Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Guanqiao Wang"'
Autor:
Tengli Liu, Peng Sun, Jiaqi Zou, Le Wang, Guanqiao Wang, Na Liu, Yaojuan Liu, Xuejie Ding, Boya Zhang, Rui Liang, Shusen Wang, Zhongyang Shen
Publikováno v:
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background NKX6.1 is a transcription factor for insulin, as well as a marker for β cell maturity. Abnormal NKX6.1 expression in β cells, such as translocation from the nucleus to cytoplasm or lost expression, has been shown as a marker for
Externí odkaz:
https://doaj.org/article/7be8b0530fb243a7a5bbdf8ea9035c60
Autor:
Rui Liang, Na Liu, Guanqiao Wang, Peng Sun, Yaojuan Liu, Jiaqi Zou, Le Wang, Xuejie Ding, Boya Zhang, Zhongyang Shen, Tengli Liu, Shusen Wang
Publikováno v:
European Journal of Inflammation, Vol 19 (2021)
β cell dedifferentiation is a key mechanism for β cell dysfunction in type 2 diabetes mellitus (T2DM). Although it has been indicated in previous studies that β cell dedifferentiation could be induced by inflammation, the cytohistologic analyses o
Externí odkaz:
https://doaj.org/article/b4f7b631809044f380ba9b790386298d
Autor:
Le Wang, Tengli Liu, Rui Liang, Guanqiao Wang, Yaojuan Liu, Jiaqi Zou, Na Liu, Boya Zhang, Yan Liu, Xuejie Ding, Xiangheng Cai, Zhiping Wang, Xiumin Xu, Camillo Ricordi, Shusen Wang, Zhongyang Shen
Publikováno v:
EBioMedicine, Vol 51, Iss , Pp - (2020)
Background: A physiological hallmark of patients with type 2 diabetes mellitus (T2DM) is β cell dysfunction. Despite adequate treatment, it is an irreversible process that follows disease progression. Therefore, the development of novel therapies th
Externí odkaz:
https://doaj.org/article/5857bda823ef4772ad650b7a655cf302
Autor:
Yi Huan, Qian Jiang, Gang Li, Guoliang Bai, Tian Zhou, Shuainan Liu, Caina Li, Quan Liu, Sujuan Sun, Miaomiao Yang, Nan Guo, Xing Wang, Shusen Wang, Yaojuan Liu, Guanqiao Wang, Haihong Huang, Zhufang Shen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Glucagon like peptide-1 (GLP-1) plays a vital role in glucose homeostasis and sustaining β-cell function. Currently there are two major methods to enhance endogenous GLP-1 activity; inhibiting dipeptidyl peptidase-4 (DPP4) or activating G p
Externí odkaz:
https://doaj.org/article/b7cf3b9f7d1d47d2a96769334b00ea7b
Publikováno v:
Journal of Advanced Research in Education. 2:28-33
Parental attitude is one of the important factors to promote the formation of the long-term mechanism of the double reduction policy (DRP). By exerting ABC Model, the questionnaire and interview are designed to investigate the attitudes and influenci
Autor:
Jiaqi Zou, Peng Sun, Le Wang, Tengli Liu, Shusen Wang, Guanqiao Wang, Xuejie Ding, Zhongyang Shen, Yaojuan Liu, Boya Zhang, Rui Liang, Na Liu
Publikováno v:
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-7 (2021)
BMC Endocrine Disorders
BMC Endocrine Disorders
Background NKX6.1 is a transcription factor for insulin, as well as a marker for β cell maturity. Abnormal NKX6.1 expression in β cells, such as translocation from the nucleus to cytoplasm or lost expression, has been shown as a marker for β cell
Autor:
Bradley Haltli, Henrik Stryhn, Hebelin Correa, Douglas H. Marchbank, Guanqiao Wang, Russell G. Kerr, Libang Liang
Publikováno v:
Journal of Natural Products. 83:2696-2705
Co-cultivation has been used as a promising tool to turn on or up-regulate cryptic biosynthetic pathways for microbial natural product discovery. Recently, a modified culturing strategy similar to co-cultivation was investigated, where heat-killed in
Autor:
Guanqiao Wang, Boya Zhang, Le Wang, Yaojuan Liu, Na Liu, Shusen Wang, Xue Liang, Rui Liang, Xuejie Ding, Tengli Liu, Leisheng Zhang, Jiaqi Zou
Publikováno v:
International Journal of Stem Cells
Background and objectives Adipose tissue-derived mesenchymal stem cells (ASCs) are recognized as an advantaged source for the prevention and treatment of diverse diseases including type 2 diabetes mellitus (T2DM). However, alterations in characterist
Autor:
Xuejie Ding, Chenxi Lu, Peng Sun, Guanqiao Wang, Shusen Wang, Jiaqi Zou, Zhongyang Shen, Na Liu, Rui Liang, Le Wang, Tengli Liu, Yaojuan Liu, Xue Liang
Publikováno v:
Pancreas. 49:692-698
Objectives The present study aimed to investigate the dynamic change of α cells and β cells, and their ratios in prediabetes and type 2 diabetes in the Chinese population. Methods Pancreata from 27 nondiabetic (ND), 8 prediabetic (PreD), and 19 typ
Autor:
Peng Sun, Shusen Wang, Na Liu, Yaojuan Liu, Jiaqi Zou, Boya Zhang, Rui Liang, Guanqiao Wang, Tengli Liu, Xuejie Ding, Xiangheng Cai, Le Wang
Publikováno v:
Biochemical and Biophysical Research Communications. 523:382-388
Hypoxia affects the function of pancreatic β cells, and the molecular mechanism underlying hypoxia-related β cell dysfunction in human type 2 diabetes mellitus (T2DM) remains to be elucidated. In this study, by comparing the gene expression profile