Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Guangsen Shi"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Patients with advanced idiopathic pulmonary fibrosis (IPF), a complex and incurable lung disease with an elusive pathology, are nearly exclusive candidates for lung transplantation. Improved identification of patient subtypes can enhance ear
Externí odkaz:
https://doaj.org/article/6d2f8a40e312491b87c30f2e05c0337a
Distinct Roles of HDAC3 in the Core Circadian Negative Feedback Loop Are Critical for Clock Function
Autor:
Guangsen Shi, Pancheng Xie, Zhipeng Qu, Zhihui Zhang, Zhen Dong, Yang An, Lijuan Xing, Zhiwei Liu, Yingying Dong, Guoqiang Xu, Ling Yang, Yi Liu, Ying Xu
Publikováno v:
Cell Reports, Vol 14, Iss 4, Pp 823-834 (2016)
In the core mammalian circadian negative feedback loop, the BMAL1-CLOCK complex activates the transcription of the genes Period (Per) and Cryptochrome (Cry). To close the negative feedback loop, the PER-CRY complex interacts with the BMAL1-CLOCK comp
Externí odkaz:
https://doaj.org/article/fce2c73e49b44b5f9a24f794737afc1d
Autor:
Zhiwei Liu, Moli Huang, Xi Wu, Guangsen Shi, Lijuan Xing, Zhen Dong, Zhipeng Qu, Jie Yan, Ling Yang, Satchidananda Panda, Ying Xu
Publikováno v:
Cell Reports, Vol 7, Iss 5, Pp 1509-1520 (2014)
Organization of circadian behavior, physiology, and metabolism is important for human health. An S662G mutation in hPER2 has been linked to familial advanced sleep-phase syndrome (FASPS). Although the paralogous phosphorylation site S714 in PER1 is c
Externí odkaz:
https://doaj.org/article/bbcb672c08d3414da4657c6b44f29748
Autor:
Zhipeng Qu, Hai Zhang, Moli Huang, Guangsen Shi, Zhiwei Liu, Pancheng Xie, Hui Li, Wei Wang, Guoqiang Xu, Yang Zhang, Ling Yang, Guocun Huang, Joseph S Takahashi, Weiping J Zhang, Ying Xu
Publikováno v:
eLife, Vol 5 (2016)
Many animals display morning and evening bimodal activities in the day/night cycle. However, little is known regarding the potential components involved in the regulation of bimodal behavioral rhythms in mammals. Here, we identified that the zinc fin
Externí odkaz:
https://doaj.org/article/4a26c1f8a0f84f73a3aaca6c743daccd
Autor:
Arisa Hirano, Guangsen Shi, Christopher R Jones, Anna Lipzen, Len A Pennacchio, Ying Xu, William C Hallows, Thomas McMahon, Maya Yamazaki, Louis J Ptáček, Ying-Hui Fu
Publikováno v:
eLife, Vol 5 (2016)
Familial Advanced Sleep Phase (FASP) is a heritable human sleep phenotype characterized by very early sleep and wake times. We identified a missense mutation in the human Cryptochrome 2 (CRY2) gene that co-segregates with FASP in one family. The muta
Externí odkaz:
https://doaj.org/article/136bb08d5052403ab88a6847a7402a92
Autor:
Lijuan Xing, Xianlin Zou, Chen Yin, Webb, John M., Guangsen Shi, Ptáček, Louis J., Ying-Hui Fu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 2/27/2024, Vol. 121 Issue 9, p1-10, 32p
Publikováno v:
2022 12th International Conference on Power and Energy Systems (ICPES).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56a8aa0816dc1efd618bf2424bd530a9
https://doi.org/10.1109/icpes56491.2022.10072538
https://doi.org/10.1109/icpes56491.2022.10072538
Autor:
Yulia Mostovoy, Chen Yin, Liza H. Ashbrook, Ying-Hui Fu, Guangsen Shi, Lijuan Xing, Pui-Yan Kwok, Zenghua Fan, Andrew D. Krystal, Louis J. Ptáček
Publikováno v:
Current biology : CB, vol 31, iss 1
Sufficient and efficient sleep is crucial for our health. Natural short sleepers can sleep significantly shorter than the average population without a desire for more sleep and without any obvious negative health consequences. In searching for geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944d4cff9e77e37ce8378d404c2a407b
https://pubmed.ncbi.nlm.nih.gov/33065013
https://pubmed.ncbi.nlm.nih.gov/33065013
Autor:
Lijuan Xing, Guangsen Shi, Dejing Pan, Pancheng Xie, Zhihui Zhang, Zhipeng Qu, Ying Xu, Jie Yan, Zhiwei Liu, Yang An
Publikováno v:
Journal of Biological Chemistry. 292:161-171
Understanding the mechanism underlying the physiological divergence of species is a long-standing issue in evolutionary biology. The circadian clock is a highly conserved system existing in almost all organisms that regulates a wide range of physiolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32dc00e6a69e9c193c0107ee1551161f
https://doi.org/10.1074/jbc.m116.751214
https://doi.org/10.1074/jbc.m116.751214
Autor:
Bilian Ke, Chengcheng Zhu, Xiaojun Hu, Xiaofei Jiang, Hong Liu, Ying Yuan, Guangsen Shi, Jiaojiao Deng
Publikováno v:
Current eye research. 45(5)
Purpose: This study aimed to evaluate the microbial contamination level and its influencing factors of rigid gas permeable (RGP) trial lenses and lens cases in China.Materials and Methods: A total ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6f0388a76602f0efc4e484c4fd3b5a
https://pubmed.ncbi.nlm.nih.gov/31697186
https://pubmed.ncbi.nlm.nih.gov/31697186