Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Guangwen Ren"'
Autor:
Silvia Tiberti, Carlotta Catozzi, Ottavio Croci, Mattia Ballerini, Danilo Cagnina, Chiara Soriani, Caterina Scirgolea, Zheng Gong, Jiatai He, Angeli D. Macandog, Amir Nabinejad, Carina B. Nava Lauson, Arianna Quinte’, Giovanni Bertalot, Wanda L. Petz, Simona P. Ravenda, Valerio Licursi, Paola Paci, Marco Rasponi, Luca Rotta, Nicola Fazio, Guangwen Ren, Uberto Fumagalli-Romario, Martin H. Schaefer, Stefano Campaner, Enrico Lugli, Luigi Nezi, Teresa Manzo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
The tumor immune microenvironment is an important prognostic determinant in colorectal cancer (CRC). Here the authors show that tumor infiltrating neutrophils expressing high levels of CD15 interact with CD8+ T effector memory skewing them to produce
Externí odkaz:
https://doaj.org/article/d39113774e5e4720a4cf6ac291ef21d3
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/1f06a985084f47e183ac420c474e5c01
Autor:
Peishan Li, Ming Lu, Jiayuan Shi, Li Hua, Zheng Gong, Qing Li, Leonard D. Shultz, Guangwen Ren
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The role of neutrophils in the regulation of tumour growth and metastasis remains controversial. Here, the authors demonstrate that neutrophils, by exerting inhibitory effects on cytotoxic NK cells, show a net pro-metastatic effect in immune-competen
Externí odkaz:
https://doaj.org/article/8e4a51d014ec4176905300fb5f285823
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Intracellular cytokine staining (ICS) is a widely employed ex vivo method for quantitative determination of the activation status of immune cells, most often applied to T cells. ICS test samples are commonly prepared from animal or human tissues as u
Externí odkaz:
https://doaj.org/article/835b68d30124414790c20e12d1bf39f5
Autor:
Silvia Tiberti, Carlotta Catozzi, Ottavio Croci, Mattia Ballerini, Danilo Cagnina, Chiara Soriani, Caterina Scirgolea, Zheng Gong, Jiatai He, Angeli D. Macandog, Amir Nabinejad, Carina B. Nava Lauson, Arianna Quinte’, Giovanni Bertalot, Wanda L. Petz, Simona P. Ravenda, Valerio Licursi, Paola Paci, Marco Rasponi, Luca Rotta, Nicola Fazio, Guangwen Ren, Uberto Fumagalli-Romario, Martin H. Schaefer, Stefano Campaner, Enrico Lugli, Luigi Nezi, Teresa Manzo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/8a4381a2c8fa43b69113cd0ea77d9041
Autor:
Yufang Shi, Ying Wang, Arthur I. Roberts, Arnold B. Rabson, Xiaodong Chen, Liying Zhang, Guangwen Ren, Zengrong Yuan, Jimin Zhang, Weifang Ling
Mesenchymal stem cells (MSC) are present in most, if not all, tissues and are believed to contribute to tissue regeneration and the tissue immune microenvironment. Murine MSCs exert immunosuppressive effects through production of inducible nitric oxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::882fff75b60870829a138135c1b16e49
https://doi.org/10.1158/0008-5472.c.6505719
https://doi.org/10.1158/0008-5472.c.6505719
Autor:
Yufang Shi, Ying Wang, Arthur I. Roberts, Arnold B. Rabson, Xiaodong Chen, Liying Zhang, Guangwen Ren, Zengrong Yuan, Jimin Zhang, Weifang Ling
PDF file - 135KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250af084a0c0b52862d880afde372374
https://doi.org/10.1158/0008-5472.22400898.v1
https://doi.org/10.1158/0008-5472.22400898.v1
Autor:
Yufang Shi, Ying Wang, Arthur I. Roberts, Arnold B. Rabson, Xiaodong Chen, Liying Zhang, Guangwen Ren, Zengrong Yuan, Jimin Zhang, Weifang Ling
PDF file - 97KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589d7f4e5e6b8303cf3b775ba7fb76b8
https://doi.org/10.1158/0008-5472.22400904.v1
https://doi.org/10.1158/0008-5472.22400904.v1
Publikováno v:
Science Immunology. 8
Neutrophils, the most abundant innate immune cells, function as crucial regulators of the adaptive immune system in diverse pathological conditions, including metastatic cancer. However, it remains largely unknown whether their immunomodulatory funct
Autor:
Leonard D. Shultz, Li Hua, Bora Lim, Xiang Zhang, Qing Li, Zheng Gong, Sheng Li, Xiaowen Chen, Guangwen Ren, Jiayuan Shi, Mingyang Lu, Peishan Li
Publikováno v:
Nature immunology
Acquisition of a lipid-laden phenotype by immune cells has been defined in infectious diseases and atherosclerosis but remains largely uncharacterized in cancer. Here, in breast cancer models, we found that neutrophils are induced to accumulate neutr