reoviridae family. Grass carp reovirus VP1 was shown to be an mRNA guanylyltransferase. The enzyme demonstrated maximum activityor= pH 6.0. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f69d6d77fc0e6a0eb30db17709e7089
Autor:
Nicholas J. Mullen, David H. Price
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186423 (2017)
PLoS ONE
PLoS ONE
Capping of nascent RNA polymerase II (Pol II) transcripts is required for gene expression and the first two steps are catalyzed by separate 5' triphosphatase and guanylyltransferase activities of the human capping enzyme (HCE). The cap is added co-tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab824e16f1334063779866f6207ef24
http://europepmc.org/articles/PMC5640233?pdf=render
http://europepmc.org/articles/PMC5640233?pdf=render
Autor:
Bejan Saeedi, Susan M. Keenan, Amanda M. Hannah, Brian J. Geiss, Hillary J. Stahla-Beek, Daniel G. April
Publikováno v:
Journal of Virology. 86:8730-8739
Arthropod-borne flavivirus infection causes serious morbidity and mortality worldwide, but there are currently no effective antiflaviviral chemotherapeutics available for human use. Therefore, it is critical that new therapeutics against virus-specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c53e65e8d666f7c58accffbb2e334f
https://doi.org/10.1128/jvi.00384-12
https://doi.org/10.1128/jvi.00384-12
Publikováno v:
FEBS Letters. 586:2326-2331
The alphavirus-like mRNA capping enzyme of Bamboo mosaic virus (BaMV) exhibits an AdoMet-dependent guanylyltransferase activity by which the methyl group of AdoMet is transferred to GTP, leading to the formation of m(7)GTP, and the m(7)GMP moiety is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cafde5e65f9c53fd07057bfc26219c87
https://doi.org/10.1016/j.febslet.2012.05.024
https://doi.org/10.1016/j.febslet.2012.05.024
Autor:
Philippe Giegé, Laurence Maréchal-Drouard, Antonio Placido, Anthony Gobert, François Sieber, Raffaele Gallerani
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2010, pp.7711-7717
Nucleic acids research 38 (2010): 7711–7717. doi:10.1093/nar/gkq646
info:cnr-pdr/source/autori:Placido, Antonio; Sieber, Francois; Gobert, Anthony; Gallerani, Raffaele; Giege, Philippe; Marechal-Drouard, Laurence/titolo:Plant mitochondria use two pathways for the biogenesis of tRNA(His)/doi:10.1093%2Fnar%2Fgkq646/rivista:Nucleic acids research/anno:2010/pagina_da:7711/pagina_a:7717/intervallo_pagine:7711–7717/volume:38
Nucleic Acids Research, Oxford University Press, 2010, pp.7711-7717
Nucleic acids research 38 (2010): 7711–7717. doi:10.1093/nar/gkq646
info:cnr-pdr/source/autori:Placido, Antonio; Sieber, Francois; Gobert, Anthony; Gallerani, Raffaele; Giege, Philippe; Marechal-Drouard, Laurence/titolo:Plant mitochondria use two pathways for the biogenesis of tRNA(His)/doi:10.1093%2Fnar%2Fgkq646/rivista:Nucleic acids research/anno:2010/pagina_da:7711/pagina_a:7717/intervallo_pagine:7711–7717/volume:38
All tRNA(His) possess an essential extra G(-1) guanosine residue at their 5' end. In eukaryotes after standard processing by RNase P, G(-1) is added by a tRNA(His) guanylyl transferase. In prokaryotes, G(-1) is genome-encoded and retained during matu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c801374e9c52ed4b03fc6c52ac0af4
https://doi.org/10.1093/nar/gkq646
https://doi.org/10.1093/nar/gkq646
Publikováno v:
Biochemistry. 47:3863-3874
An RNA guanylyltransferase activity is involved in the synthesis of the cap structure found at the 5' end of eukaryotic mRNAs. The RNA guanylyltransferase activity is a two-step ping-pong reaction in which the enzyme first reacts with GTP to produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88356ea99a9a4fec3047275c29edc5c2
https://doi.org/10.1021/bi702054a
https://doi.org/10.1021/bi702054a