Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Guann-Yi Yu"'
Autor:
Pei-Ju Tsai, Ming-Yu Chen, Wei-Chan Hsu, Su-Fang Lin, Po-Chiang Chan, Hsin-Hsin Chen, Cheng-Yuan Kao, Wen-Jye Lin, Tsung-Hsien Chuang, Guann-Yi Yu, Yu-Wen Su
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110388- (2024)
Summary: Phosphatase and tensin homolog (PTEN) is vital for B cell development, acting as a key negative regulator in the PI3K signaling pathway. We used CD23-cre to generate PTEN-conditional knockout mice (CD23-cKO) to examine the impact of PTEN mut
Externí odkaz:
https://doaj.org/article/d812a20ceb854dd786b6517a2a8e0ad6
Autor:
Hsin-Wei Wang, Hsing-Han Li, Shih-Cheng Wu, Cheng-Kang Tang, Hui-Ying Yu, Ya-Chen Chang, Pei-Shan Sung, Wei-Liang Liu, Matthew P. Su, Guann-Yi Yu, Li-Rung Huang, Chun-Hong Chen, Shie-Liang Hsieh
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-16 (2023)
Abstract Background Zika virus (ZIKV) infection is clinically known to induce testicular swelling, termed orchitis, and potentially impact male sterility, but the underlying mechanisms remain unclear. Previous reports suggested that C-type lectins pl
Externí odkaz:
https://doaj.org/article/34f37a12112044d9964d59b65412f77f
Autor:
Hsing-Han Li, Matthew P. Su, Shih-Cheng Wu, Hsiao-Hui Tsou, Meng-Chun Chang, Yu-Chieh Cheng, Kuen-Nan Tsai, Hsin-Wei Wang, Guan-Hua Chen, Cheng-Kang Tang, Pei-Jung Chung, Wan-Ting Tsai, Li-Rung Huang, Yueh Andrew Yueh, Hsin-Wei Chen, Chao-Ying Pan, Omar S. Akbari, Hsiao-Han Chang, Guann-Yi Yu, John M. Marshall, Chun-Hong Chen
Publikováno v:
EBioMedicine, Vol 94, Iss , Pp 104723- (2023)
Summary: Background: Dengue virus outbreaks are increasing in number and severity worldwide. Viral transmission is assumed to require a minimum time period of viral replication within the mosquito midgut. It is unknown if alternative transmission per
Externí odkaz:
https://doaj.org/article/e6d7583013fd41b6a90b1e4f40db47b1
Autor:
Chen-Yi Chiang, Mei-Yu Chen, Chia-Wei Hsu, Chia-Yeh Liu, Yu-Wen Tsai, Hung-Chun Liao, Jia-Ying Yan, Zih-Shiuan Chuang, Hsin-I. Wang, Chien-Hsiung Pan, Chia-Yi Yu, Guann-Yi Yu, Ching-Len Liao, Shih-Jen Liu, Hsin-Wei Chen
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-13 (2022)
Abstract Background Calls for the coronavirus to be treated as an endemic illness, such as the flu, are increasing. After achieving high coverage of COVID-19 vaccination, therapeutic drugs have become important for future SARS-CoV-2 variant outbreaks
Externí odkaz:
https://doaj.org/article/c1304be9b1564f9aa844ddaedb028b06
Autor:
Kit Man Chai, Tsai-Teng Tzeng, Kuan-Yin Shen, Hung-Chun Liao, Jhe-Jhih Lin, Mei-Yu Chen, Guann-Yi Yu, Horng-Yunn Dou, Ching-Len Liao, Hsin-Wei Chen, Shih-Jen Liu
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 1, p e0011045 (2023)
[This corrects the article DOI: 10.1371/journal.pntd.0009374.].
Externí odkaz:
https://doaj.org/article/3a3e9c210a774c81beb0f2010bc6d3ae
Autor:
Chih-Feng Tien, Wan-Ting Tsai, Chun Hwa Chen, Hui-Ju Chou, Mingzi M. Zhang, Jhe-Jhih Lin, En-Ju Lin, Shih-Syong Dai, Yueh-Hsin Ping, Chia-Yi Yu, Yi-Ping Kuo, Wei-Hsiang Tsai, Hsin-Wei Chen, Guann-Yi Yu
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104709- (2022)
Summary: Post-translational modifications (PTMs), such as glycosylation and palmitoylation, are critical to protein folding, stability, intracellular trafficking, and function. Understanding regulation of PTMs of SARS-CoV-2 spike (S) protein could he
Externí odkaz:
https://doaj.org/article/7e8eaed9e1394cfe84ce788de24baf0c
Autor:
Jhe-Jhih Lin, Chih-Feng Tien, Yi-Ping Kuo, En-Ju Lin, Wei-Hsiang Tsai, Ming-Yu Chen, Pei-Ju Tsai, Yu-Wen Su, Nikhil Pathak, Jinn-Moon Yang, Chia-Yi Yu, Zih-Shiuan Chuang, Han-Chieh Wu, Wan-Ting Tsai, Shih-Syong Dai, Hung-Chun Liao, Kit Man Chai, Yu-Siang Su, Tsung-Hsien Chuang, Shih-Jen Liu, Hsin-Wei Chen, Horng-Yunn Dou, Feng-Jui Chen, Chiung-Tong Chen, Chin-Len Liao, Guann-Yi Yu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
An effective COVID-19 vaccine against broad SARS-CoV-2 variants is still an unmet need. In the study, the vesicular stomatitis virus (VSV)-based vector was used to express the SARS-CoV-2 Spike protein to identify better vaccine designs. The replicati
Externí odkaz:
https://doaj.org/article/fa17117b647a4767b928f824372d20e3
Autor:
Mei-Yu Chen, Kit Man Chai, Chen-Yi Chiang, Chiao-Chieh Wu, Guann-Yi Yu, Shih-Jen Liu, Hsin-Wei Chen
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-11 (2020)
Abstract Background The emergence of Zika virus (ZV) in tropical and subtropical areas of the world has created an urgent need for vaccines against ZV. However, approved vaccines that prevent ZV infection are not available. To develop an effective va
Externí odkaz:
https://doaj.org/article/6d454401d5cd490a85f65a5c5bd083bb
Autor:
Hui-Min Ho, Chiung-Yi Huang, Chung-Hsiang Yang, Shih-Jen Liu, Hsin-Wei Chen, Guann-Yi Yu, Jen-Kun Chen, Tsung-Hsien Chuang, Ming-Hsi Huang
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2539 (2022)
Nasal spray vaccination is viewed as a promising strategy for inducing both mucosal and systemic protection against respiratory SARS-CoV-2 coronavirus. Toward this goal, a safe and efficacious mucosal adjuvant is necessary for the transportation of t
Externí odkaz:
https://doaj.org/article/012c7998f3eb42ac851354e4eb536b15
Autor:
Kit Man Chai, Tsai-Teng Tzeng, Kuan-Yin Shen, Hung-Chun Liao, Jhe-Jhih Lin, Mei-Yu Chen, Guann-Yi Yu, Horng-Yunn Dou, Ching-Len Liao, Hsin-Wei Chen, Shih-Jen Liu
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 5, p e0009374 (2021)
The development of efficient vaccines against COVID-19 is an emergent need for global public health. The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major target for the COVID-19 vaccine. To quickly respond to t
Externí odkaz:
https://doaj.org/article/ed966694d2fb48dfa78c64314db836a2