Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Guangyan Xiong"'
Autor:
Sajedah M. Hindi, Jonghyun Shin, Yann S. Gallot, Alex R. Straughn, Adriana Simionescu-Bankston, Lubna Hindi, Guangyan Xiong, Robert P. Friedland, Ashok Kumar
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Myoblast fusion is essential for skeletal muscle development and regeneration. Here the authors show that MyD88 is upregulated during myogenesis and during muscle growth, signals via the NF-κB and Wnt pathways, and that its expression modulates myob
Externí odkaz:
https://doaj.org/article/618fe52d57e34274978244f35c4dbdb6
Autor:
Guangyan Xiong, Sajedah M Hindi, Aman K Mann, Yann S Gallot, Kyle R Bohnert, Douglas R Cavener, Scott R Whittemore, Ashok Kumar
Publikováno v:
eLife, Vol 6 (2017)
Regeneration of skeletal muscle in adults is mediated by satellite stem cells. Accumulation of misfolded proteins triggers endoplasmic reticulum stress that leads to unfolded protein response (UPR). The UPR is relayed to the cell through the activati
Externí odkaz:
https://doaj.org/article/fac93d24e52749a8beb98981ad45d0b4
Autor:
Isabel Monroy, Anthony Park, Colin Cook, Guangyan Xiong, Vivien Chan, Cheng Liu, Saul Priceman, Monil Shah, Nimali Withana, Leslie Chong, Yuman Fong
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c71d249ba3a85a26a2eb86768b4427d3
https://doi.org/10.1136/jitc-2022-sitc2022.0368
https://doi.org/10.1136/jitc-2022-sitc2022.0368
Publikováno v:
Journal of Molecular Cell Biology. 11:53-66
Skeletal muscle regeneration in adults is attributed to the presence of satellite stem cells that proliferate, differentiate, and eventually fuse with injured myofibers. However, the signaling mechanisms that regulate satellite cell homeostasis and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a8f60c6a2c72c2c45837bc3c059b37
https://doi.org/10.1093/jmcb/mjy053
https://doi.org/10.1093/jmcb/mjy053
MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice
Autor:
Kyle R. Bohnert, Sajedah M. Hindi, Yann S. Gallot, Guangyan Xiong, Alex R. Straughn, Ashok Kumar
Publikováno v:
Human Molecular Genetics. 27:3449-3463
Duchenne muscular dystrophy (DMD), caused by mutations in the dystrophin gene, leads to severe muscle wasting and eventual death of the afflicted individuals, primarily due to respiratory failure. Deficit in myofiber regeneration, potentially due to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e39d50066d636a7e0ef6428a155a905b
https://doi.org/10.1093/hmg/ddy258
https://doi.org/10.1093/hmg/ddy258
Autor:
Joseph D. McMillan, Yann S. Gallot, Kyle R. Bohnert, Ashok Kumar, Guangyan Xiong, Bradford G. Hill, Alex R. Straughn
Publikováno v:
Oncotarget
Chronic low-grade inflammation, adipocyte hypertrophy, and glucose intolerance are common features of obesity and a risk factor for cancer. Tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) is an adaptor protein that also possesses a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19845d2ad2facf89e933acb574c37b78
https://doi.org/10.18632/oncotarget.22575
https://doi.org/10.18632/oncotarget.22575
Autor:
Lubna Hindi, Guangyan Xiong, Jonghyun Shin, Yann S. Gallot, Sajedah M. Hindi, Adriana Simionescu-Bankston, Robert P. Friedland, Alex R. Straughn, Ashok Kumar
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications
Nature Communications
Myoblast fusion is an indispensable step for skeletal muscle development, postnatal growth, and regeneration. Myeloid differentiation primary response gene 88 (MyD88) is an adaptor protein that mediates Toll-like receptors and interleukin-1 receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5533e8ff4f46d91d47fa84c533bd4119
http://link.springer.com/article/10.1038/s41467-017-01866-w
http://link.springer.com/article/10.1038/s41467-017-01866-w
Autor:
Guangyan Xiong, Ashok Kumar, Aditya K. Sharma, Praneeth Goli, Anirban Roy, Yann S. Gallot, Kyle R. Bohnert
Publikováno v:
Molecular and Cellular Biology. 39
Skeletal muscle wasting causes both morbidity and mortality of cancer patients. Accumulating evidence suggests that the markers of endoplasmic reticulum (ER) stress and unfolded protein response (UPR) pathways are increased in skeletal muscle under m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6213debd80826f641d5a7ce8f36e23b9
https://doi.org/10.1128/mcb.00184-19
https://doi.org/10.1128/mcb.00184-19
Autor:
Yann S. Gallot, Kyle R. Bohnert, Alex R. Straughn, Guangyan Xiong, Sajedah M. Hindi, Ashok Kumar
Skeletal muscle mass is regulated by the coordinated activation of several anabolic and catabolic pathways. The endoplasmic reticulum (ER) is a major site of protein folding and a reservoir for calcium ions. Accretion of misfolded proteins or depleti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d953b94a9718c846678860046f1ed354
https://europepmc.org/articles/PMC6338633/
https://europepmc.org/articles/PMC6338633/
Publikováno v:
Plant Direct
Mutants affected in the Arabidopsis TBL29/ESK1 xylan O‐acetyltransferase display a strong reduction in total wall O‐acetylation accompanied by a dwarfed plant stature, collapsed xylem morphology, and enhanced freezing tolerance. A newly identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953898d88478a169cc4c7e853fd53374
http://europepmc.org/articles/PMC6508513
http://europepmc.org/articles/PMC6508513