Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Guanwei Fan"'
Autor:
Zhihao Liu, Xiyun Bian, Lan Li, Li Liu, Chao Feng, Ying Wang, Jingyu Ni, Sheng Li, Dading Lu, Yanxia Li, Chuanrui Ma, Tian Yu, Xiaolin Xiao, Na Xue, Yuxiang Wang, Chunyan Zhang, Xiaofang Ma, Xiumei Gao, Xiaohui Fan, Xiaozhi Liu, Guanwei Fan
Publikováno v:
Advanced Science, Vol 11, Iss 34, Pp n/a-n/a (2024)
Abstract Myocardial infarction (MI) triggers a poor ventricular remodeling response, but the underlying mechanisms remain unclear. Here, the authors show that sentrin‐specific protease 1 (SENP1) is downregulated in post‐MI mice and in patients wi
Externí odkaz:
https://doaj.org/article/01008cc38a86416785ef581069395e74
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Effective components and related target genes of Folium Artemisiae argyi were screened from Traditional Chinese Medicines for Systems Pharmacology Database and Analysis Platform. The therapeutic targets of atherosclerosis were searched in th
Externí odkaz:
https://doaj.org/article/33eb88364fe9498394b88c3bb4f151bf
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115553- (2023)
Although telomerase has low activity in somatic quiescent cells, it plays an significant roles in regenerative cells such as endothelial cells, hepatocytes, epithelial cells, and hemocytes. Telomerase activity and telomere length are critical factors
Externí odkaz:
https://doaj.org/article/f0cca28f1f43495f98962ca02fa25ea5
Autor:
Zhihao Liu, Xiaozhi Liu, Li Liu, Ying Wang, Jie Zheng, Lan Li, Sheng Li, Han Zhang, Jingyu Ni, Chuanrui Ma, Xiumei Gao, Xiyun Bian, Guanwei Fan
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 2, Pp 170-186 (2023)
Small ubiquitin-related modifier (SUMOylation) is a dynamic post-translational modification that maintains cardiac function and can protect against a hypertrophic response to cardiac pressure overload. However, the function of SUMOylation after myoca
Externí odkaz:
https://doaj.org/article/c7bcf14449bc4efb9f532ee1232e2d78
Autor:
Jingyu Ni, Hao Zhang, Xiaodan Wang, Zhihao Liu, Tong Nie, Lan Li, Jing Su, Yan Zhu, Chuanrui Ma, Yuting Huang, Jingyuan Mao, Xiumei Gao, Guanwei Fan
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-12 (2022)
Abstract The failing heart is characterized by an increase in glucose uptake and glycolytic rates that is not accompanied by a concomitant increase in glucose oxidation. Lower coupling of glucose oxidation to glycolysis possibly owes to unchanged or
Externí odkaz:
https://doaj.org/article/ff3b455594ed4c14af3ca200a49b107b
Autor:
Siwen Fan, Guangxu Xiao, Jingyu Ni, Yuhan Zhao, Hongying Du, Yingran Liang, Ming Lv, Shuang He, Guanwei Fan, Yan Zhu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114642- (2023)
Background: Heart failure (HF) is a cardiovascular disease with high morbidity and mortality. Guanxinning injection (GXNI) is clinically used for the treatment of coronary heart disease, but its therapeutic efficacy and potential mechanism for HF are
Externí odkaz:
https://doaj.org/article/9a675dfd617f4cf3a95507108468d90a
Autor:
Lan Li, Jiasong Cao, Sheng Li, Tianyi Cui, Jingyu Ni, Han Zhang, Yan Zhu, Jingyuan Mao, Xiumei Gao, Adam C. Midgley, Meifeng Zhu, Guanwei Fan
Publikováno v:
Advanced Science, Vol 10, Iss 14, Pp n/a-n/a (2023)
Abstract Tissue‐resident cardiac macrophage subsets mediate cardiac tissue inflammation and repair after acute myocardial infarction (AMI). CC chemokine receptor 2 (CCR2)‐expressing macrophages have phenotypical similarities to M1‐polarized mac
Externí odkaz:
https://doaj.org/article/61c7a69b309949ab967fa1c75e9c0e4c
Autor:
Shu Yang, Jiaqing Xiang, Chuanrui Ma, Guangyan Yang, Xinyu Wang, Hanyong Liu, Guanwei Fan, Lin Kang, Zhen Liang
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112367- (2023)
Summary: Transforming growth factor β (TGF-β) is the primary factor that drives fibrosis in most forms of chronic kidney disease. The aim of this study was to identify endogenous regulators of TGF-β signaling and fibrosis. Here, we show that tubul
Externí odkaz:
https://doaj.org/article/21b743ff816b4518860d90c994cdbac3
Autor:
Jingyu Ni, Zhihao Liu, Miaomiao Jiang, Lan Li, Jie Deng, Xiaodan Wang, Jing Su, Yan Zhu, Feng He, Jingyuan Mao, Xiumei Gao, Guanwei Fan
Publikováno v:
Journal of Ginseng Research, Vol 46, Iss 2, Pp 235-247 (2022)
Background: Ginsenoside Rg3 is one of the main active ingredients in ginseng. Here, we aimed to confirm its protective effect on the heart function in transverse aortic coarctation (TAC)-induced heart failure mice and explore the potential molecular
Externí odkaz:
https://doaj.org/article/a177a8f55b324a59b11277fee28e8a4e
Autor:
Ming Lyu, Guanwei Fan, Guangxu Xiao, Taiyi Wang, Dong Xu, Jie Gao, Shaoqin Ge, Qingling Li, Yuling Ma, Han Zhang, Jigang Wang, Yuanlu Cui, Junhua Zhang, Yan Zhu, Boli Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 11, Pp 3337-3363 (2021)
COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread across the globe, posing an enormous threat to public health and safety. Traditional Chinese medicine (TCM), in combination with Western medicine (WM)
Externí odkaz:
https://doaj.org/article/d909b2e6af714b7eb33733072f004363