Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Guanheng Yang"'
Autor:
Yanan Chi, Guanheng Yang, Chuanliang Guo, Shaoqing Zhang, Lei Hong, Huixiang Tang, Xiao Sang, Jie Wang, Ji Ma, Yan Xue, Fanyi Zeng
Publikováno v:
Life, Vol 13, Iss 11, p 2157 (2023)
Hematopoietic stem cells (HSCs) are stem cells that can differentiate into various blood cells and have long-term self-renewal capacity. At present, HSC transplantation is an effective therapeutic means for many malignant hematological diseases, such
Externí odkaz:
https://doaj.org/article/cf634fd033904d39b93969ffab7af520
Autor:
Yunjie Wang, Zexu Li, Guanheng Yang, Linlin Cai, Fan Yang, Yaqiong Zhang, Yitao Zeng, Qingwen Ma, Fanyi Zeng
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Down's syndrome (DS) is one of the most commonly known disorders with multiple congenital disabilities. Besides severe cognitive impairment and intellectual disability, individuals with DS also exhibit additional phenotypes of variable penetrance and
Externí odkaz:
https://doaj.org/article/eca4fb15d14849ffaffb3a746fe6b341
Autor:
Guanheng Yang, Wansheng Shi, Xingyin Hu, Jingzhi Zhang, Zhijuan Gong, Xinbing Guo, Zhaorui Ren, Fanyi Zeng
Publikováno v:
Haematologica, Vol 99, Iss 8 (2014)
Although β-thalassemia is one of the most common human genetic diseases, there is still no effective treatment other than bone marrow transplantation. Induced pluripotent stem cells have been considered good candidates for the future repair or repla
Externí odkaz:
https://doaj.org/article/e07b98f632e3408ab653df0eda283a6c
Publikováno v:
Cell Proliferation. 55
Mesoderm, derived from a new layer between epiblast and hypoblast during gastrulation, can differentiate into various tissues, including muscles, bones, kidneys, blood, and the urogenital system. However, systematic elucidation of mesoderm characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eecb0fedb90d80bc374431898aa64e9
https://doi.org/10.1111/cpr.13298
https://doi.org/10.1111/cpr.13298
Publikováno v:
Cell Biology International. 45:1383-1392
Mental retardation is the main clinical manifestation of Down syndrome (DS), and neural abnormalities occur during the early embryonic period and continue throughout life. Tc1, a model mouse for DS, carries the majority part of the human chromosome 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baaee99e90c4cf0273cfbfda0ec84028
https://doi.org/10.1002/cbin.11560
https://doi.org/10.1002/cbin.11560
Autor:
Rui Ma, Guanheng Yang, Yanghe Fu, Xinqing Lu, Wang Qiuyue, Weidong Zhu, Chen Yufang, Deng Ping
Publikováno v:
ChemCatChem. 12:4930-4938
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::282643a10ddbd7af262e73d9c04c1273
https://doi.org/10.1002/cctc.202000712
https://doi.org/10.1002/cctc.202000712
Publikováno v:
Balkan Journal of Medical Genetics, Vol 23, Iss 1, Pp 5-13 (2020)
Balkan Journal of Medical Genetics : BJMG
Balkan Journal of Medical Genetics : BJMG
Induced pluripotent stem cells (iPSCs), generated from somatic cells, not only possess similar characteristics with embryonic stem cells (ESCs), but also present more advantages than ESCs in medical applications. The classical induction method that u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc5785961e7f8e48d7d5308b4d7bbed
https://doaj.org/article/adec4644a73f442e9f8aa89fda486b18
https://doaj.org/article/adec4644a73f442e9f8aa89fda486b18
Autor:
Yudan Fang, Dan Lu, Yiwen Zhu, Jingzhi Zhang, Yan Cheng, Xiuli Gong, Xiao Sang, Shuyue Fan, Guanheng Yang, Fanyi Zeng, Zhijuan Gong
OBJECTIVES: This study explored whether TALENs‐mediated non‐homologous end joining (NHEJ) targeting the mutation site can correct the aberrant β‐globin RNA splicing, and ameliorate the β‐thalassaemia phenotype in β(654) mice. MATERIAL AND
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa92574f903e472f6a163a5367adbe3
https://europepmc.org/articles/PMC6528953/
https://europepmc.org/articles/PMC6528953/
Autor:
Zhao-Rui Ren, Zhijuan Gong, Xingyin Hu, Fanyi Zeng, Xinbing Guo, Guanheng Yang, Wansheng Shi, Jingzhi Zhang
Publikováno v:
Haematologica. 99:1304-1311
Although β-thalassemia is one of the most common human genetic diseases, there is still no effective treatment other than bone marrow transplantation. Induced pluripotent stem cells have been considered good candidates for the future repair or repla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbac7645a0debb14551d14574238c4e
https://doi.org/10.3324/haematol.2013.087916
https://doi.org/10.3324/haematol.2013.087916
Publikováno v:
Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 31(9)
Since Yamanaka successfully reprogrammed murine fibroblasts into iPSCs in 2006, iPSCs technology has drawn much attention worldwide. Although iPSCs provides tremendous possibilities for both basic research and regenerative medicine, it has meanwhile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4bf720730fdc26c0735738d4bcf4970
https://pubmed.ncbi.nlm.nih.gov/26955706
https://pubmed.ncbi.nlm.nih.gov/26955706