Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Guangshuo, Ou"'
Publikováno v:
PLoS Genetics, Vol 20, Iss 8, p e1011377 (2024)
Chemical mutagenesis-driven forward genetic screens are pivotal in unveiling gene functions, yet identifying causal mutations behind phenotypes remains laborious, hindering their high-throughput application. Here, we reveal a non-uniform mutation rat
Externí odkaz:
https://doaj.org/article/b0f33cd362eb4ca2af45060eaa4705cd
Autor:
Zhongyun Xie, Yongping Chai, Zhiwen Zhu, Zijie Shen, Zhengyang Guo, Zhiguang Zhao, Long Xiao, Zhuo Du, Guangshuo Ou, Wei Li
Publikováno v:
eLife, Vol 12 (2024)
Asymmetric cell divisions (ACDs) generate two daughter cells with identical genetic information but distinct cell fates through epigenetic mechanisms. However, the process of partitioning different epigenetic information into daughter cells remains u
Externí odkaz:
https://doaj.org/article/32946df5017140709e272acd271e582e
Autor:
Jie Ran, Guizhi Guo, Sai Zhang, Yufei Zhang, Liang Zhang, Dengwen Li, Shian Wu, Yusheng Cong, Xiaohong Wang, Songbo Xie, Huijie Zhao, Hongbin Liu, Guangshuo Ou, Xueliang Zhu, Jun Zhou, Min Liu
Publikováno v:
Advanced Science, Vol 11, Iss 25, Pp n/a-n/a (2024)
Abstract The photoreceptor cilium is vital for maintaining the structure and function of the retina. However, the molecular mechanisms underlying the photoreceptor cilium integrity and retinal homeostasis are largely unknown. Herein, it is shown that
Externí odkaz:
https://doaj.org/article/b77ae1bf12574273bab60b2a73cdc525
Autor:
Wei Li, Guangshuo Ou
Publikováno v:
Fundamental Research, Vol 4, Iss 3, Pp 695-696 (2024)
Externí odkaz:
https://doaj.org/article/179932cc1d834ad288ab2492ec80c306
Autor:
Kaiming Xu, Guangshuo Ou
Publikováno v:
Cell Regeneration, Vol 11, Iss 1, Pp 1-12 (2022)
Abstract Cilia are microtubule-based organelles projected from most eukaryotic cell surfaces performing cell motility and signaling. Several previously recognized non-ciliary proteins play crucial roles in cilium formation and function. Here, we prov
Externí odkaz:
https://doaj.org/article/b9f5cb560cbd489187292ee10d30af32
Autor:
Yongping Chai, Dong Tian, Zhiwen Zhu, Yuxiang Jiang, Shanjin Huang, Dou Wu, Guangshuo Ou, Wei Li
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract Asymmetric positioning of the mitotic spindle contributes to the generation of two daughter cells with distinct sizes and fates. Here, we investigated an asymmetric division in the Caenorhabditis elegans Q neuroblast lineage. In this divisio
Externí odkaz:
https://doaj.org/article/336ca131824941028a813bc4ff8b6635
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1010223 (2022)
Oncohistone mutations are crucial drivers for tumorigenesis, but how a living organism governs the loss-of-function oncohistone remains unclear. We generated a histone H2B triple knockout (3KO) strain in Caenorhabditis elegans, which decreased the em
Externí odkaz:
https://doaj.org/article/0ee34c591425487d8148461b5687d8ba
Autor:
Zhongyun Xie, Yongping Chai, Zhiwen Zhu, Zijie Shen, Zhengyang Guo, Zhiguang Zhao, Long Xiao, Zhuo Du, Guangshuo Ou, Wei Li
Publikováno v:
eLife; 7/12/2024, p1-28, 28p
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 6/18/2024, Vol. 121 Issue 25, p1-12, 28p
Autor:
Kaiming Xu, Guangshuo Ou
Publikováno v:
Cell Regeneration, Vol 11, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/b895521d307d4652bd4ac0727b4672c0