Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Guanling Huang"'
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
Research on air pollution, one of the most common environmental factors, has primarily focused on its effects on physical, mental, and cognitive health. However, air pollution-induced achromatic color of an environment, which is a prominent feature o
Externí odkaz:
https://doaj.org/article/a3f20e4172024b8a945d8c17fdb7370b
Autor:
Jiurong Liang, Guanling Huang, Xue Liu, Ningshan Liu, Forough Taghavifar, Kristy Dai, Changfu Yao, Nan Deng, Yizhou Wang, Peter Chen, Cory Hogaboam, Barry R Stripp, William C Parks, Paul W Noble, Dianhua Jiang
Publikováno v:
eLife, Vol 12 (2023)
Aging is a critical risk factor in idiopathic pulmonary fibrosis (IPF). Dysfunction and loss of type 2 alveolar epithelial cells (AEC2s) with failed regeneration is a seminal causal event in the pathogenesis of IPF, although the precise mechanisms fo
Externí odkaz:
https://doaj.org/article/dc36e141f9de42bfa03fa5b279b8212e
Autor:
Jiurong Liang, Guanling Huang, Xue Liu, Forough Taghavifar, Ningshan Liu, Yizhou Wang, Nan Deng, Changfu Yao, Ting Xie, Vrishika Kulur, Kristy Dai, Ankita Burman, Simon C. Rowan, S. Samuel Weigt, John Belperio, Barry Stripp, William C. Parks, Dianhua Jiang, Paul W. Noble
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 11 (2022)
Type 2 alveolar epithelial cells (AEC2s) function as progenitor cells in the lung. We have shown previously that failure of AEC2 regeneration results in progressive lung fibrosis in mice and is a cardinal feature of idiopathic pulmonary fibrosis (IPF
Externí odkaz:
https://doaj.org/article/f7539cbaaa2b4928beaa1bce4118eb7f
Autor:
Miriam S. Hohmann, David M. Habiel, Milena S. Espindola, Guanling Huang, Isabelle Jones, Rohan Narayanan, Ana Lucia Coelho, Justin M. Oldham, Imre Noth, Shwu-Fan Ma, Adrianne Kurkciyan, Jonathan L. McQualter, Gianni Carraro, Barry Stripp, Peter Chen, Dianhua Jiang, Paul W. Noble, William Parks, John Woronicz, Geoffrey Yarranton, Lynne A. Murray, Cory M. Hogaboam
Publikováno v:
JCI Insight, Vol 6, Iss 11 (2021)
Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant repair that diminishes lung function via mechanisms that remain poorly understood. CC chemokine receptor (CCR10) and its ligand CCL28 were both elevated in IPF compared with normal dono
Externí odkaz:
https://doaj.org/article/33394c66fec3438285f38cc27a7b8ace
Autor:
Xue Liu, Simon C. Rowan, Jiurong Liang, Changfu Yao, Guanling Huang, Nan Deng, Ting Xie, Di Wu, Yizhou Wang, Ankita Burman, Tanyalak Parimon, Zea Borok, Peter Chen, William C. Parks, Cory M. Hogaboam, S. Samuel Weigt, John Belperio, Barry R. Stripp, Paul W. Noble, Dianhua Jiang
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102551- (2021)
Summary: Pulmonary mesenchymal cells are critical players in both the mouse and human during lung development and disease states. They are increasingly recognized as highly heterogeneous, but there is no consensus on subpopulations or discriminative
Externí odkaz:
https://doaj.org/article/61fae4523109433c93b49fa80896a3e0
Autor:
Buqing Ye, Benyu Liu, Lu Hao, Xiaoxiao Zhu, Liuliu Yang, Shuo Wang, Pengyan Xia, Ying Du, Shu Meng, Guanling Huang, Xiwen Qin, Yanying Wang, Xinlong Yan, Chong Li, Junfeng Hao, Pingping Zhu, Luyun He, Yong Tian, Zusen Fan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Embryonic stem cell pluripotency depends upon precise regulation by a core transcription network. Here the authors show that polyglutamylation mediated stabilization of the transcription factor Klf4 by TTLL1 and TTLL4 promotes reprogramming, pluripot
Externí odkaz:
https://doaj.org/article/73012c1b32144569b6f62721f4a3512b
Autor:
Ting Xie, Yizhou Wang, Nan Deng, Guanling Huang, Forough Taghavifar, Yan Geng, Ningshan Liu, Vrishika Kulur, Changfu Yao, Peter Chen, Zhengqiu Liu, Barry Stripp, Jie Tang, Jiurong Liang, Paul W. Noble, Dianhua Jiang
Publikováno v:
Cell Reports, Vol 22, Iss 13, Pp 3625-3640 (2018)
Summary: Fibroblast heterogeneity has long been recognized in mouse and human lungs, homeostasis, and disease states. However, there is no common consensus on fibroblast subtypes, lineages, biological properties, signaling, and plasticity, which seve
Externí odkaz:
https://doaj.org/article/edd0b2cb8e314760a43c4107059cc9fc
Autor:
Buqing Ye, Benyu Liu, Liuliu Yang, Guanling Huang, Lu Hao, Pengyan Xia, Shuo Wang, Ying Du, Xiwen Qin, Pingping Zhu, Jiayi Wu, Nobuo Sakaguchi, Junyan Zhang, Zusen Fan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Haematopoiesis and the generation of lymphoid cell subsets are controlled by delicate genetic programs enforced via epigenetic regulation. Here the authors show that Pcid2 interacts with ZNHIT1, a component of the SRCAP chromatin remodelling complex,
Externí odkaz:
https://doaj.org/article/99b4f3c177f8426eb90c65ef0672f322
Autor:
Benyu Liu, Buqing Ye, Xiaoxiao Zhu, Guanling Huang, Liuliu Yang, Pingping Zhu, Ying Du, Jiayi Wu, Shu Meng, Yong Tian, Zusen Fan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Innate lymphoid cells (ILC) are important regulators of mucosal immunity, but how their development and homeostasis are modulated is still unclear. Here the authors show that the differentiation of group 3 ILCs is controlled by the glutamylation of I
Externí odkaz:
https://doaj.org/article/fdcc5a6db53a4add8f579c835b2349d1
Autor:
Pingping Zhu, Yanying Wang, Jiayi Wu, Guanling Huang, Benyu Liu, Buqing Ye, Ying Du, Guangxia Gao, Yong Tian, Lei He, Zusen Fan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Liver cancer stem cells (CSCs) may contribute to the high rate of recurrence of hepatocellular carcinoma. Here, the authors show that the long coding RNA, LcnBRM, regulates the self-renewal of liver CSCs and tumour initiation through binding to BAF c
Externí odkaz:
https://doaj.org/article/a14e02b6cfc44b4dbfedd36546c25516