Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Guangsong Su"'
Autor:
Tengfei Shi, Dianhao Guo, Yaoqiang Zheng, Wenbin Wang, Jinfang Bi, Anshun He, Sibo Fan, Guangsong Su, Xueyuan Zhao, Zhenhao Zhao, Yingjie Song, Shupeng Sun, Peng Li, Zhongfang Zhao, Jiandang Shi, Wange Lu, Lei Zhang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Glioma cell sensitivity to temozolomide (TMZ) is critical for effective treatment and correlates with patient survival, although mechanisms underlying this activity are unclear. Here, we reveal a new mechanism used by glioma cells to modulat
Externí odkaz:
https://doaj.org/article/3968c6b5c3f8445ea4776a806595d274
Autor:
Tong Zhao, Mingyang Cai, Man Liu, Guangsong Su, Daniel An, Byoungsan Moon, Guochang Lyu, Yibo Si, Lingyi Chen, Wange Lu
Publikováno v:
Stem Cell Reports, Vol 14, Iss 3, Pp 493-505 (2020)
Summary: Both 3D chromatin architecture and long non-coding RNAs (lncRNAs) play essential roles in pluripotency maintenance. However, whether lncRNAs are involved in organizing 3D chromatin structure remains largely unexplored. We identified 39 lncRN
Externí odkaz:
https://doaj.org/article/f6500fadbfe7404ea4d25f2c0c86c811
Autor:
Shaohui Chen, Bohan Chen, Guangsong Su, Jun Chen, Dianhao Guo, Qingqing Yin, Wenbin Wang, Zhongfang Zhao, Lei Zhang, Jiandang Shi, Wange Lu
Publikováno v:
Stem Cell Research, Vol 49, Iss , Pp 102097- (2020)
The developmental plasticity of embryonic stem cells (ESCs) is mainly controlled by well-characterized transcription factors, but additional factors, especially those related to metabolism that modulate this intrinsic program remain elusive. Here, us
Externí odkaz:
https://doaj.org/article/a68f5aadeff446f2903dceea796d47e1
Autor:
Wenjun Zhao, Lirong Wei, Dongming Tan, Guangsong Su, Yanwen Zheng, Chao He, Zhengwei J Mao, Timothy P Singleton, Bin Yin
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109198 (2014)
The mechanisms underlying acute myeloid leukemia (AML) treatment failure are not clear. Here, we established a mouse model of AML by syngeneic transplantation of BXH-2 derived myeloid leukemic cells and developed an efficacious Ara-C-based regimen fo
Externí odkaz:
https://doaj.org/article/087a1a846cec45ba98cb54c5075d607d
Autor:
Jinfang Bi, Wenbin Wang, Meng Zhang, Baoying Zhang, Man Liu, Guangsong Su, Fuquan Chen, Bohan Chen, Tengfei Shi, Yaoqiang Zheng, Xueyuan Zhao, Zhongfang Zhao, Jiandang Shi, Peng Li, Lei Zhang, Wange Lu
Publikováno v:
Nucleic Acids Research. 50:12235-12250
Neural differentiation of embryonic stem cells (ESCs) requires precisely orchestrated gene regulation, a process governed in part by changes in 3D chromatin structure. How these changes regulate gene expression in this context remains unclear. In thi
Autor:
Jun Chen, Bohan Chen, Jian Zheng, Guangsong Su, Jinfang Bi, Wange Lu, Lei Zhang, Wenbin Wang, Xueyuan Zhao, Man Liu, Jiandang Shi, Zhongfang Zhao, Dianhao Guo
Publikováno v:
Nucleic Acids Research
Signaling pathway-driven target gene transcription is critical for fate determination of embryonic stem cells (ESCs), but enhancer-dependent transcriptional regulation in these processes remains poorly understood. Here, we report enhancer architectur
Autor:
Dianhao Guo, Wange Lu, Lei Zhang, Jiandang Shi, Guangsong Su, Tengfei Shi, Heming Xu, Zhongfang Zhao, Jun Chen, Frank J. Attenello, Michelle A. Wedemeyer
Publikováno v:
Molecular Biology Reports. 47:2723-2733
The long noncoding RNA HOTAIRM1 reportedly plays important roles in acute myeloid leukemia, gastric cancer and colorectal cancer. Here, we analyzed potential function of HOTAIRM1 in glioma and asked whether it participates in long-range chromatin int
Autor:
Wange Lu, Mingyang Cai, Yibo Si, Guochang Lyu, Byoung-San Moon, Daniel An, Guangsong Su, Tong Zhao, Lingyi Chen, Man Liu
Publikováno v:
Stem Cell Reports, Vol 14, Iss 3, Pp 493-505 (2020)
Stem Cell Reports
Stem Cell Reports
Summary Both 3D chromatin architecture and long non-coding RNAs (lncRNAs) play essential roles in pluripotency maintenance. However, whether lncRNAs are involved in organizing 3D chromatin structure remains largely unexplored. We identified 39 lncRNA
Autor:
Guangsong Su, Wenbin Wang, Jun Chen, Man Liu, Jian Zheng, Dianhao Guo, Jinfang Bi, Zhongfang Zhao, Jiandang Shi, Lei Zhang, Wange Lu
Publikováno v:
Journal of Biological Chemistry. 298:102653
Autor:
Wenbin Wang, Anshun He, Bohan Chen, Jinfang Bi, Lei Zhang, Yiping Ma, Guangsong Su, Jiandang Shi, Zhongfang Zhao
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8337, p 8337 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences
Volume 22
Issue 15
Enhancers regulate multiple genes via higher-order chromatin structures, and they further affect cancer progression. Epigenetic changes in cancer cells activate several cancer-specific enhancers that are silenced in normal cells. These cancer-specifi