Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Guangzhi Hao"'
Autor:
Yuwei Han, Guangzhi Hao, Song Han, Tingzhun Zhu, Yushu Dong, Ligang Chen, Xinyu Yang, Xiaoming Li, Hai Jin, Guobiao Liang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectiveThis study aims to investigate the inhibitory effect of Polydatin (PD) on endoplasmic reticulum (ER) stress following subarachnoid hemorrhage (SAH) and to elucidate the underlying mechanisms.MethodsA standard intravascular puncture model was
Externí odkaz:
https://doaj.org/article/5c4c0df3ef8043be91ea03573af237e1
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Objective Sex differences in outcomes of patients with aneurysmal subarachnoid hemorrhage (aSAH) remain controversial. Therefore, the aim of this study was to investigate the sex differences in the prognosis of patients with aSAH. Methods Th
Externí odkaz:
https://doaj.org/article/4364b190c9da4446b42fd9e4c48a9d55
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115247- (2023)
Mitochondrial dysfunction, especially in terms of mitochondrial dynamics, has been reported to be closely associated with neuronal outcomes and neurological impairment in cerebral ischemia/hypoxia injury. Dynamin-related protein 1 (Drp1) is a cytopla
Externí odkaz:
https://doaj.org/article/61d3cfc0a52e4eb58b492e5c8cd4362f
Autor:
Yu Huan, Huilin Quan, Bo Jia, Guangzhi Hao, Zuolin Shi, Tianzi Zhao, Ying Yuan, Fang Yuan, Yushu Dong, Guobiao Liang
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
IntroductionNeuronal cell death is an important factor in the pathogenesis of acute high-altitude cerebral hypoxia; however, the underlying molecular mechanism remains unclear. In this study, we tested if high-altitude hypoxia (HAH) causes neuronal d
Externí odkaz:
https://doaj.org/article/33037ae6b2e64af9a3125c422ae2c617
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
ObjectiveIn clinical practice, nimodipine is used to control cerebral vasospasm (CVS), which is one of the major causes of severe disability and mortality in patients with aneurysmal subarachnoid hemorrhage (aSAH). However, the exact efficacy of nimo
Externí odkaz:
https://doaj.org/article/72e66dff64714a8aad2885c1cfa5f370
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Background: Subarachnoid hemorrhage (SAH) is a devastating disease which leads to high morbidity and mortality. Recent studies have indicated that, never in mitosis gene A-related expressed kinase 7 (NEK7), is involved in NLRP3 (NLR family, pyrin dom
Externí odkaz:
https://doaj.org/article/e9aebffe3c114a32869248d7ad478c03
Publikováno v:
Annals of Palliative Medicine. 11:240-249
Recurrent ischemic events in cerebrovascular disease present a difficult problem in clinical practice. The predictive value of cytochrome P450 2C19 (CYP2C19) gene polymorphism and high platelet reactivity for recurrent ischemic events in cerebrovascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e060f10969d295e10847478ce5fb9d5
https://doi.org/10.21037/apm-21-3775
https://doi.org/10.21037/apm-21-3775
Autor:
Dongdong, Liu, Yushu, Dong, Gen, Li, Zheng, Zou, Guangzhi, Hao, Hua, Feng, Pengyu, Pan, Guobiao, Liang
Publikováno v:
Turkish neurosurgery. 30(5)
To determine whether melatonin (MLT) mitigates white matter (WM) injury by attenuating NOD-like receptor family pyrin domain-containing 3 (NLRP3)-associated oligodendrocyte apoptosis after subarachnoid hemorrhage (SAH).SAH model C57BL/6J mice were cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df2a12454b058cbf76f63c90d32308ac
https://pubmed.ncbi.nlm.nih.gov/32705666
https://pubmed.ncbi.nlm.nih.gov/32705666
Autor:
Guangzhi Hao, Zheng Zou, Yushu Dong, Gen Li, Pengyu Pan, Hua Feng, Guobiao Liang, Dongdong Liu
Publikováno v:
Turkish Neurosurgery.
Aim To determine whether melatonin (MLT) mitigates white matter (WM) injury by attenuating NOD-like receptor family pyrin domain-containing 3 (NLRP3)-associated oligodendrocyte apoptosis after subarachnoid hemorrhage (SAH). Material and methods SAH m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b10210099971b86357a49d464297f18a
https://doi.org/10.5137/1019-5149.jtn.27986-19.3
https://doi.org/10.5137/1019-5149.jtn.27986-19.3
Autor:
Sizhe Feng, Yushu Dong, Yang Yang, Chenxi Lu, Zhenlong Xin, Xue Wu, Zihao Yu, Guangzhi Hao, Zheng Zou, Pengyu Pan
Publikováno v:
Seminars in cancer biology. 67(Pt 1)
The epithelial-mesenchymal transition (EMT) is a process of cell transformation under certain physiological and pathological states in which epithelial cells are transformed into mesenchymal cells with fibroblast-like properties, which confers upon t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c51045c28f99ad430aa6745374ce9d
https://pubmed.ncbi.nlm.nih.gov/31199986
https://pubmed.ncbi.nlm.nih.gov/31199986