Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Guanhua, Song"'
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 4, Pp n/a-n/a (2023)
Abstract Introduction Drug development has been challenged by the dual drawbacks involving unpredictable disease outcomes and drug resistance, which has placed greater demands on pharmacology education. Molecular pharmacology, as a frontier crossover
Externí odkaz:
https://doaj.org/article/e9c7d4657b5040b18fbae52b84164935
Autor:
Tingting Feng, Jing Wang, Kai Cheng, Qiqi Lu, Ru Zhao, Shiguan Wang, Qingyun Zhang, Luna Ge, Jihong Pan, Guanhua Song, Lin Wang
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 7, Pp 1008-1028 (2022)
Objective: Androgen deprivation therapy (ADT) is still the principal treatment option for prostate cancer (PCa). In addition to reactivation of androgen receptor signaling, the resistance of PCa to apoptosis during ADT also contributes to castration
Externí odkaz:
https://doaj.org/article/979e42fe4ea649c1aa6c8989b9425064
Autor:
Luna Ge, Ting Wang, Dandan Shi, Yun Geng, Huancai Fan, Ruojia Zhang, Yuang Zhang, Jianli Zhao, Shufeng Li, Yi Li, Haojun Shi, Guanhua Song, Jihong Pan, Lin Wang, Jinxiang Han
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectiveThe contribution of activating transcription factor 6α (ATF6α) in rheumatoid arthritis (RA) pathogenesis, especially on fibroblast-like synoviocytes (FLSs), has been suggested by its sensitivity to inflammatory stimulus. However, the exact
Externí odkaz:
https://doaj.org/article/ae5b44d1a5fb497f910fd1933f71e82a
Autor:
Yi Han, Jinguang Wang, Shufeng Li, Yi Li, Yongli Zhang, Ruojia Zhang, Yuang Zhang, Huancai Fan, Haojun Shi, Jihong Pan, Guanhua Song, Luna Ge, Lin Wang
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-11 (2021)
Abstract Background Isopsoralen (IPRN), one of the active ingredients of Psoralea corylifolia Linn, has anti-inflammatory properties. We attempted to investigate the inhibitory effects of IPRN on rheumatoid arthritis (RA) and characterize its potenti
Externí odkaz:
https://doaj.org/article/d94f9e306af74873b127fb4aa1bd7ac4
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 4, Pp n/a-n/a (2022)
Abstract In the process of pharmacology education, practical teaching is an important complement to theoretical teaching. These activities include the use of experimental animals to obtain certain pharmacological parameters or to help students unders
Externí odkaz:
https://doaj.org/article/7ebac3a4012f4452a28924769d2b2254
Autor:
Xiaomei Yang, Qingwei Guo, Tingting Feng, Qiqi Lu, Luna Ge, Jihong Pan, Kehong Bi, Li Qiao, Lei Tian, Tianhua Xie, Chengfang Yao, Guanhua Song, Lin Wang
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-10 (2020)
Abstract Background Endoplasmic reticulum (ER) stress is closely related with the pathological progression of rheumatoid arthritis (RA), and fibroblast-like synoviocytes (FLSs) are known as its resistance against ER stress-induced apoptosis. Studies
Externí odkaz:
https://doaj.org/article/4c08a29632bc4ed6b24c83f4f49132e0
Autor:
Guanhua Song, Qiqi Lu, Hua Fan, Xiumei Zhang, Luna Ge, Ruisong Tian, Shiguan Wang, Tingting Feng, Jihong Pan, Jingjing Feng, Yabo Xiao, Xin Yi, Ningxin Ren, Lin Wang
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-11 (2019)
Abstract Introduction Abnormal glycolytic metabolism contributes to joint inflammation and destruction in rheumatoid arthritis (RA). We examine the expression and function of hexokinases in RA and evaluate the potential of their specific inhibitor fo
Externí odkaz:
https://doaj.org/article/b2b26646dbbd40e481c31c7c45b38400
Autor:
Qingyun Zhang, Xuehong Lin, Weiqi Wang, Xiaofan Zhang, Mengxue Lü, Zhurui Shao, Dandan Shi, Ruojia Zhang, Haojun Shi, Yuang Zhang, Jihong Pan, Guanhua Song, Kai Cheng, Luna Ge, Lin Wang, Jinxiang Han
Publikováno v:
Molecular Imaging and Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d3113da9e864f2abd4f48fa5d2447a0
https://doi.org/10.1007/s11307-023-01817-6
https://doi.org/10.1007/s11307-023-01817-6
Publikováno v:
Industrial Lubrication and Tribology, 2016, Vol. 68, Issue 2, pp. 242-249.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/ILT-07-2015-0100
Autor:
Ru Zhao, Ye Lv, Tingting Feng, Ruojia Zhang, Luna Ge, Jihong Pan, Bo Han, Guanhua Song, Lin Wang
Publikováno v:
The Prostate. 82:617-629
Despite the clinical success of androgen receptor (AR)-targeted therapies, prostate cancer (PCa) inevitably progresses to castration-resistant prostate cancer (CRPC). Transcription factor 6 α (ATF6α), an effector of the unfolded protein response (U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b561a83dabff256d1e6ca5608e7cef2
https://doi.org/10.1002/pros.24308
https://doi.org/10.1002/pros.24308