Výsledky vyhledávání - "Guangpei Chen"

Conference

The constituent elements of STEM education and their respective effect on talent cultivation performance in the unique context of China: A two-stage study.

Autor: Guangpei Chen¹, Yingying Qiao¹, Yiang Yang

Publikováno v: Proceedings of the ASEE Annual Conference & Exposition. 2023, p1-26. 26p.

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Conference

How Do Engineering Application-oriented Universities Positioning And Strategizing with External Actors? A Relational Dynamics Perspective.

Autor: Yingying Qiao¹, Guangpei Chen²

Publikováno v: Proceedings of the ASEE Annual Conference & Exposition. 2022, p1-18. 18p.

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Corilagin Restrains NLRP3 Inflammasome Activation and Pyroptosis through the ROS/TXNIP/NLRP3 Pathway to Prevent Inflammation

Autor: Tianyu Luo, Xiaoyi Zhou, Minyan Qin, Yuqing Lin, Jiefen Lin, Guangpei Chen, Aijun Liu, Dongyun Ouyang, Dongfeng Chen, Hao Pan

Publikováno v: Oxidative Medicine and Cellular Longevity.

Corilagin, a gallotannin, shows excellent antioxidant and anti-inflammatory effects. The NLRP3 inflammasome dysfunction has been implicated in a variety of inflammation diseases. However, it remains unclear how corilagin regulates the NLRP3 inflammas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5e7bd1421b6a4486d3dd460e3750cd

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Bmi1 Overexpression in Mesenchymal Stem Cells Exerts Antiaging and Antiosteoporosis Effects by Inactivating p16/p19 Signaling and Inhibiting Oxidative Stress

Autor: Guangpei Chen, Dengshun Miao, Wen Sun, Ying Zhang, Shuxiang Yu

Publikováno v: Stem Cells (Dayton, Ohio)

We previously demonstrated that Bmi1 deficiency leads to osteoporosis phenotype by inhibiting the proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells (MSCs), but it is unclear whether overexpression of Bmi1 in MSCs stim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c446a69973304889285c461d91f6311
http://europepmc.org/articles/PMC6851636

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DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide

Autor: Zhen Gu, David Goltzman, Haijian Sun, Ying Zhang, Guangpei Chen, Dengshun Miao, Andrew C. Karaplis

Publikováno v: International Journal of Biological Sciences

We previously demonstrated that parathyroid hormone-related peptide (PTHrP) 1-84 knockin (Pthrp KI) mice, which lacked a PTHrP nuclear localization sequence (NLS) and C-terminus, displayed early senescence, defective osteoblastic bone formation, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3737b6401356c3eb3fe2f66e2eec723a
http://europepmc.org/articles/PMC5968843

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Deficiency of the parathyroid hormone-related peptide nuclear localization and carboxyl terminal sequences leads to premature skin ageing partially mediated by the upregulation of p27

Autor: David Goltzman, Yongjie Zhang, Minyue Jiang, Andrew C. Karaplis, Dengshun Miao, Guangpei Chen, Na Lu, Shulei Jin

Publikováno v: Experimental dermatology. 24(11)

We previously reported that deficiency of the PTHrP nuclear localization sequence (NLS) and C-terminus in PTHrP knockin (PTHrP KI) mice resulted in premature ageing of skin. P27, a cyclin-dependent kinase inhibitor, was upregulated in PTHrP KI mice a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d0c837b2f467f53c4ed5e1eba43e69
https://pubmed.ncbi.nlm.nih.gov/26121068

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