Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Guanhua Lai"'
Publikováno v:
PLoS Genetics, Vol 19, Iss 12, p e1011102 (2023)
Acute lymphoblastic leukemia/lymphoma (ALL) is the most common pediatric cancer and is a malignancy of T or B lineage lymphoblasts. Dysregulation of intracellular Ca2+ levels has been observed in patients with ALL, leading to improper activation of d
Externí odkaz:
https://doaj.org/article/a8847c528dd041ef9bf13daa3f168aa8
Publikováno v:
Case Reports in Hematology, Vol 2019 (2019)
Hepatosplenic T-cell lymphomas (TCLs) are a rare, aggressive subset of TCLs, accounting for less than 5% of all peripheral T-cell and natural killer (NK) cell lymphomas. We report the case of a CD3 negative hepatosplenic T-cell lymphoma in a 42-year-
Externí odkaz:
https://doaj.org/article/9fcecf4463a7468aa38938e73712752d
Autor:
Yanyan Wang, Yun-Ling Tai, Derrick Zhao, Yuan Zhang, Junkai Yan, Genta Kakiyama, Xuan Wang, Emily C. Gurley, Jinze Liu, Jinpeng Liu, Jimin Liu, Guanhua Lai, Phillip B. Hylemon, William M. Pandak, Weidong Chen, Huiping Zhou
Publikováno v:
Cells, Vol 10, Iss 2, p 210 (2021)
Background and Aims: The disease progression of nonalcoholic fatty liver disease (NAFLD) from simple steatosis (NAFL) to nonalcoholic steatohepatitis (NASH) is driven by multiple factors. Berberine (BBR) is an ancient Chinese medicine and has various
Externí odkaz:
https://doaj.org/article/196a8eaf79bc4c698900c2d12f6a79c8
Publikováno v:
Journal of Shenzhen University Science and Engineering. 38:658-663
Autor:
Joseph Gillam, Aida Catic, Prabakaran Paulraj, Justin Dalton, Guanhua Lai, Colleen Jackson‐Cook, Scott Turner, Andrea Ferreira‐Gonzalez, Elizabeth Barrie
Publikováno v:
Genes, chromosomescancer. 61(8)
Non-Down-syndrome-related acute megakaryoblastic leukemia (non-DS-AMKL) is a rare form of leukemia that can present with a variety of initial symptoms, including fever, rash, bruising, bleeding, or other more clinically challenging symptoms. Herein,
Autor:
Phillip B. Hylemon, Huiping Zhou, Guang Liang, William M. Pandak, Runping Liu, Emily C. Gurley, Weidong Chen, Xiaojiaoyang Li, Xuan Wang, Derrick Zhao, Jasmohan S. Bajaj, Guanhua Lai, Yanyan Wang, H. Robert Lippman, Weiwei Zhu
Publikováno v:
Hepatology
Activation of hepatic stellate cells (HSCs) represents the primary driving force to promote the progression of chronic cholestatic liver diseases. We previously reported that cholangiocyte-derived exosomal long noncoding RNA-H19 (lncRNA-H19) plays a
Autor:
Phillip B. Hylemon, Huiping Zhou, Derrick Zhao, Yun-Ling Tai, Xuan Wang, Genta Kakiyama, Yuan Zhang, Guanhua Lai, Junkai Yan, Jimin Liu, Jinpeng Liu, William M. Pandak, Weidong Chen, Jinze Liu, Yanyan Wang, Emily C. Gurley
Publikováno v:
Cells, Vol 10, Iss 210, p 210 (2021)
Cells
Volume 10
Issue 2
Cells
Volume 10
Issue 2
The disease progression of nonalcoholic fatty liver disease (NAFLD) from simple steatosis (NAFL) to nonalcoholic steatohepatitis (NASH) is driven by multiple factors. Berberine (BBR) is an ancient Chinese medicine and has various beneficial effects o
Autor:
Hongliang He, Hu Yang, Zhiming Huang, Phillip B. Hylemon, Huiping Zhou, Xiaojiaoyang Li, Xuan Wang, Luyong Zhang, Guanhua Lai, Melanie B. White, William M. Pandak, Juan Wang, Jasmohan S. Bajaj, Emily C. Gurley, Runping Liu
Publikováno v:
Hepatology. 68:599-615
Cholestatic liver injury is an important clinical problem with limited understanding of disease pathologies. Exosomes are small extracellular vesicles released by a variety of cells including cholangiocytes. Exosome-mediated cell-cell communication c
Autor:
Arun J. Sanyal, Phillip B. Hylemon, Bhagyalaxmi Sukka Ganesh, Huiping Zhou, Guanhua Lai, Derrick Zhao, William M. Pandak, Zhiming Huang, Jasmohan S. Bajaj, Xiaojiaoyang Li, Runping Liu
Publikováno v:
Hepatology. 67:1441-1457
Impaired intestinal barrier function promotes the progression of various liver diseases including cholestatic liver disease. The close association of primary sclerosing cholangitis (PSC) with inflammatory bowel disease highlights the importance of th
Autor:
Emily C. Gurley, Runping Liu, Phillip B. Hylemon, Zhiming Huang, Guanhua Lai, Jing Yang, Huiping Zhou, Puneet Puri, William M. Pandak, Luyong Zhang, Yuping Tang, Lixin Sun, Xiaojiaoyang Li, Zhenzhou Jiang
Publikováno v:
Hepatology. 66:869-884
The multidrug resistance 2 knockout (Mdr2-/- ) mouse is a well-established model of cholestatic cholangiopathies. Female Mdr2-/- mice develop more severe hepatobiliary damage than male Mdr2-/- mice, which is correlated with a higher proportion of tau