Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Guanqi Dai"'
Autor:
WeiChao Hao, MeiJuan Dian, Ying Zhou, QiuLing Zhong, WenQian Pang, ZiJian Li, YaYan Zhao, JiaCheng Ma, XiaoLin Lin, RenRu Luo, YongLong Li, JunShuang Jia, HongFen Shen, ShiHao Huang, GuanQi Dai, JiaHong Wang, Yan Sun, Dong Xiao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
The role of eiptranscriptomic modifications in autophagy is unclear. Here, the authors show that the m6A reader YTHDF3 functions as a nutrient responder to recognize upregulated m6A modification, promoting FOXO3 translation to subsequently initiate a
Externí odkaz:
https://doaj.org/article/6aeae5d88b614d939095da1e25d0cb93
Autor:
Zhenghui Song, Xinhui Liu, Wan Zhang, Yue Luo, Hua Xiao, Yun Liu, Guanqi Dai, Jian Hong, Aimin Li
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background JAK1 and JAK2 have been implicated in fibrosis and cancer as a fibroblast-related marker; however, their role in liver fibrosis has not been elucidated. Here, we aim to determine the effect and underlying mechanism of JAK1/2 inhib
Externí odkaz:
https://doaj.org/article/eed1d80e7030457185b0af332827acee
Autor:
Peng Chen, Xiaojun Luo, Guanqi Dai, Yuchuan Jiang, Yue Luo, Shuang Peng, Hao Wang, Penghui Xie, Chen Qu, Wenyu Lin, Jian Hong, Xue Ning, Aimin Li
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 7, Pp 1062-1074 (2020)
Liver cancer: Common anesthetic can accelerate tumor progression Researchers warn against using the anesthetic dexmedetomidine (DEX) in liver cancer patients after indications that it promotes tumor growth. Concerns have been raised that certain anes
Externí odkaz:
https://doaj.org/article/80f5f3dfe91b425cb22d2f4e052fdd0c
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The onset of liver cancer is insidious. Currently, there is no effective method for the early detection of hepatocellular carcinoma (HCC). Transcriptomic profiles of 826 tissue samples from the Gene Expression Omnibus (GEO), The Cancer Genome Atlas (
Externí odkaz:
https://doaj.org/article/558a9841b46341e7a844fa67e60ee51a
Autor:
Guanqi Dai, Yonglong Li, Shihao Huang, Xueyi Tu, Zhihao Zhou, Wanyi Chen, Jintao Lin, Yingchun Li, Danhua He, Taoyan Lin, Jinge Cong, Ye Lei, Jiawei Xia, Liuxin Han, Zhenxia Yao, Weiwei Liu, Ao Zhang, Ying Zhou, Qiwen Li, Jing Li, Aibing Wu, Dong Xiao, Junshuang Jia, Wentao Zhao, Xiaolin Lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be97bf69bad1298cd0506aa23e29e6fc
https://doi.org/10.2139/ssrn.4363559
https://doi.org/10.2139/ssrn.4363559
Autor:
Zhenghui Song, Wan Zhang, Aimin Li, Jian Hong, Guanqi Dai, Xinhui Liu, Hua Xiao, Yun Liu, Yue Luo
Publikováno v:
Journal of translational medicine. 20(1)
Background JAK1 and JAK2 have been implicated in fibrosis and cancer as a fibroblast-related marker; however, their role in liver fibrosis has not been elucidated. Here, we aim to determine the effect and underlying mechanism of JAK1/2 inhibition on
Autor:
Chen Qu, Hao Wang, Shuang Peng, Xue Ning, Jian Hong, Aimin Li, Wenyu Lin, Yue Luo, Peng Chen, Xiaojun Luo, Penghui Xie, Guanqi Dai, Yuchuan Jiang
Publikováno v:
Experimental & Molecular Medicine
Experimental and Molecular Medicine, Vol 52, Iss 7, Pp 1062-1074 (2020)
Experimental and Molecular Medicine, Vol 52, Iss 7, Pp 1062-1074 (2020)
Dexmedetomidine (DEX) is an anesthetic that is widely used in the clinic, and it has been reported to exhibit paradoxical effects in the progression of multiple solid tumors. In this study, we sought to explore the mechanism by which DEX regulates he
Autor:
WeiChao, Hao, MeiJuan, Dian, Ying, Zhou, QiuLing, Zhong, WenQian, Pang, ZiJian, Li, YaYan, Zhao, JiaCheng, Ma, XiaoLin, Lin, RenRu, Luo, YongLong, Li, JunShuang, Jia, HongFen, Shen, ShiHao, Huang, GuanQi, Dai, JiaHong, Wang, Yan, Sun, Dong, Xiao
Publikováno v:
Nature communications. 13(1)
Autophagy is crucial for maintaining cellular energy homeostasis and for cells to adapt to nutrient deficiency, and nutrient sensors regulating autophagy have been reported previously. However, the role of eiptranscriptomic modifications such as m
Publikováno v:
Cell biochemistry and functionREFERENCES. 38(7)
Long noncoding RNAs have been proved in regulating tumourigenesis, including hepatocellular carcinoma (HCC). However, up to date, the role of PCAT6 in HCC is rare to be reported. In current study, bioinformatics analysis and quantitative real-time PC
Autor:
Yuchuan Jiang, Jinying Li, Chen Qu, Wenyu Lin, Guanqi Dai, Jian Hong, Shuang Peng, Hui Yuan, Penghui Xie, Lu He, Raymond T. Chung, Kaishun Hu, Dandan Zheng, Mengxian Tu, Peng Chen
Publikováno v:
Journal of Cellular and Molecular Medicine
The pro‐inflammatory and pro‐fibrotic liver microenvironment facilitates hepatocarcinogenesis. However, the effects and mechanisms by which the hepatic fibroinflammatory microenvironment modulates intrahepatic hepatocellular carcinoma (HCC) progr