Výsledky vyhledávání - "Guangxian Mao"

Akademický článek

Deciphering a cell death-associated signature for predicting prognosis and response to immunotherapy in lung squamous cell carcinoma

Autor: Guangxian Mao, Dongyong Yang, Bin Liu, Yu Zhang, Sijia Ma, Shang Dai, Guoqiang Wang, Wenxiang Tang, Huafei Lu, Shangli Cai, Jialiang Zhu, Huaping Yang

Publikováno v: Respiratory Research, Vol 24, Iss 1, Pp 1-14 (2023)

Abstract Background Lung squamous cell carcinoma (LUSC) is a subtype of non-small cell carcinoma, accounting for about 30% of all lung cancers. Yet, the evaluation of prognostic outcome and therapy response of patients with LUSC remains to be resolve

Externí odkaz: https://doaj.org/article/0a494fb671f24c739f7fd9a9c84de92d

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Akademický článek

Tumor Cell-Derived Exosomal miR-770 Inhibits M2 Macrophage Polarization via Targeting MAP3K1 to Inhibit the Invasion of Non-small Cell Lung Cancer Cells

Autor: Jixian Liu, Ruixing Luo, Junbin Wang, Xinyu Luan, Da Wu, Hua Chen, Qinghua Hou, Guangxian Mao, Xiaoqiang Li

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

BackgroundNon-small cell lung carcinoma (NSCLC) is a type lung cancer with high malignant behaviors. MicroRNAs (miRNAs) are known to be involved in progression of NSCLC. In order to explore potential targets for the treatment of NSCLC, bioinformatics

Externí odkaz: https://doaj.org/article/6fbce881ea0e4abab68bdd2a5903f021

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Exosomal lncRNA FOXD3-AS1 upregulates ELAVL1 expression and activates PI3K/Akt pathway to enhance lung cancer cell proliferation, invasion, and 5-fluorouracil resistance

Autor: Guangxian Mao, Zhimin Mu, Da Wu

Publikováno v: Acta Biochimica et Biophysica Sinica. 53:1484-1494

Long non-coding RNA (lncRNA) FOXD3-AS1 expression is upregulated in lung cancer; however, its effect and mechanism on 5-fluorouracil (5-FU) resistance remain unclear. In this study, we determined the effects of FOXD3-AS1-enriched exosomes derived fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e239e8fc510a3e5ba6c2c87df4bdb458
https://doi.org/10.1093/abbs/gmab129

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Targeted deep sequencing helps distinguish independent primary tumors from intrapulmonary metastasis for lung cancer diagnosis

Autor: Tanxiao Huang, Shifu Chen, Yingmei Li, Junbin Wang, Xinyu Luan, Weifeng Wang, Da Wu, Jing Zhang, Lili Tao, Ruixing Luo, Jixian Liu, Guangxian Mao, Mengmeng Xu, Xuxing Peng, Xiaoqiang Li

Publikováno v: Journal of Cancer Research and Clinical Oncology. 146:2359-2367

Multiple lung lesions found in a single patient at the time of diagnosis often pose a diagnostic dilemma: are these lesions independent primary tumors (IPT) or the result of intrapulmonary metastases (IPM)? While traditional pathological methods some

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f266c97ef9b1b4e3ef732b02afc9a08a
https://doi.org/10.1007/s00432-020-03227-5

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Exosome-derived miR-2682-5p suppresses cell viability and migration by HDAC1-silence-mediated upregulation of ADH1A in non-small cell lung cancer

Autor: Zhimin Mu, Guangxian Mao, Da Wu

Publikováno v: Humanexperimental toxicology. 40(12_suppl)

Introduction: Increasing evidence indicated that miR-2682-5p acted as a tumor suppressor in various cancers. The current study aimed to investigate the biological function of exosomal miR-2682-5p in non-small cell lung cancer (NSCLC). Methods: The ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4bd4a2e2949e938b4b22da29867aeb
https://pubmed.ncbi.nlm.nih.gov/34477002

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Tumor Cell-Derived Exosomal miR-770 Inhibits M2 Macrophage Polarization via Targeting MAP3K1 to Inhibit the Invasion of Non-small Cell Lung Cancer Cells

Autor: Junbin Wang, Jixian Liu, Ruixing Luo, Qinghua Hou, Da Wu, Guangxian Mao, Xinyu Luan, Hua Chen, Xiaoqiang Li

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38ccf2f4a3d90b9c97e6cdab0308f6a
https://www.frontiersin.org/articles/10.3389/fcell.2021.679658/full

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TW37 enhances the pro-apoptosis and anti-migration ability of gefitinib in Non-Small Cell Lung Cancer

Autor: Suyue Liu, Xiaofan Chen, Xiaoqiang Li, Guangxian Mao, Hao Wu, Sichao Wang, Hua Chen, Yiwang Ye, Jixian Liu

Publikováno v: Cellular and Molecular Biology. 64:6-10

B cell leukemia-2 (Bcl-2) plays important roles in the development of tumor and drug resistance. The growth of tumor cells can be inhibited by downregulating the abnormal expression of Bcl-2 protein. TW37, an effective inhibitor of Bcl-2 protein, has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6844f83a08fed2dc5dc9d2e32e88de
https://doi.org/10.14715/cmb/2018.64.4.2

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