Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Guanglei, Zhai"'
Autor:
Jin Xie, Mohamed Ouizougun-Oubari, Li Wang, Guanglei Zhai, Daitze Wu, Zhaohu Lin, Manfu Wang, Barbara Ludeke, Xiaodong Yan, Tobias Nilsson, Lu Gao, Xinyi Huang, Rachel Fearns, Shuai Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The transcription and replication processes of non-segmented, negative-strand RNA viruses (nsNSVs) are catalyzed by a multi-functional polymerase complex composed of the large protein (L) and a cofactor protein, such as phosphoprotein (P). P
Externí odkaz:
https://doaj.org/article/a605b25aaf124c108e54152f72438292
Autor:
Yusen Xiang, Guanglei Zhai, Yaozong Li, Mengge Wang, Xixiang Chen, Ruyu Wang, Hang Xie, Weidong Zhang, Guangbo Ge, Qian Zhang, Yechun Xu, Amedeo Caflisch, Jianrong Xu, Hongzhuan Chen, Lili Chen
Publikováno v:
International journal of biological macromolecules.
Targeting the interaction between the spike protein receptor binding domain (S-RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and angiotensin-converting enzyme 2 (ACE2) is a potential therapeutic strategy for treating coronaviru
Autor:
Ruyu, Wang, Guanglei, Zhai, Guanghao, Zhu, Mengge, Wang, Xiaoyi, Gong, Weidong, Zhang, Guangbo, Ge, Hongzhuan, Chen, Lili, Chen
Publikováno v:
Bioorganic Chemistry. 130:106264
Although the effective drugs or vaccines have been developed to prevent the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), their efficacy may be limited for the viral evolution and immune escape. Thus, it is urgently need
Autor:
Maarten Vercruysse, Yimin Hu, Yunhua Xu, Hua Lv, Waikwong Wu, Fabian Dey, Tianyi Jiang, Xuefei Tan, Wen Wang, Ying Ji, Zhiheng Xu, Zhang Zhiwei, Yi Mao, Kenneth Bradley, Guanglei Zhai, Liu Yongqiang, Xiangyu Yao, Qingcheng Ren, Hong C. Shen, S. Frank Yan, Xiao Ding, Weixing Zhang, Xiaomin Yu, Shi Houguang, Zhu Wei, Chengang Zhou, Mingwei Zhou, Zheng Zhou
Publikováno v:
Journal of Medicinal Chemistry. 63:9623-9649
The rise of multidrug resistant (MDR) Gram-negative (GN) pathogens and the decline of available antibiotics that can effectively treat these severe infections are a major threat to modern medicine. Developing novel antibiotics against MDR GN pathogen
Autor:
Rachel Fearns, Lu Gao, Guanglei Zhai, Daitze Wu, Shuai Chen, Li Wang, Xiaodong Yan, Manfu Wang, Jin Xie, Xinyi Huang, Zhaohu Lin
Human parainfluenza virus type 3 (hPIV3), a member of non-segmented, negative-strand RNA viruses (nsNSVs), is the second most common cause of severe respiratory disease in pediatrics. The transcription and replication processes of nsNSVs are catalyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::812ca11f36035de336dcc00f3a4c883d
https://doi.org/10.1101/2021.09.13.460081
https://doi.org/10.1101/2021.09.13.460081
Autor:
Yimin, Hu, Houguang, Shi, Mingwei, Zhou, Qingcheng, Ren, Wei, Zhu, Weixing, Zhang, Zhiwei, Zhang, Chengang, Zhou, Yongqiang, Liu, Xiao, Ding, Hong C, Shen, S Frank, Yan, Fabian, Dey, Waikwong, Wu, Guanglei, Zhai, Zheng, Zhou, Zhiheng, Xu, Ying, Ji, Hua, Lv, Tianyi, Jiang, Wen, Wang, Yunhua, Xu, Maarten, Vercruysse, Xiangyu, Yao, Yi, Mao, Xiaomin, Yu, Kenneth, Bradley, Xuefei, Tan
Publikováno v:
Journal of medicinal chemistry. 63(17)
The rise of multidrug resistant (MDR) Gram-negative (GN) pathogens and the decline of available antibiotics that can effectively treat these severe infections are a major threat to modern medicine. Developing novel antibiotics against MDR GN pathogen