The Role of RASGRP2 in Vascular Endothelial Cells—A Mini Review

Autor: Kentaro Nagamine, Shouhei Miyazaki, Jun-ichi Takino, Takamitsu Hori

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 11129, p 11129 (2021)

RAS guanyl nucleotide-releasing proteins (RASGRPs) are important proteins that act as guanine nucleotide exchange factors, which activate small GTPases and function as molecular switches for intracellular signals. The RASGRP family is composed of RAS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c76191fbfed1bf1fd91a2a6d39e000
http://europepmc.org/articles/PMC8537898

Identification of the Probable Site of Choleragen-Catalyzed ADP-Ribosylation in a Goα-Like Protein Based on cDNA Sequence

Autor: Angus, C. William, Van Meurs, Krisa P., Tsai, Su-Chen, Adamik, Ronald, Miedel, May Chang, Pan, Yu-Ching E., Kung, Hsiang-Fu, Moss, Joel, Vaughan, Martha

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 1986 Aug . 83(16), 5813-5816.

Externí odkaz: https://www.jstor.org/stable/28042

The Roles of Diacylglycerol Kinase α in Cancer Cell Proliferation and Apoptosis

Autor: Daisuke Takahashi, Fumi Hoshino, Fumio Sakane, Hiromichi Sakai, Masayuki Ebina

Publikováno v: Cancers
Cancers, Vol 13, Iss 5190, p 5190 (2021)

Simple Summary Diacylglycerol (DG) kinase (DGK) phosphorylates DG to generate phosphatidic acid (PA). DGKα is highly expressed in several refractory cancer cells, including melanoma, hepatocellular carcinoma, and glioblastoma cells, attenuates apopt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554dd244501865b409c2e19d8899aed6
https://doi.org/10.3390/cancers13205190

RasGRP1 induces autophagy and transformation-associated changes in primary human keratinocytes

Autor: James Turkson, Dirk Geerts, Joe W. Ramos, Lauren L. Fonseca, Junfang Ji, Won Seok Yang

Publikováno v: Translational oncology, 14(1):100880. Neoplasia Press
Translational Oncology
Translational Oncology, Vol 14, Iss 1, Pp 100880-(2021)
Fonseca, L L, Yang, W S, Geerts, D, Turkson, J, Ji, J & Ramos, J W 2021, ' RasGRP1 induces autophagy and transformation-associated changes in primary human keratinocytes ', Translational Oncology, vol. 14, no. 1, pp. 100880 . https://doi.org/10.1016/j.tranon.2020.100880
Translational Oncology, 14(1). Neoplasia Press

Ras mutations are present in only a subset of sporadic human cutaneous squamous cell carcinomas (cSCC) even though Ras is activated in most. This suggests that other mechanisms of Ras activation play a role in the disease. The aberrant expression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9dc6443dde78075106ecb9cb2603d91
https://doi.org/10.1016/j.tranon.2020.100880

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