Zobrazeno 1 - 10
of 33 406
pro vyhledávání: '"Guangyu An"'
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 51, Iss 6, Pp 419-425 (2024)
ObjectiveTo investigate the effects of doublecortin-like kinase 1 (DCLK1) on the malignant biological behaviors, such as proliferation, migration, and invasion, of A549 cell line and their corresponding mechanisms. MethodsDCLK1-overexpressing A549 ce
Externí odkaz:
https://doaj.org/article/d84278ec93f142d290045fb55b0fed70
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-17 (2023)
Abstract Triple-negative breast cancer (TNBC) exhibits the poorest outcomes among breast cancer subtypes due to the high heterogeneity and a lasting scarcity of effectual treatments. Targeted therapies based on molecular subtypes of TNBC are critical
Externí odkaz:
https://doaj.org/article/23cc9a3dfa0d43b1a7f2d1da9c00d749
Autor:
Rui Yan, Jianjian Li, Zeru Xiao, Xiaona Fan, Heshu Liu, Ying Xu, Ruya Sun, Jian Liu, Jiannan Yao, Guangyu An, Yan Shi, Yang Ge
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 2, Pp 463-485 (2023)
Background & Aims: Gastrointestinal cancer stem cell marker doublecortin-like kinase (DCLK1) is strongly associated with poor outcomes in colorectal cancer (CRC). Although DCLK1’s regulatory effect on the tumor immune microenvironment has been hypo
Externí odkaz:
https://doaj.org/article/804851869f124d039a197e9e7b3a5bd9
Autor:
Yuankai Shi, Lin Wu, Xinmin Yu, Puyuan Xing, Yan Wang, Jianying Zhou, Airong Wang, Jianhua Shi, Yi Hu, Ziping Wang, Guangyu An, Yong Fang, Sanyuan Sun, Caicun Zhou, Changli Wang, Feng Ye, Xingya Li, Junye Wang, Mengzhao Wang, Yunpeng Liu, Yanqiu Zhao, Ying Yuan, Jifeng Feng, Zhendong Chen, Jindong Shi, Tao Sun, Gang Wu, Yongqian Shu, Qisen Guo, Yi Zhang, Yong Song, Shucai Zhang, Yuan Chen, Wei Li, Hongrui Niu, Wenwei Hu, Lijun Wang, Jianan Huang, Yang Zhang, Ying Cheng, Zhengdong Wu, Bo Peng, Jiya Sun, Christoph Mancao, Yanqi Wang, Luyao Sun
Publikováno v:
Cancer Communications, Vol 42, Iss 12, Pp 1314-1330 (2022)
Abstract Background Treatment options for Chinese patients with locally advanced or metastatic squamous‐cell non‐small‐cell lung cancer (sqNSCLC) after failure of first‐line chemotherapy are limited. This study (ORIENT‐3) aimed to evaluate
Externí odkaz:
https://doaj.org/article/a9847e751fa7451686516ca46525e3f5
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e18515- (2023)
Externí odkaz:
https://doaj.org/article/ea8ea52a333141ffb3f7b198dd7371dd
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e15925- (2023)
Background: Immune checkpoint inhibitor (ICI) treatment has enhanced survival outcomes in clear cell renal cell carcinoma (ccRCC) patients. Nevertheless, the effectiveness of immunotherapy in ccRCC patients is restricted and we intended to develop an
Externí odkaz:
https://doaj.org/article/6c75832aac8f4d3aa76e73f673f2eef8
Autor:
Yan Wang, Fei Xu, Haiyan Xu, Shuyang Zhang, Liang Yang, Shufei Yu, Guangjian Yang, Duo Chen, Guangyu An
Publikováno v:
BMJ Open, Vol 13, Iss 3 (2023)
Objectives Based on the acknowledged organ-specific immune microenvironment, little is known regarding the efficacy of immunotherapy in patients with lung cancer according to metastatic sites. This meta-analysis aimed to explore the efficacy of immun
Externí odkaz:
https://doaj.org/article/bfd1c938eedd4d3cab83b1185c11790d
Publikováno v:
AIMS Mathematics, Vol 7, Iss 5, Pp 7519-7527 (2022)
In this paper, we prove that every local Lie derivation on von Neumann algebras is a Lie derivation; and we show that if M is a type I von Neumann algebra with an atomic lattice of projections, then every local Lie derivation on LS(M) is a Lie deriva
Externí odkaz:
https://doaj.org/article/18ec72d87de3430c972194e2162c2c6f
Autor:
Yin Guan, Yutong Wang, Hongxia Li, Jing Meng, Xia You, Xiaofeng Zhu, Qin Zhang, Tingting Sun, Chuang Qi, Guangyu An, Ying Fan, Binghe Xu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ERBB2 amplification is one of the most important and mature targets for HER2-targeted drug therapy. Somatic mutations of ERBB2 in the tyrosine kinase domain have been studied extensively, and play a role in response to anti-HER2 therapy among differe
Externí odkaz:
https://doaj.org/article/eabcbd28228240d5bac82fe6290de673
Effects of plasma nonuniformity on zero frequency zonal structure (ZFZS) excitation by drift Alfven wave (DAW) instabilities in toroidal plasmas are investigated using nonlinear gyrokinetic theory. The governing equations describing nonlinear interac
Externí odkaz:
http://arxiv.org/abs/2408.00324